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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Choice selective inhibition drives stability and competition in decision circuits

    Publication
  2. An empirical model of the Gaia DR3 selection function

    Publication
    Interpreting and modelling astronomical catalogues requires an understanding of the catalogues' completeness or selection function: objects of what properties had a chance to end up in the catalogue …
  3. X chromosome factor Kdm6a enhances cognition independent of its demethylase function in the aging XY male brain

    Publication
  4. Behavioral origin of sound-evoked activity in mouse visual cortex

    Publication
  5. A General Framework for Inferring Bayesian Ideal Observer Models from Psychophysical Data

    Publication
  6. Parametric control of flexible timing through low-dimensional neural manifolds

    Publication
  7. The geometry of cortical representations of touch in rodents

    Publication
  8. Formalising social representation to explain psychiatric symptoms

    Publication
  9. A mesothelium divides the subarachnoid space into functional compartments

    Publication
  10. One dimensional approximations of neuronal dynamics reveal computational strategy

    Publication
  11. The centrality of population-level factors to network computation is demonstrated by a versatile approach for training spiking networks

    Publication
  12. An approximate line attractor in the hypothalamus encodes an aggressive state

    Publication
  13. Neural decoding of emotional prosody in voice-sensitive auditory cortex predicts social communication abilities in children.

    Publication
  14. Differential Expression Analysis of Nothobranchius furzeri Transposable Elements from RNA-seq Data

    Publication
  15. Measuring subjective quality of life in autistic adults with the PROMIS global-10: Psychometric study and development of an autism-specific scoring method.

    Publication
  16. Social support and links to quality of life among middle-aged and older autistic adults.

    Publication
  17. Use of a Best Practice Alert (BPA) to increase diversity within a U.S.-based autism research cohort.

    Publication
  18. Phenotypic shift in copy number variants: Evidence in 16p11.2 duplication syndrome.

    Publication
  19. Measuring subjective quality of life in autistic adults with the PROMIS global-10: Psychometric study and development of an autism-specific scoring method.

    Publication
  20. Social support and links to quality of life among middle-aged and older autistic adults.

    Publication
  21. Utilization of a Best Practice Alert (BPA) at Point-of-Care for Recruitment into a U.S.-Based Autism Research Study.

    Publication
  22. Sensitivity analysis of simulation-based inference for galaxy clustering

    Publication
    Simulation-based inference (SBI) is a promising approach to leverage high-fidelity cosmological simulations and extract information from the non-Gaussian, non-linear scales that cannot be modelled …
  23. Respective Roles of Electron-Phonon and Electron-Electron Interactions in the Transport and Quasiparticle Properties of SrVO

    Publication
  24. Respective Roles of Electron-Phonon and Electron-Electron Interactions in the Transport and Quasiparticle Properties of SrVO

    Publication
  25. Fully ab-initio all-electron calculation of dark matter--electron scattering in crystals with evaluation of systematic uncertainties

    Publication
  26. Absence of quantization in the circular photogalvanic effect in disordered chiral Weyl semimetals

    Publication
  27. Chern mosaic and ideal flat bands in equal-twist trilayer graphene

    Publication
  28. Edge zeros and boundary spinons in topological Mott insulators

    Publication
  29. Nature of even and odd magic angles in helical twisted trilayer graphene

    Publication
  30. Geometric Stiffness in Interlayer Exciton Condensates

    Publication
  31. Unveiling order from chaos by approximate 2-localization of random matrices

    Publication
  32. Variational adiabatic transport of tensor networks

    Publication
  33. Imaging Self-aligned Moiré Crystals and Quasicrystals in Magic-angle Bilayer Graphene on hBN Heterostructures

    Publication
  34. Low-Scaling algorithms for GW and constrained random phase approximation using symmetry-adapted interpolative separable density fitting

    Publication
  35. Adiabatic dynamics of coupled spins and phonons in magnetic insulators

    Publication
  36. Semiempirical \(\textit{ab initio}\) modeling of bound states of deep defects in semiconductor quantum technologies

    Publication
    The performance of semiconductor devices can be enhanced by understanding and characterizing the bound states of deep defects. However, simulating these states using conventional
  37. Finite-Temperature Quantum Matter with Rydberg or Molecule Synthetic Dimensions

    Publication
  38. Automated detection of laser cooling schemes for ultracold molecules

    Publication
  39. The chiral limits of moiré semiconductors: origin of flat bands and topology in twisted transition metal dichalcogenides homobilayers

    Publication
  40. Keldysh field theory of dynamical exciton condensation transitions in nonequilibrium electron-hole bilayers

    Publication
  41. Analytic continuation of multipoint correlation functions

    Publication
  42. Gauging tensor networks with belief propagation

    Publication
  43. Low-energy perspective on two-orbital Hund metals and the case of LaNiO2

    Publication
  44. Downfolding from Ab Initio to Interacting Model Hamiltonians: Comprehensive Analysis and Benchmarking

    Publication
  45. Geometric squeezing of rotating quantum gases into the lowest Landau level

    Publication
  46. Metallic quantum criticality enabled by flat bands in a kagome lattice

    Publication
  47. Symmetry constraints and spectral crossing in a Mott insulator with Green's function zeros

    Publication
  48. Signature of Correlated Insulator in Electric Field Controlled Superlattice

    Publication
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