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  1. Efficient convergent boundary integral methods for slender bodies

    Publication
    The interaction of fibers in a viscous (Stokes) fluid plays a crucial role in industrial and biological processes, such as sedimentation, rheology, transport, cell division, and locomotion. Numerical …

  2. Multiscale simulations of molecular recognition by phase separated MUT-16: A scaffolding protein of Mutator foci

    Publication
    … the mutation of seven Arg residues in MUT-16 to Lys and Ala weakens MUT-8 binding in vitro.

  3. Design of Coiled-Coil Protein Nanostructures for Therapeutics and Drug Delivery

    Publication
    Coiled-coil protein motifs have become widely employed in the design of biomaterials. Some of these designs have been studied for use in drug delivery due to the …

  4. Improvement of variant reclassification in genetic neurodevelopmental conditions.

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  5. Pathogenic gating pore current conducted by autism-related mutations in the NaV1.2 brain sodium channel.

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  6. Deep Learning Sequence Models for Transcriptional Regulation

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    Deciphering the regulatory code of gene expression and interpreting the transcriptional effects of genome variation are critical challenges in human genetics. Modern experimental technologies have resulted in an …

  7. SimBIG: Cosmological Constraints using Simulation-Based Inference of Galaxy Clustering with Marked Power Spectra

    Publication
    We present the first \(\Lambda\)CDM cosmological analysis performed on a galaxy survey using marked power spectra. The marked power spectrum is the two-point function of a …

  8. Impact of a genetic diagnosis for a child's autism on parental perceptions.

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  9. A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus.

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  10. Identification of moderate effect size genes in autism spectrum disorder through a novel gene pairing approach.

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  11. Effects of parental age and polymer composition on short tandem repeat de novo mutation rates.

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  12. Clinical correlates of diagnostic certainty in children and youths with autistic disorder.

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  13. Evidence-based recruitment strategies for clinical research: Study personnel's and research participants' perceptions about successful methods of outreach for a U.S. Autism-Research Cohort.

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  14. Tidal Disruption Encores

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    Nuclear star clusters (NSCs), made up of a dense concentrations of stars and the compact objects they leave behind, are ubiquitous in the central regions of galaxies, surrounding …

  15. Simulating X-Ray Reverberation in the Ultraviolet-emitting Regions of Active Galactic Nuclei Accretion Disks with Three-dimensional Multifrequency Radiation Magnetohydrodynamic Simulations

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    Active galactic nuclei (AGN) light curves observed with different wave bands show that the variability in longer wavelength bands lags the variability in shorter wavelength bands. Measuring these …

  16. The Next Generation Deep Extragalactic Exploratory Public (NGDEEP) Survey

    Publication
    We present the Next Generation Deep Extragalactic Exploratory Public (NGDEEP) Survey, a deep slitless spectroscopic and imaging Cycle 1 JWST treasury survey designed to constrain feedback mechanisms in …

  17. First Sagittarius A* Event Horizon Telescope Results. VIII. Physical Interpretation of the Polarized Ring

    Publication
    In a companion paper, we present the first spatially resolved polarized image of Sagittarius A* on event horizon scales, captured using the Event Horizon Telescope, a global very …

  18. First Sagittarius A* Event Horizon Telescope Results. VII. Polarization of the Ring

    Publication
    The Event Horizon Telescope observed the horizon-scale synchrotron emission region around the Galactic center supermassive black hole, Sagittarius A* (Sgr A*), in 2017. These observations revealed a …

  19. The JWST Resolved Stellar Populations Early Release Science Program. V. DOLPHOT Stellar Photometry for NIRCam and NIRISS

    Publication
    We present NIRCam and NIRISS modules for DOLPHOT, a widely used crowded-field stellar photometry package. We describe details of the modules including pixel masking, astrometric alignment, star …

  20. The Sun Remains Relatively Refractory Depleted: Elemental Abundances for 17,412 Gaia RVS Solar Analogs and 50 Planet Hosts

    Publication
    The element abundances of stars, particularly the refractory elements (e.g., Fe, Si, and Mg), play an important role in connecting stars to their planets. Most Sun-like …

  21. [C II] Emission in a Self-regulated Interstellar Medium

    Publication
    The [CII] 157.74 \(\mu\)m fine structure transition is one of the brightest and most well-studied emission lines in the far-infrared (FIR), produced in the …

  22. Leaving No Branches Behind: Predicting Baryonic Properties of Galaxies from Merger Trees

    Publication
    Galaxies play a key role in our endeavor to understand how structure formation proceeds in the Universe. For any precision study of cosmology or galaxy formation, there is …

  23. GOALS-JWST: Gas Dynamics and Excitation in NGC 7469 Revealed by NIRSpec

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    We present new JWST-NIRSpec IFS data for the luminous infrared galaxy NGC7469: a nearby (70.6Mpc) active galaxy with a Sy 1.5 nucleus that drives a …

  24. Latent Stochastic Differential Equations for Modeling Quasar Variability and Inferring Black Hole Properties

    Publication
    Quasars are bright and unobscured active galactic nuclei (AGN) thought to be powered by the accretion of matter around supermassive black holes at the centers of galaxies. The …

  25. A Perspective on the Milky Way Bulge Bar as Seen from the Neutron-capture Elements Cerium and Neodymium with APOGEE

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    This study probes the chemical abundances of the neutron-capture elements cerium and neodymium in the inner Milky Way from an analysis of a sample of $\sim$2000 …

  26. Was There a 3.5 keV Line?

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    The 3.5 keV line is a purported emission line observed in galaxies, galaxy clusters, and the Milky Way whose origin is inconsistent with known atomic transitions and …

  27. Closing the Gap between Observed Low-mass Galaxy H I Kinematics and Cold Dark Matter Predictions

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    Testing the standard cosmological model (ΛCDM) at small scales is challenging. Galaxies that inhabit low-mass dark matter halos provide an ideal test bed for dark matter models …

  28. Modelling Time-dependent Convective Penetration in 1D Stellar Evolution

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    One-dimensional stellar evolution calculations produce uncertain predictions for quantities like the age, core mass, core compactness, and nucleosynthetic yields; a key source of uncertainty is the modeling …

  29. COSMOS-Web: Intrinsically Luminous z \(\gtrsim\) 10 Galaxy Candidates Test Early Stellar Mass Assembly

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    We report the discovery of 15 exceptionally luminous \(10\lesssim z\lesssim14\) candidate galaxies discovered in the first 0.28 deg\(^2\) of JWST/NIRCam imaging from the …

  30. A Joint Fermi-GBM and Swift-BAT Analysis of Gravitational-wave Candidates from the Third Gravitational-wave Observing Run

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    We present Fermi Gamma-ray Burst Monitor (Fermi-GBM) and Swift Burst Alert Telescope (Swift-BAT) searches for gamma-ray/X-ray counterparts to gravitational-wave (GW) candidate …

  31. A Joint Fermi-GBM and Swift-BAT Analysis of Gravitational-wave Candidates from the Third Gravitational-wave Observing Run

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    We present Fermi Gamma-ray Burst Monitor (Fermi-GBM) and Swift Burst Alert Telescope (Swift-BAT) searches for gamma-ray/X-ray counterparts to gravitational-wave (GW) candidate …

  32. In This Day and Age: An Empirical Gyrochronology Relation for Partially and Fully Convective Single Field Stars

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    Gyrochronology, the field of age dating stars using mainly their rotation periods and masses, is ideal for inferring the ages of individual main-sequence stars. However, due to …

  33. Parameter-Free Tour of the Binary Black Hole Population

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    The continued operation of the Advanced LIGO and Advanced Virgo gravitational-wave detectors is enabling the first detailed measurements of the mass, spin, and redshift distributions of the …

  34. Source confusion from neutron star binaries in ground-based gravitational wave detectors is minimal

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    Upgrades beyond the current second generation of ground-based gravitational wave detectors will allow them to observe tens of thousands neutron star and black hole binaries. Given the …

  35. Field-level simulation-based inference of galaxy clustering with convolutional neural networks

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    We present the first simulation-based inference (SBI) of cosmological parameters from field-level analysis of galaxy clustering. Standard galaxy clustering analyses rely on analyzing summary statistics, such …

  36. Galaxy clustering analysis with SimBIG and the wavelet scattering transform

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    The non-Gaussisan spatial distribution of galaxies traces the large-scale structure of the Universe and therefore constitutes a prime observable to constrain cosmological parameters. We conduct Bayesian …

  37. Cosmological constraints from the nonlinear galaxy bispectrum

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    We present the first cosmological constraints from analyzing higher-order galaxy clustering on non-linear scales. We use \({\rm S{\scriptsize IM}BIG}\), a forward modeling framework for …

  38. Cosmological baryon spread and impact on matter clustering in CAMELS

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    We quantify the cosmological spread of baryons relative to their initial neighboring dark matter distribution using thousands of state-of-the-art simulations from the Cosmology and Astrophysics …

  39. A Dusty Locale: evolution of galactic dust populations from Milky Way to dwarf-mass galaxies

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    Observations indicate dust populations vary between galaxies and within them, suggesting a complex life cycle and evolutionary history. Here we investigate the evolution of galactic dust populations across …

  40. Differentiable stochastic halo occupation distribution

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    In this work, we demonstrate how differentiable stochastic sampling techniques developed in the context of deep reinforcement learning can be used to perform efficient parameter inference over stochastic …

  41. Making the unmodulated Pyramid wavefront sensor smart. Closed-loop demonstration of neural network wavefront reconstruction with MagAO-X

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    Almost all current and future high-contrast imaging instruments will use a Pyramid wavefront sensor (PWFS) as a primary or secondary wavefront sensor. The main issue with the …

  42. Zooming in on the circumgalactic medium with GIBLE. The topology and draping of magnetic fields around cold clouds

    Publication
    We use a cosmological zoom-in simulation of a Milky Way-like galaxy to study and quantify the topology of magnetic field lines around cold gas clouds in …

  43. The size-luminosity relation of local active galactic nuclei from interferometric observations of the broad-line region

    Publication
    By using the GRAVITY instrument with the near-infrared (NIR) Very Large Telescope Interferometer (VLTI), the structure of the broad (emission-)line region (BLR) in active galactic nuclei …

  44. Self-reported everyday sources of happiness and unhappiness in autistic adults.

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  45. Perspectives on employer-initiated terminations among young adults on the autism spectrum.

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  46. The Hund-metal path to strong electronic correlations

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  47. Galaxy clustering analysis with SimBIG and the wavelet scattering transform

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    The non-Gaussian spatial distribution of galaxies traces the large-scale structure of the Universe and therefore constitutes a prime observable to constrain cosmological parameters. We conduct Bayesian …

  48. Increased anticholinergic medication use in middle-aged and older autistic adults and its associations with self-reported memory difficulties and cognitive decline.

    Publication