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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Quantum Cafe: Giorgio Sangiovanni

    Colloquium
    Title: Correlated Dirac and Weyl Semimetals Abstract: We study the resistivity of three-dimensional semimetals with linear dispersion in the presence of on-site electron-electron interaction. The …
  2. CCQ Current and Past Quantum Cafe Schedules

    Colloquium
  3. Seminar and Problem Sessions on Mathematics of Deep Learning

    Seminar
  4. CCM Seminar Schedule

    Seminar
  5. Neuromatch 4.0

    Related
    The scope of NMC4 includes computational neuroscience and machine learning work that has a biological link. The event will include a combination of virtual and in-person conference …
  6. CCQ Current and Past Workshop Schedules

    Workshop
  7. 2021 Fall CCA Colloquium Schedule

    Colloquium
  8. CCB Colloquium: Stephan Grill

    Colloquium
    Topic: Cluster of Excellence Physics of Life Abstract: One of the most remarkable examples of self-organized structure formation is the development of a complex organism from a …
  9. Lectures on Diagrammatic Monte Carlo: Corentin Bertrand

    Lecture
    All lectures in this series will be held 10-11:15am US EDT and are open to all interested scientists. For further information please contact Dr. Igor Tupitsyn …
  10. MAIN 2021: Montreal AI & Neuroscience

    Related
    Two days of talks, keynote lectures and discussion panels at the crossroads of biological and artificial intelligence. Watch out also for the 2-day educational session on Nov …
  11. Mathematics of Deep Learning Seminar: Andrea Montanari

    Seminar
    Title: Tractability, generalization and overparametrization in linear and nonlinear models Abstract: Empirical risk minimization (ERM) is the dominant paradigm in statistical learning. Optimizing the empirical risk of neural …
  12. Scientific Computing Seminar & Concepts talk: Barry Smith

    Meeting
    Title: Preconditioners for linear systems
  13. CCA Colloquium: Jo Dunkley

    Colloquium
    Please email [email protected] for Zoom information if you would like to participate. Title: The Millimeter Sky from the Atacama Cosmology Telescope Abstract: I will show maps …
  14. Simons Collaboration on Homological Mirror Symmetry Annual Meeting 2021

    Conference
    … mirror symmetry, formulated by Kontsevich in 1994, naturally produces hosts of homological invariants. Sometimes, it can be made manifest, and then its striking mathematical power comes to …
  15. (Homological) Knot Invariants From Mirror Symmetry

    Lecture
    Quantum invariants of knots (also known as Chern-Simons knot invariants) have many applications in mathematics and physics. For example, Khovanov showed in 1999 that the simplest such …
  16. Hormone Circuits Interest Group

    Meeting
    The group will focus on studying *hormone circuits*, which impact so much of human biology, disease (e.g. diabetes, depression) and behavior. No background is needed. The overall …
  17. CCM Colloquium: Stéphane Mallat

    Colloquium
    Title: Hamiltonian Estimations by Inverse Renormalisation Group and Convolution Nets Abstract: Estimating high-dimensional probability distributions and physical Hamiltonians from data is an old outstanding problem. It is …
  18. CCB Colloquium: Richard Mann

    Colloquium
    Title: How flies make and use their appendages Abstract: My plan is to present an overview of the current efforts in my lab, providing necessary background when needed …
  19. Lectures on Diagrammatic Monte Carlo: Fluctuation diagnostics on the scattering origins of the strange metal states (Wei Wu)

    Lecture
    All lectures in this series will be held 10-11:15am US EDT and are open to all interested scientists. For further information please contact Dr. Igor Tupitsyn …
  20. SMBp Seminar: Paul Kim

    Seminar
    Speaker: Paul Kim, Software Engineer, Simons Machine Learning Center Title: Learning to automate Cryo-EM data collection with Ptolemy Abstract: Over the past decade, cryogenic electron microscopy (cryo …
  21. Society for Neuroscience’s 50th Annual Meeting

    Related
    SfN's 50th annual meeting is the premier venue for neuroscientists to present emerging science, learn from experts, forge collaborations with peers, explore new tools and technologies, and …
  22. Bayes Reading Group

    Meeting
    Discussion Lead: Lester Mackey, Microsoft Research/Stanford University Topic: Kernel and Stein thinning for MCMC Link: TBD
  23. Simons Collaboration on the Nonperturbative Bootstrap Annual Meeting 2021

    Conference
    … holes provide a window into quantum gravity and how scientists use the ‘bootstrap’ technique to study them. This line of research leads from black hole thermodynamics to …
  24. Black Holes and Quantum Gravity

    Lecture
    Black holes have mysterious properties that indicate that they are composed of an enormous number of microscopic parts. This has led to the idea that in quantum gravity …
  25. Quantum Cafe: Giulia Galli

    Colloquium
    Title: Embedding theories for quantum simulations on hybrid classical-quantum architectures Abstract: We discuss a recently developed quantum embedding theory [1] scalable to large systems, and its application …
  26. CCB Colloquium: Elizabeth Gavin

    Colloquium
    Presenter: Dr. Elizabeth R. Gavin, Ph.D., DamonB. Pfeiffer Professor of MolecularBiology Associated Faculty of the Princeton Neuroscience Institute Princeton University Topic: Looking to the future: assembly and …
  27. Mathematics of Deep Learning Seminar: Mikhail Belkin

    Seminar
    Title: The Polyak-Lojasiewicz condition as a framework for over-parameterized optimization and its application to deep learning Abstract: The success of deep learning is due, to a …
  28. CCA Colloquium: TBD

    Colloquium
    Please email [email protected] for Zoom information if you would like to participate.
  29. Bayes Reading Group

    Meeting
    Discussion Lead: Lee Devilin & Simon Maskell, Liverpool University Topic: Lee Devlin, Paul Horridge, Peter L. Green, Simon Maskell. 2021. The no-U-turn sampler as a proposal distribution …
  30. Biophysics Development Seminar

    Seminar
    Presenter: M. Cristina Marchetti, Ph.D., Professor, Physics University of California, Santa Barbara Topic: Interfacial properties of active fluids Abstract: There are many situations where active fluids coexist …
  31. DeepMath 2021

    Related
    Recent advances in deep neural networks (DNNs), combined with open, easily-accessible implementations, have made DNNs a powerful, versatile method used widely in both machine learning and neuroscience …
  32. Measuring and Hedging Geopolitical Risk

    Lecture
    Some events can impact the volatilities of most assets, asset classes, sectors and countries, causing severe damage to investment portfolios. The magnitude of such shocks is defined as …
  33. CCA Colloquium: Saul Teukolsky

    Colloquium
    Title: The Coming Revolution in Computational Astrophysics Abstract: Large-scale computer simulations are increasingly crucial in explaining astrophysical phenomena. Just one recent example is the stunning agreement of …
  34. Mathematics of Deep Learning Seminar: Jiequn Han

    Seminar
    Title: Perturbational Complexity by Distribution Mismatch: A Systematic Analysis of Reinforcement Learning in Reproducing Kernel Hilbert Space Abstract: Most existing theoretical analysis of reinforcement learning (RL) is limited …
  35. CCB Colloquium: Ray Goldstein

    Colloquium
    Presenter: Professor Raymond E. Goldstein FRS Schlumberger Professor of Complex Physical Systems Department of Applied Mathematics and Theoretical Physics Centre for Mathematical SciencesUniversity of Cambridge Topic: Cytoplasmic Streaming …
  36. Lectures on Diagrammatic Monte Carlo: Discovering new phases of matter with unsupervised and interpretable support vector machines (Lode Pollet)

    Lecture
    All lectures in this series will be held 10-11:15am US EDT and are open to all interested scientists. For further information please contact Dr. Igor Tupitsyn …
  37. 2021 Fall CCB Colloquia Schedule

    Colloquium
  38. CCQ Current and Past Quantum Cafe Schedules

    Colloquium
  39. Seminar and Problem Sessions on Mathematics of Deep Learning

    Seminar
  40. CCM Seminar Schedule

    Seminar
  41. CCQ Current and Past Workshop Schedules

    Workshop
  42. 2021 Fall CCA Colloquium Schedule

    Colloquium
  43. Bayes Reading Group Meeting

    Meeting
    Discussion Lead: Charles Margossian, Columbia University Topic: Nested Rhat: Assessing Convergence for Markov chains Monte Carlo when using many short chains Please email Cindy Rampersad at crampersad@flatironinstitute …
  44. Charlie Marcus and Michael Freedman Lectures

    Lecture
    You’re invited to join two talks on Friday, October 29th, 10 am – 12 pm. Both will be hybrid events, held in the 2nd floor auditorium (IDA) as …
  45. High Dimensional Expanders in Theoretical Computer Science

    Lecture
    Expander graphs have been useful in computer science with versatile applications, including coding theory, networking, computational complexity and geometry. High-dimensional expanders are a generalization that has been …
  46. CCA Colloquium: Bruce Draine

    Colloquium
    Title: A New Model for Interstellar Dust: “Astrodust” + PAHs Abstract: Observations strongly suggest that interstellar dust in the Milky Way consists predominantly of a single composite material, which …
  47. Quantum Cafe: Nadya Mason

    Colloquium
    Title: Surface State Magnetoresistance in 3D Topological Insulators Abstract: Topological insulators (TIs) have a variety of unique transport properties, including strong spin-orbit coupling and symmetry-protected spin …
  48. 2021 MPS Conference on High-Dimensional Expanders

    Conference
    … will not be granted without this documentation. On-site registration will not be permitted. Walk-in entry will be denied. October 27, 2021 Henry Yuen | Noncommutative Property …
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