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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. 2021 Simons Collaboration on Cracking the Glass Problem Annual Meeting

    Conference
    … in Structural Glasses: P. Urbani Excitations in Low-Temperature Glasses: E. Lerner Quantum Disordered Systems: A. Rosso Mathematical Methods for Diluted Mean-Field Models: A. Coja-Oglan …
  2. The Quest for the Ideal Glass

    Lecture
    Most of the materials around us are structurally disordered, from window glass to emulsions to biological tissues. Scientists have long considered disordered materials as imperfect or defective versions …
  3. NeuRise Seminar Series: Inter-areal communication

    Related
    A neuroscience seminar series for postdocs and graduate students. Talks will take place every other week on Wednesdays (March 10, 24 and April 7, 21, Wednesdays at 5pm …
  4. Special Seminar: Yao-Yuan Mao

    Seminar
    For more information go here. March 9, 2021 Yao-Yuan Mao: Fundamental Physics of Dark Matter from Dwarf Galaxy Surveys
  5. Brown Bag Seminar

    Meeting
    Speaker: Maria Avdeeva, Ph.D, Associate Research Scientist, DevDy Topic: A data fusion approach to developmental patterning
  6. Quantum Cafe Webinar: Lucile Savary

    Colloquium
    Title: Thermal transport in quantum magnets Abstract: I will present some general results for all components of the thermal conductivity tensor in magnets, especially useful in regimes where …
  7. Mathematics of Deep Learning Seminar: Eric Darve

    Seminar
    Title: Physics-informed machine learning: open mathematical questions Abstract: The requirements and constraints to numerically solve physics-informed machine learning problems (PhysML) are notably different from classical machine …
  8. Biophysics & Development Seminar: Gregory Voth, University of Chicago

    Lecture
    Presenter: Gregory A. Voth, Ph.D., FRSC Department of Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL Topic: Overcoming the Multiscale …
  9. Biophysical Modeling Group Meeting

    Meeting
    Presenter: Leroy Jia, Ph.D., Topic: The odd flows of an active chiral annulus/Ideas about Langmuir films
  10. Systems Biology Group Meeting

    Meeting
    Presenter: Aaron Watters, Ph.D., Senior Software Engineer, Flatiron Institute Title: Landscapes of Binary Classification Ranking Abstract: This talk informally explores and compares methods for evaluating binary classification …
  11. BRAIN Connectivity Workshop Series - Workshop 3

    Related
    This series of workshops, co-hosted by The National Institutes of Health (NIH) BRAIN Initiative and the Department of Energy (DOE) Office of Science, brings together researchers with …
  12. Special Seminar: Michael Hahn

    Seminar
    Title: Alfven Wave Damping and Heating in the Solar Corona Abstract: Understanding the heating of the solar corona has been considered one of the major problems in astrophysics …
  13. Ancient DNA and the New Science of the Human Past

    Lecture
    Scientists sequenced the first ancient human genomes in 2010, and since then, more than 5000 additional ancient genomes have been published. That work makes it possible to ask …
  14. Virtual SCGB West Coast Postdoc/Student Meeting

    SCGB
    The Simons Collaboration on the Global Brain hosts a West Coast group meeting to bring together postdocs and PhD students interested in neural coding and dynamics. This month …
  15. Mathematics of Deep Learning Seminar: Risi Kondor

    Seminar
    Title: The representation theory of equivariant neural networks and graph neural nets Abstract: Incorporating symmetries is an important theme in several branches of deep learning. However, there are …
  16. 2021 CCA Colloquium Schedule

    Colloquium
    Spring 2021 Date Name Title January 29, 2021 Mike Blanton TBD February 5, 2021 Nick Battaglia TBD February 12, 2021 Andrei Beloborodov TBD February 26, 2021 Lam Hui …
  17. Biophysics & Development Seminar: Jane Kondev, Ph.D., Brandeis University

    Seminar
    Presenter: Jane Kondev, Ph.D., Brandeis University Topic: How Cells Measure Length
  18. CCQ Current and Past Quantum Cafe Schedules

    Colloquium
  19. Mathematics of Deep Learning Seminar Schedule

    Seminar
  20. Biophysical Modeling Group Meeting

    Meeting
    Presenter: Reza Farhadifar, Ph.D. Topic: From one to many: can we compute the embryo?
  21. Systems Biology Group Meeting

    Meeting
    Presenter: Andreas Tjarnberg, Postdoctoral Associate, New York University Title: Translating gene regulatory network inference into a white-box deep learning framework Abstract: Gene regulatory network (GRN) inference is …
  22. CCQ Current and Past Workshop Schedules

    Workshop
  23. Biophysics and Development Seminar Series

    Seminar
  24. What You Need to Know About the COVID-19 Vaccines

    In Conversation
    In this virtual conversation, New York Times science and global health reporter Apoorva Mandavilli will chat with Peter Hotez, dean of Baylor University’s National School of Tropical …
  25. Drosophila Journal Club

    Meeting
  26. Computational Bayesian Statistics Journal Club

    Meeting
    Discussion Lead: Philip Greengard [Columbia U] Paper: Greengard, Gelman, and Vehtari. 2020. A Fast Linear Regression via SVD and Marginalization. https://arxiv.org/abs/2011.04829 Please email …
  27. CCA Fall 2020 Pre-Doctoral Symposium

    Symposia
    February 26, 2021 2020 Pre-Doctoral Symposium
  28. Genomics Group Meeting

    Meeting
  29. Special Seminar: Collin Capano

    Seminar
    For more information go here. February 25, 2021 Probing Fundamental Physics With Gravitational Waves
  30. Clinical Trials and Cyclic AMP in Fragile X Syndrome: A Life Journey

    Lecture
    Fragile X syndrome (FXS) was thought to be a model neurodevelopmental disorder for the translation of mechanism-targeted treatments from basic neuroscience and animal models to patients. Thus …
  31. Computational and Systems Neuroscience (Cosyne) 2021

    Related
    The annual Cosyne meeting provides an inclusive forum for the exchange of experimental and theoretical/computational approaches to problems in systems neuroscience. Cosyne topics include (but are not …
  32. Special Seminar: Alice Pisani

    Seminar
    For more information go here. February 23, 2021 Alice Pisani: Precision Cosmology with Cosmic Voids
  33. Brown Bag Seminar

    Lecture
    Speaker: Wen Yan, Ph.D. Research Scientist, Biophysical Modeling Topic: From pairwise crosslinker kinetics to collective bundling in active assemblies.
  34. Quantum Cafe Webinar: Lei Wang

    Colloquium
    Title: Neural Canonical Transformations Abstract: Canonical transformations play fundamental roles in simplifying and solving physical systems. However, their design and implementation can be challenging in the many-particle …
  35. Mathematics of Deep Learning Seminar: Jianfeng Lu

    Seminar
    Title: Towards numerical analysis for solving high dimensional PDEs based on neural networks Abstract: Numerical solution to high dimensional PDEs has been one of the central challenges in …
  36. Boston-Area Postdoc/Student Meeting

    SCGB
    The Simons Collaboration on the Global Brain hosts a Boston-area group meeting to bring together postdocs and PhD students interested in neural coding and dynamics to discuss …
  37. Systems Biology Group Meeting

    Meeting
    Presenter: Claudia Skok Gibbs, Research Analyst, Systems Biology Group, Center for Computational Biology, Flatiron Institute Title: Learning cell-type-specific single-cell gene regulatory networks in the developing …
  38. Biophysics & Development Seminar: Enrico Coen

    Lecture
    Presenter: Enrico Coen, Ph.D., Group Leader / Fellow of the Royal Society Topic: From Patterning to Morphogenesis
  39. Streams 21: Constraints on Dark Matter

    Conference
    February 22, 2021 Streams 21 – Day 1: Milky Way Streams and Substructure February 23, 2021 Streams 21 – Day 2: Large-Scale Constraints on Dark Matter February 24, 2021 …
  40. Drosophila Journal Club

    Meeting
  41. Computational Bayesian Statistics Journal Club

    Meeting
    Discussion Lead: Will Grathwohl [U Toronto] Paper: Grathwohl, Swersky, Hashemi, Duvenaud, Maddison. 2021. Oops I Took A Gradient: Scalable Sampling for Discrete Distributions. https://arxiv.org/abs/2102 …
  42. Simons Collaboration on Algorithms and Geometry Monthly Meeting, February 2021

    Conference
    1:00 – 3:00 PM Agenda 1:00 -1:55 PM Shachar Lovett The Sunflower Conjecture: Part 1 (Background, related results, general approach, etc) 1:55 – 2:00 …
  43. Simons Collaboration on Localization of Waves Annual Meeting 2021 (Online)

    Conference
    … Jerison: The Geometry of Level Sets of Eigenfunctions February 19, 2021 Claude Weisbuch: Landscape Localization Theory: A new tool to describe alloy-based semiconductor devices
  44. Genomics Group Meeting

    Meeting
  45. Special Seminar: Nathan Leigh

    Seminar
    Title: Constructing a Factory for Predicting Merger Rates of Black Hole Pairs Abstract: In this talk, I will briefly review the general three-body problem and its present …
  46. The Third Pillar of Science

    Lecture
    In the late 20th century, science underwent a revolution as computational science emerged as the third mode of scientific inquiry alongside experiment and theory. Computer simulation of physical …
  47. BRAIN Connectivity Workshop Series - Workshop 2

    Related
    This series of workshops, co-hosted by The National Institutes of Health (NIH) BRAIN Initiative and the Department of Energy (DOE) Office of Science, brings together researchers with …
  48. DevDy Group Meeting

    Meeting
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