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  1. Genome-wide rare variant score associates with morphological subtypes of autism spectrum disorder.

    Publication

  2. The implications of categorical and category-free mixed selectivity on representational geometries

    Publication

  3. Clinical characteristics of youth with autism or developmental disability during inpatient psychiatric admission.

    Publication

  4. Visual and motor signatures of locomotion dynamically shape a population code for feature detection in Drosophila

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  5. Catching actin proteins in action

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    Two groups have visualized actin — the protein polymer that gives cells their shape — at high resolution. The structures provide in-depth views of the polymer as it adopts …

  6. A unified theory for the computational and mechanistic origins of grid cells

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    The discovery of entorhinal grid cells has generated considerable interest in how and why hexagonal firing fields might emerge in a generic manner from neural circuits, and what …

  7. Measuring the dimensionality of behavior

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  8. Neural representational geometry underlies few-shot concept learning

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  9. Coding of latent variables in sensory, parietal, and frontal cortices during closed-loop virtual navigation

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  10. Observation of room temperature excitons in an atomically thin topological insulator

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  11. Circulating Klotho Is Higher in Cerebrospinal Fluid than Serum and Elevated Among KLOTHO Heterozygotes in a Cohort with Risk for Alzheimer's Disease

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  12. In vivo proximity ligation reveals endogenous candidate interactors of neurexin's intracellular domain.

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  13. Production of MHCII-expressing classical monocytes increases during aging in mice and humans

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  14. Could dexmedetomidine be repurposed as a glymphatic enhancer?

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  15. Learning shapes cortical dynamics to enhance integration of relevant sensory input

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    Adaptive sensory behavior is thought to depend on processing in recurrent cortical circuits, but how dynamics in these circuits shapes the integration and transmission of sensory information is …

  16. Rhesus monkey sociality is stable across time and linked to variation in the initiation but not receipt of prosocial behavior.

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  17. Associations between executive functioning, challenging behavior, and quality of life in children and adolescents with and without neurodevelopmental conditions.

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  18. Multibody molecular docking on a quantum annealer

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    Molecular docking, which aims to find the most stable interacting configuration of a set of molecules, is of critical importance to drug discovery. Although a considerable number of …

  19. Dynamics, scaling behavior, and control of nuclear wrinkling

    Publication
    The cell nucleus is enveloped by a complex membrane, whose wrinkling has been implicated in disease and cellular aging. The biophysical dynamics and spectral evolution of nuclear wrinkling …

  20. Hyperexcitable and immature-like neuronal activity in the auditory cortex of adult rats lacking the language-linked CNTNAP2 gene.

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  21. Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder?

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  22. Protocol for iterative optimization of modified peptides bound to protein targets

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    Peptides are commonly used as therapeutic agents. However, they suffer from easy degradation and instability. Replacing natural by non-natural amino acids can avoid these problems, and potentially …

  23. Modeling and inference methods for switching regime-dependent dynamical systems with multiscale neural observations

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  24. Behavioural and dopaminergic signatures of resilience

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  25. Visuomotor learning promotes visually evoked activity in the medial prefrontal cortex

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  26. Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations.

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  27. Circumbinary discs for stellar population models

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    We develop a rapid algorithm for the evolution of stable, circular, circumbinary discs suitable for parameter estimation and population synthesis modelling. Our model includes disc mass and angular …

  28. A Mirage or an Oasis? Water Vapor in the Atmosphere of the Warm Neptune TOI-674 b

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    We report observations of the recently discovered warm Neptune TOI-674 b (5.25 rearth{}, 23.6 mearth{}) with the Hubble Space Telescope's Wide Field Camera 3 …

  29. Forced and spontaneous symmetry breaking in cell polarization

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    How does breaking the symmetry of an equation alter the symmetry of its solutions? Here, we systematically examine how reducing underlying symmetries from spherical to axisymmetric influences the …

  30. Optimal noise level for coding with tightly balanced networks of spiking neurons in the presence of transmission delays

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  31. Cerebellar atypicalities in autism?

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  32. Stepped-care cognitive behavioral therapy in children on the autism spectrum with co-occurring anxiety.

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  33. Targeted de novo phasing and long-range assembly by template mutagenesis.

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  34. Predictive functional, statistical and structural analysis of CSNK2A1 and CSNK2B variants linked to neurodevelopmental diseases.

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  35. Exploring the symptom profiles of intolerance of uncertainty in autistic children.

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  36. Repeat polymorphisms in non-coding DNA underlie top genetic risk loci for glaucoma and colorectal cancer.

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  37. Differential Expression Analysis of Nothobranchius furzeri Transposable Elements from RNA-seq Data

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  38. A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations

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  39. Precision psychiatry requires disentangling disorder-specific variation: The case of ASD.

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  40. A Mildly Relativistic Outflow Launched Two Years after Disruption in the Tidal Disruption Event AT2018hyz

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    We present late-time radio/millimeter (as well as optical/UV and X-ray) detections of the tidal disruption event (TDE) AT2018hyz, spanning 970−1300 d after optical …

  41. A Generative Model for Quasar Spectra

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    We build a multi-output generative model for quasar spectra and the properties of their black hole engines, based on a Gaussian process latent-variable model. This model …

  42. A topological solution to object segmentation and tracking

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  43. Next-generation brain observatories

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  44. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

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  45. Structured random receptive fields enable informative sensory encodings

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  46. Flexible neural control of motor units

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    Voluntary movement requires communication from cortex to the spinal cord, where a dedicated pool of motor units (MUs) activates each muscle. The canonical description of MU function rests …

  47. A randomized controlled trial of everolimus for neurocognitive symptoms in PTEN hamartoma tumor syndrome.

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  48. ASD gene Bcl11a regulates subcellular RNA localization, associative circuitry, and social behavior.

    Publication