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  1. FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells.

    Publication

  2. Normative framework for deriving neural networks with multi-compartmental neurons and non-Hebbian plasticity

    Publication
    An established normative approach for understanding the algorithmic basis of neural computation is to derive online algorithms from principled computational objectives and evaluate their compatibility with anatomical and …

  3. Distinct roles of putative excitatory and inhibitory neurons in the macaque inferior temporal cortex in core object recognition behavior.

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  4. A fast time domain solver for the equilibrium Dyson equation

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    We consider the numerical solution of the real time equilibrium Dyson equation, which is used in calculations of the dynamical properties of quantum many-body systems. We show …

  5. Spin-Flip Unitary Coupled Cluster Method: Toward Accurate Description of Strong Electron Correlation on Quantum Computers

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  6. Simple extension of the plane-wave final state in photoemission: Bringing understanding to the photon-energy dependence of two-dimensional materials

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  7. Time-dependent ghost Gutzwiller nonequilibrium dynamics

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  8. Enhancement of charge density wave correlations in a Holstein model with an anharmonic phonon potential

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  9. Low-Scaling Algorithm for the Random Phase Approximation Using Tensor Hypercontraction with k-point Sampling

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  10. Chiral model of twisted bilayer graphene realized in a monolayer

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  11. Pressure-enhanced fractional Chern insulators along a magic line in moiré transition metal dichalcogenides

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  12. Topological superconductivity in doped magnetic moirè semiconductors

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  13. Conformational heterogeneity and probability distributions from single-particle cryo-electron microscopy

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    Single-particle cryo-electron microscopy (cryo-EM) is a technique that takes projection images of biomolecules frozen at cryogenic temperatures. A major advantage of this technique is its …

  14. The contributions of rare inherited and polygenic risk to ASD in multiplex families.

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  15. Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders.

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  16. Conformational heterogeneity and probability distributions from single-particle cryo-electron microscopy

    Publication
    Single-particle cryo-electron microscopy (cryo-EM) is a technique that takes projection images of biomolecules frozen at cryogenic temperatures. A major advantage of this technique is its …

  17. The Autism Symptom Dimensions Questionnaire: Development and psychometric evaluation of a new, open-source measure of autism symptomatology.

    Publication

  18. On Single Index Models beyond Gaussian Data

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    Sparse high-dimensional functions have arisen as a rich framework to study the behavior of gradient-descent methods using shallow neural networks, showcasing their ability to perform feature …

  19. Generative modeling via tensor train sketching

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    In this paper, we introduce a sketching algorithm for constructing a tensor train representation of a probability density from its samples. Our method deviates from the standard recursive …

  20. Large-scale whole genome sequence analysis of 22,000 subjects provides no evidence of FMR1 premutation allele involvement in autism spectrum disorder.

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  21. VBASS enables integration of single cell gene expression data in Bayesian association analysis of rare variants.

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  22. Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data

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    Resolving chromatin-remodeling-linked gene expression changes at cell-type resolution is important for understanding disease states. Here we describe MAGICAL (Multiome Accessibility Gene Integration Calling and Looping …

  23. Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice.

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  24. A Model-Based Method for Minimizing CVaR and Beyond

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    We develop a variant of the stochastic prox-linear method for minimizing the Conditional Value-at-Risk (CVaR) objective. CVaR is a risk measure focused on minimizing worst …

  25. SGD with Large Step Sizes Learns Sparse Features

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    We showcase important features of the dynamics of the Stochastic Gradient Descent (SGD) in the training of neural networks. We present empirical observations that commonly used large step …

  26. BridgeStan: Efficient in-memory access to the methods of a Stan model

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    Stan provides a probabilistic programming language in which users can code Bayesian models (Carpenter et al., 2017; Stan Development Team, 2022). A Stan program is transpiled to to …

  27. Maintaining symmetry during body axis elongation

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    Bilateral symmetry defines much of the animal kingdom and is crucial for numerous functions of bilaterian organisms. Genetic approaches have discovered highly conserved patterning networks that establish bilateral …

  28. Rhesus macaque social functioning is paternally, but not maternally, inherited by sons: Potential implications for autism.

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  29. Unlocking the Potential of Similarity Matching: Scalability, Supervision and Pre-training

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    While effective, the backpropagation (BP) algorithm exhibits limitations in terms of biological plausibility, computational cost, and suitability for online learning. As a result, there has been a growing …

  30. Kernelized Diffusion Maps

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    Spectral clustering and diffusion maps are celebrated dimensionality reduction algorithms built on eigen-elements related to the diffusive structure of the data. The core of these procedures is …

  31. Reprogramming method does not impact the neuronal differentiation potential of 16p11.2 deletion patient iPSCs.

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  32. A note about convected time derivatives for flows of complex fluids

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    We present a direct derivation of the typical time derivatives used in a continuum description of complex fluid flows{,} harnessing the principles of the kinematics of line elements …

  33. ANK2 loss-of-function variants are associated with epilepsy, and lead to impaired axon initial segment plasticity and hyperactive network activity in hiPSC-derived neuronal networks.

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  34. A mixed methods study of autistic adults' mental health therapy experiences.

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  35. Changes in social behavior with MAPK2 and KCTD13/CUL3 pathways alterations in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders.

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  36. Many-body delocalization from embedded thermal inclusion

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  37. Nonequilibrium correlation dynamics in the one-dimensional Fermi-Hubbard model: A testbed for the two-particle reduced density matrix theory

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  38. Spin-valley magnetism on the triangular moiré lattice with SU(4) breaking interactions

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  39. A qualitative exploration of autistic mothers' experiences I: Pregnancy experiences.

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  40. Are autistic people disadvantaged by the criminal justice system? A case comparison.

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  41. Phenotypically driven subgroups of ASD display distinct metabolomic profiles.

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  42. Relationship between childhood obesity and autism spectrum disorder varies by child's age and parents' weight status in a sample of sibling dyads.

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  43. Autistic people's perinatal experiences II: A survey of childbirth and postnatal experiences.

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  44. Validity of the SNAP-IV for ADHD assessment in South African children with neurodevelopmental disorders.

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  45. Autism spectrum disorders and brain volume link through a set of mTOR-related genes.

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  46. Multi-omic analysis along the gut-brain axis points to a functional architecture of autism.

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  47. Phenotypic effects of genetic variants associated with autism.

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  48. Developmental molecular controls over arealization of descending cortical motor pathways.

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