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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Computational Bayesian Statistics Journal Club

    Meeting
    Discussion Leader: Michael Eickenberg and Marylou Gabrié, CCM; Flatiron Institute. Reading: Kingma, D.P. and Welling, M., 2013. Auto-encoding variational Bayes. https://arxiv.org/pdf/1312.6114 …
  2. Neuroscience Group Meeting

    Meeting
    Speaker: Tiberiu Tesileanu Topic: Online Bayesian time series segmentation: towards neural implementations. Join from PC, Mac, Linux, iOS or Android: https://simonsfoundation.zoom.us/j/98487246580?pwd=ZDFmSFQrSWlndm1sWW1jRWtxZWE4Zz09
  3. Genomic Group Meeting

    Meeting
  4. Developmental Dynamics Group Meeting

    Meeting
  5. Brown Bag Seminar

    Lecture
    Topic: A tale of two systems: Exploring the regulatory landscape of the IBD gut immune system Join from PC, Mac, Linux, iOS or Android: https://simonsfoundation.zoom.us …
  6. Neuroscience Group Meeting

    Meeting
    Speaker: Yanis Bahroun Topic: NeurIPS submission: A neurally plausible minor subspace analyzer balances feedforward excitation and inhibition. Most neural circuits in the brain include inhibitory neurons in various …
  7. 2020 Spring CCB Colloquia Schedule

    Colloquium
  8. Virtual BRAIN Investigators Meeting

    Related
    The BRAIN Initiative Investigators Meeting will convene BRAIN Initiative awardees, staff, and leadership from the contributing federal agencies (NIH, NSF, DARPA, IARPA, and FDA), plus representatives and investigators …
  9. CCQ Current and Past Quantum Cafe Schedules

    Lecture
  10. CCQ Current and Past Workshop Schedules

    Workshop
  11. 2020 Spring CCA Friday Colloquium: Charlie Conroy

    Colloquium
  12. From parent advocate to nonprofit chief science officer, to biotherapeutic company cofounder — A personal journey through drug development for Angelman syndrome

    Lecture
    Allyson Berent discussed the journey that led her to becoming chief science officer of the largest research funding foundation for Angelman syndrome in the world (Foundation for Angelman …
  13. Neuroscience Group Meeting

    Meeting
    Zoom Info: Join from PC, Mac, Linux, iOS or Android: https://simonsfoundation.zoom.us/j/732630308 Or Telephone: Dial(for higher quality, dial a number based on your …
  14. Gravitational Waves Group Meeting

    Meeting
    Please contact ([email protected]) at least 24hrs in advance, if you would like to be added to the participant list to attend this meeting.
  15. Virtual Quantum Cafe: Gabriel Aeppli

    Lecture
    Quantum Café is CCQ’s ongoing seminar series: open to all bona fide members of the greater NYC scientific community and held every second week, Quantum Café presents …
  16. CCM Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  17. Systems Biology Group Meeting

    Meeting
    Speaker: Andreas Tjarnberg
  18. Neuromatch 2.0

    Related
    An unconference in Computational Neuroscience. Based on the successful mind-matching session at the Cognitive Computational Neuroscience (CCN) conference, we decided to create a free web-based unconference …
  19. Neuroscience Group Meeting

    Meeting
    Presenter: David Lipshutz, Associate Research Scientist Topic: NeurIPS submission: “Nonnegative Independent Component Analysis” Zoom Info: Join from PC, Mac, Linux, iOS or Android: https://simonsfoundation.zoom.us/j …
  20. Computational Bayesian Statistics Journal Club

    Meeting
    Discussion Leader: Jamie Morton, CCB Flatiron Institute Main reading: https://arxiv.org/pdf/1903.11695.pdf Optional readings: https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-018-0584 …
  21. CCM Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  22. Virtual SCGB NY-Area Postdoc Meeting

    SCGB
    The Simons Collaboration on the Global Brain hosts a postdoc-focused NYC-area group meeting every other month to bring together postdocs interested in neural coding and dynamics …
  23. Virtual Dopamine Conference

    Related
    ViDA 2020 will focus on the cutting-edge discoveries in dopamine research from a broad range of approaches, from molecular to systems and computational neuroscience. Join us for …
  24. Brown Bag Seminar

    Lecture
  25. Systems Biology Group Meetings

    Meeting
    Speaker: Claudia Skok Gibbs
  26. Climate Change: What’s New?

    In Conversation
    Human emissions of greenhouse gases now overwhelm the influence of natural drivers in altering Earth's climate. How will our energy choices and resulting emissions affect temperature and …
  27. Neuroscience Group Meeting

    Meeting
    Presenters: Charlie Windolf & David Lipshutz Topic: Slow feature analysis Zoom Link Join from PC, Mac, Linux, iOS or Android: https://simonsfoundation.zoom.us/j/732630308
  28. Computational Bayesian Statistics Journal Club

    Meeting
    Discussion Leader: Simon Manskell, Liverpool University Topic: Sequential Monte Carlo [1] P L Green, R E Moore, R J Jackson, J Li and S Maskell. Increasing the efficiency …
  29. Canceled: Simons Collaboration on Algorithms and Geometry 2020 Annual Meeting

    Conference
    The Algorithms and Geometry Annual Meeting is canceled. Please contact Meghan Fazzi with any questions. Contacts General Meeting Assistance Meghan Fazzi Senior Executive Assistant, Simons Foundation mfazzi@simonsfoundation …
  30. Neuroscience Seminar

    Meeting
    Speaker: Jeffrey C. McGee, PhD Title: Adaptive hippocampal representations generated by a directed synaptic plasticity The seminar will be followed by an informal discussion for anyone interested. Zoom …
  31. CCM Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  32. Canceled: Simons Society of Fellows Weekly Dinner - May 13, 2020

    Meeting
    .m-block-description .m-meta__muted, .o-blocks__left .m-block-meta:last-child{display:none}
  33. Neurodata Without Borders Virtual User Days

    Related
    The Neurodata Without Borders: Neurophysiology project (NWB) is an effort to standardize the description and storage of neurophysiology data and metadata.The purpose of the hackathon is to …
  34. Systems Biology Group Meeting

    Meeting
    Speaker: Douglas Renfrew
  35. 2020 Spring CCA Friday Colloquium: Janna Levin

    Colloquium
  36. Computational Bayesian Statistics Journal Club

    Meeting
    … with Koopman are implicit in it), you can check out this paper: Transition path theory analysis of c-Src kinase activation https://www.pnas.org/content/113 …
  37. Neuroscience Group Meeting

    Meeting
    Speaker: Siavash Golkar Topic: NeurIPS submission on biologically plausible Reduced Rank Regression Zoom Info: Join from PC, Mac, Linux, iOS or Android: https://simonsfoundation.zoom.us/j/732630308 …
  38. CCM Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  39. Canceled: Simons Society of Fellows Weekly Dinner - May 6, 2020

    Meeting
    .m-block-description .m-meta__muted, .o-blocks__left .m-block-meta:last-child{display:none}
  40. Progress in understanding the genetic basis of mental health

    Lecture
    Benjamin Neale discussed progress in mapping genetic risk factors for autism, schizophrenia and bipolar disorder.
  41. Progress in Understanding the Genetic Basis of Mental Health

    Lecture
    The past decade has seen rapid progress in mapping genetic risk factors for autism, schizophrenia and bipolar disorder. In this talk, Benjamin Neale will review this progress, delving …
  42. Brown Bag Seminar

    Lecture
    Topic: Enabling reproducibility through large-scale continuous scientific benchmarks for applications in Rosetta Computational methods should be inherently reproducible. However, changes in the code, input options, and different …
  43. Systems Biology Group Meeting

    Meeting
    Speaker: Anders Rasmussen
  44. 2020 Spring CCA Friday Colloquium

    Colloquium
    Spring 2020 Date Name Title 1/31/20 Gwen Eadie Astrostatistics in the Era of Large Surveys: from the Milky Way to individual stars 2/7/20 Saurabh …
  45. 2020 Spring CCA Friday Colloquium: Jen van Saders

    Colloquium
  46. 2020 Spring CCB Colloquia Schedule

    Colloquium
  47. Computational Bayesian Statistics Journal Club

    Meeting
    Lead: Mariano Gabitto, Flatiron Institute Topic: The discussion will focus on: Antonietta Mira, Reza Solgi, and Daniele Imparato. 2013. Zero variance Markov chain Monte Carlo for Bayesian estimators …
  48. CCQ Current and Past Quantum Cafe Schedules

    Lecture
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