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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Biophysical Modeling Group Meeting

    Meeting
  2. Systems Biology Group Meeting

    Meeting
    Topic: Modeling Structure in Single-cell Chromatin Data. In recent years, single-cell technologies have revolutionized biology, providing exciting opportunities to map cellular populations through development. Among these …
  3. Big Apple Colloquium

    Colloquium
    Tentative Schedule Open House: 10:00am-12:00pm Colloquium: 3:00pm
  4. Simons Collaboration on Algorithms and Geometry Monthly Meeting, November 2019

    Conference
    … stochastic calculus and the analysis of jump processes). Our method resolves a ’96 conjecture of Talagrand, deriving a bound which strengthens both Talagrand’s isoperimetric inequality and …
  5. Neuroscience Group Meeting

    Meeting
    Speaker: Nikolai Chapochnikov Topic: Presentation of figures for the paper: “Mechanistic model for ZCA-type whitening in the olfactory circuit of the drosophila larva
  6. ACT Mapping Workshop

    Workshop
    Workshop focused on ACT mapping and TOD analysis including s17, s18, HWP, daytime data.
  7. From genotype to phenotype in autism: The role of adaptive physiology in flies and mice

    Lecture
    On November 20, 2019, Graeme Davis presented his research investigating the mechanisms that lie at the interface between neuronal homeostatic plasticity and ASD genetics.
  8. From Genotype to Phenotype in Autism: The Role of Adaptive Physiology in Flies and Mice

    Lecture
    The identification of rare de novo mutations that confer high risk for autism spectrum disorders (ASD) has generated tremendous new molecular insight and progress. Yet, in cases where …
  9. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  10. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  11. SCGB NY-Area Postdoc Meeting

    SCGB
    The Simons Collaboration on the Global Brain hosts a postdoc-focused NYC-area group meeting every other month to bring together postdocs interested in neural coding and dynamics …
  12. SCGB West Coast Postdoc Meeting

    SCGB
    The Simons Collaboration on the Global Brain invites hosts a quarterly west coast postdoc meeting series to bring together postdocs interested in neural coding and dynamics to discuss …
  13. CCB Colloquium: Thierry Emonet

    Colloquium
    Topic: Conflicts and synergies between individuality and collective behavior Cells live in communities where they interact with each other and their environment. By coordinating individuals, such interactions often …
  14. CCB Seminar: Yuhai Tu

    Seminar
    Topic: Nonequilibrium Statistical Physics of Biochemical Oscillators: Phase Accuracy, Entrainability, and Synchronization Abstract: A central question in biology is how living systems manage to process information and perform …
  15. Max Planck-New York Center for Nonequilibrium Quantum Phenomena: Signing Ceremony, Symposium and Workshop

    Event
  16. CCA Colloquium: Rosalba Perna

    Colloquium
    November 15, 2019 Rosalba Perna: Mergers of Compact-Objects In the Gravitational Wave Era
  17. Neuroscience Group Meeting

    Meeting
    Canonical Correlation Analysis model of the cortical microcircuit Yanis Bahroun and David Lipshutz will be leading a discussion on extensions of Canonical Correlation Analysis to more than two …
  18. Simons Collaboration on Homological Mirror Symmetry Annual Meeting 2019

    Conference
    … assumptions. He will then report on ongoing work regarding applications to symplectic manifolds that are presented as the total space of a Lagrangian fibration or the union …
  19. From Equivariant Blow-Ups to Modular Symbols

    Lecture
    Part of the beauty of mathematics is the interplay between its different branches. In this lecture, Maxim Kontsevich will talk about a recent discovery of an unexpected relation …
  20. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  21. CCB Colloquium: Michael Hiller

    Colloquium
    Presenter: Michael Hiller, Max Planck Institute, Dresden Topic: Linking phenotypic differences between species to differences in genes and cis-regulatory elements Identifying the DNA changes that underlie phenotypic …
  22. The Math Puzzle That Spawned 100 Philosophy Papers

    In Conversation
    At first glance, the Sleeping Beauty problem appears to be a simple question about probability. But since being proposed 19 years ago by philosopher Adam Elga, the problem …
  23. CCA Colloquium: Jess Werk

    Colloquium
    November 8, 2019 Jess Werk: The Circumgalactic Medium
  24. Machine Learning working group meeting

    Meeting
    Leslie Greengard from CCM will present more on the topic of the adjoint method, and optimization for electromagnetic beam steering (a more detailed version of his talk at …
  25. Neuroscience Group Meeting

    Lecture
    Topic: Clustering time series in the brain: connections to information theory, canonical correlations, and cepstra Sensory information reaches the brain as a stream with non-trivial correlations across …
  26. Simons Collaboration on the Nonperturbative Bootstrap Annual Meeting 2019

    Conference
    … setup based on QFT in AdS where the same constraints follow from an entirely different set of axioms, and comment on the relation between correlators and amplitudes …
  27. Reductionism vs Bootstrap: Are Things Big Always Made of Things Elementary?

    Lecture
    slava Scientists love to reduce physical systems to a few elementary blocks, which they use like Lego building blocks to build more complicated ‘composite’ objects. Geoffrey Chew in …
  28. Quantum Cafe: Roger Melko

    Lecture
    Quantum Café is CCQ’s ongoing seminar series: open to all bona fide members of the greater NYC scientific community and held every second week, Quantum Café presents …
  29. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  30. CCB Colloquium: Joakim Lunderberg

    Colloquium
    Title: Molecular maps in tissue and disease by data-driven analysis of spatially resolved transcriptomes in situ. Abstract: RNA-sequencing offers the possibility to analyze the expression of …
  31. Systems Biology Group Meeting

    Meeting
    Presenter: Michelle Badri, Ph.D. Candidate New York Univesity Title: Applying natural language processing methods to building models of the microbiome Integrating datasets from multiple “omic” datasets is …
  32. CCA Colloquia Schedule

    Event
    … 10, 2019 John Wise he First Stars, Black Holes, and Galaxies in the Universe May 17, 2019 Mark Krumholz Star formation, turbulence, transport, and feedback: towards a …
  33. CCQ Current and Past Quantum Cafe Schedules

    Lecture
    Quantum Café is CCQ’s ongoing seminar series: open to all bona fide members of the greater NYC scientific community and held every second week, Quantum Café presents …
  34. CCB Colloquia Schedule

    Event
  35. CCQ Current and Past Workshop Schedules

    Lecture
  36. Neuroimmune interactions shaping social behavior in mouse models for neurodevelopmental disorders

    Lecture
    On October 30, 2019, Gloria Choi discussed her work using mouse models of maternal immune activation to study the role of maternal infection in neurodevelopmental disorders, such as …
  37. Neuroimmune Interactions Shaping Social Behavior in Mouse Models for Neurodevelopmental Disorders

    Lecture
    Viral infection during pregnancy correlates with increased frequency of neurodevelopmental disorders in offspring. This phenomenon has been modeled in mice prenatally subjected to maternal immune activation (MIA). In …
  38. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  39. 2019 Flatiron Wide Algorithms and Mathematics

    Conference
    FWAM (“Flatiron-wide Autumn Meeting”, previously “Flatiron-wide Algorithms and Mathematics”) is a two-day internal conference with the goal of introducing and reviewing scientific and computational tools …
  40. Brown Bag Seminar

    Lecture
    Speaker: Jamie Morton Topic: Learning representations of microbe–metabolite interactions
  41. SCGB Boston-area Postdoc Meeting Series

    Event
    The Simons Collaboration on the Global Brain hosts a postdoc-focused Boston-area group meeting every other month to bring together postdocs interested in neural coding and dynamics …
  42. Biophysical Modeling Group Meeting

    Meeting
    Title: Self-organisation of bidirectional microtubule networks is robust: a mathematical framework and validation in Drosophila. You and I are but a collection of trillions of cells. Why …
  43. Systems Biology Group Meeting

    Meeting
    Title: Methods for analysis of spatial transcriptomics data with application to amyotrophic lateral sclerosis Spatial genomics technologies enable new approaches to study how cells interact and function in …
  44. Junior Scientist Workshop on Theoretical Neuroscience

    Related
    This workshop is intended as a "by the students, for the students" meeting. Participants will include only students and postdocs doing theoretical neuroscience research. Over the course of …
  45. CCA Colloquium: Maryam Modjaz

    Colloquium
    Title: Stellar Forensics with the most powerful explosions in the Universe Abstract: Supernovae (SNe) and Long-duration Gamma-ray Bursts (GRBs) are exploding stars and constitute the most …
  46. Neuroscience Group Meeting

    Meeting
    Speaker: Nicholas Chua Topic: Feedback on figures for the lamina paper
  47. High Dimensional Expanders

    Lecture
    Expander graphs, particularly Ramanujan graphs, have been a major focus of research over the last five decades. This research has yielded fruitful interactions between mathematics and computer science …
  48. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
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