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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  • Simons Collaboration on Principles of Microbial Ecosystems
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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Biosensors and actuators for cellular and systems neuroscience

    Related
    This course will provide participants with an in-depth understanding of the principles behind the design and application of these tools, and enable hands-on experience with optogenetic …
  2. Machine Learning for Beginners Summer School

    Workshop
    The lectures (June) are especially meant for beginning machine learning practitioners. We provide a foundation in methods of Machine Learning but focus on its applications to real research …
  3. Sculpted Light in the Brain

    Related
    Sculpted Light in the Brain is a recurring conference (founded in 2017) aimed at fostering collaborations between neuroscientists, computer scientists, optics researchers, and other scientists who share the …
  4. Origins Space Telescope: Community Science Meeting

    Meeting
    … Galaxy Feedback and Outflows with Origins 2:30 – 3:00pm Chia-Yu Hu, Flatiron, Dust evolution in hydrodynamical simulations 3:00 – 3:30pm Break 3:30 – 4 …
  5. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  6. SCGB Boston-area Postdoc Meeting Series

    Event
    The Simons Collaboration on the Global Brain hosts a postdoc-focused Boston-area group meeting every other month to bring together postdocs interested in neural coding and dynamics …
  7. SFARI Viewer - an online platform to visualize and analyze SFARI genomic data

    Webinar
    On June 14, 2019, Alistair Ward and Chase Miller introduced SFARI Viewer and showed how this online platform can be used to visualize and analyze genomic and phenotypic …
  8. Machine Learning for Beginners Summer School

    Workshop
    The lectures (June) are especially meant for beginning machine learning practitioners. We provide a foundation in methods of Machine Learning but focus on its applications to real research …
  9. Roadmap to Fusion Energy Economy

    Event
    This event will bring in experts in innovative approaches to fusion, and possible pathways to a fusion economy. See more details on Stellar Energy Foundation’s webpage. Those …
  10. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  11. CCB Brown Bag Seminar

    Lecture
    Title: Towards automatically adaptive solvers for particulate Stokes flows in three dimensions The simulation of particulate flows plays a critical role in the design of microfluidic devices, the …
  12. FENS brain conference: Dynamics of the brain: temporal aspects of computation

    Related
    This conference will explore experimental and theoretical approaches to understand the underpinnings of neural dynamics and their relevance for computation in the brain.
  13. 2019 Many Electron Collaboration Summer School

    Conference
    … Carleo & Giacomo Torlai Machine Learning Methods I Hao Shi Auxiliary Field Quantum Monte Carlo II: ApplicationsView Slides Andrew Wray Resonant Inelastic X-Ray Scattering View Slides Instructor …
  14. CCB Colloquium: Katherine S. Pollard

    Colloquium
    Topic: A population genetic view of human chromatin organization Abstract: Genetic variation affects cellular and organismal biology through modifying genes and regulatory elements. But the degree to which …
  15. Machine Learning for Beginners Summer School

    Workshop
    The lectures (June) are especially meant for beginning machine learning practitioners. We provide a foundation in methods of Machine Learning but focus on its applications to real research …
  16. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  17. CCQ Quantum Cafe Schedule

    Lecture
    Quantum Café is CCQ’s ongoing seminar series: open to all bona fide members of the greater NYC scientific community and held every second week, Quantum Café presents …
  18. Transylvanian Experimental Neuroscience Summer School (TENSS) 2019

    Related
    TENSS concentrates top-level international expertise to teach a dozen students techniques and concepts in experimental systems neuroscience. We focus on modern optical and electrophysiological methods to study …
  19. CCQ Workshop Schedule

    Workshop
  20. WATCH: CCA Colloquium with Sara Ellison

    Colloquium
    Title: Galaxy mergers in the nearby Universe Abstract: Astronomy’s current model of galaxy evolution is built on a foundation of hierarchical growth, in which small galaxies merge …
  21. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  22. Simons Observatory Software Review+Hack meeting

    Meeting
  23. GRC: Modulation of neural circuits and behaviour

    Related
    Deep insights into neuromodulation are not only critical to understand the neural basis of intelligence and behavior but also to understand brain dysfunctions underlying disease. The conference will …
  24. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  25. CCQ Seminar: Tess Smidt

    Seminar
    Title: Tensor Field Networks: rotation-, translation-, and permutation-equivariant convolutional neural networks for 3D points Abstract: Atomic systems (molecules, crystals, proteins, nanoclusters, etc.) are naturally represented by a …
  26. QClub seminar: Lukas Muechler

    Seminar
    Speaker: Lukas Muechler (Flatiron Institute) Title: Topological Classification of Chemical Reactions Abstract: In this talk, we propose a topological classification of molecules and their chemical reactions with and …
  27. Theoretical and Computational Challenges in Planet Formation Workshop

    Workshop
    … Protostellar Disks: Dynamics & Diagnostics May 21, 2019 Giuseppe Lodato: Type II Migration in Planet Forming Discs May 21, 2019 Computational Discussion May 21, 2019 Joanna Drazkowska: Including …
  28. Algebraic, Complex and Arithmetic Dynamics (2019)

    Symposia
    … Mathematics Institute Patrick Ingram York University Mattias Jonsson University of Michigan Shu Kawaguchi Doshisha University Holly Krieger University of Cambridge John Lesieutre Pennsylvania State University Nicole Looper …
  29. Learning Fast Requires Good Memory: Time-Space Tradeoff Lower Bounds for Learning

    Lecture
    Can one prove unconditional lower bounds on the number of samples needed for learning, under memory constraints? A recent line of works shows that for a large class …
  30. Star Formation, Turbulence, Transport, and Feedback: Towards a Unified Model for the Dynamical State of Galactic Discs

    Lecture
    Abstract In this talk, I review attempts to build a self-consistent model for the dynamical state of the ISM in star-forming galactic discs. Ideally such a …
  31. Simons Collaboration on Algorithms & Geometry 2019 Annual Meeting

    Conference
    … quantitative version of this fact: every n x n complex matrix is within distance delta of a matrix whose eigenvectors have condition number poly(n)/delta, confirming …
  32. Cytotoxic T-cells and HIV: Can a Partially Effective Immune Response Be Improved to Cure Infection?

    Lecture
    Cytotoxic T-cells (CTL) represent an arm of the immune system that specializes in recognizing and eliminating virus-infected cells. In untreated infection, these cells play a critical …
  33. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  34. COSMOS Meeting

    Meeting
    We are pleased to announce the 2019 COSMOS Team Meeting to be held at the Flatiron Institute and hosted by the Computational Center for Astrophysics The meeting will …
  35. IQ-Collaboratory Meeting #6

    Meeting
    If you are interested in attending this event please email [email protected] Logistics Hotel Accommodations The Marcel At Gramercy Hotel 201 East 24th Street New York, NY …
  36. Neurodata Without Borders: Neurophysiology (NWB:N) User Days

    Related
    The NWB:N User Days will be devoted to helping users understand and adopt NWB:N, a data standard for neurophysiology that provides neuroscientists with a common standard …
  37. Amplitudes Meet Cosmology (2019)

    Symposia
    … Porto | Amplitudes Meet Classical Gravity (D) FRIDAY 10:00 – 11:00 AM Liam McAllister | Challenges in De Sitter (O) 11:30 – 12:30 PM Mina Arvanitaki & Dick …
  38. WATCH: CCA Special Colloquium with Megan Bedell

    Seminar
    May 10, 2019 Megan Bedell: Illuminating Stars and Their Planets with Precision Spectroscopy
  39. WATCH: CCA Colloquium with John Wise

    Colloquium
    May 10, 2019 John Wise: The First Stars, Black Holes, and Galaxies in the Universe
  40. Computational Data Analysis Class

    Meeting
    This is a semester-long informal class open to physics researchers in the NYC area. It is designed to help scientists with their data analysis projects. If you …
  41. SCGB West Coast Postdoc Meeting

    SCGB
    The Simons Collaboration on the Global Brain hosts a postdoc-focused Bay area group meeting every other month to bring together postdocs interested in neural coding and dynamics …
  42. Tensor Working Group

    Workshop
    The goal of this informal meeting will be to identify connections between disciplines which make use of tensor factorizations and decompositions. Speakers: Glen Evenbly, Georgia Tech Andrey Lokhov …
  43. Numerical Analysis Seminars

    Seminar
    Our seminar focuses on efficient computational methods for numerical problems, mostly phrased in a mathematical language, arising in areas of science throughout the Institute and beyond.
  44. CCB Colloquium: M. Lisa Manning

    Colloquium
    Title: The surprising impact of studying biological tissues as living materials Abstract: Your body is amazing. The instructions for its construction are encoded in only two cells, yet …
  45. Enzo-E Developer's Workshop

    Meeting
    Join organizer Greg Bryan for an informal meeting with the Enzo-E software project developers over three days to plan future work on this project. There will not …
  46. SCGB NY-Area Postdoc Meeting

    SCGB
    The Simons Collaboration on the Global Brain hosts a postdoc-focused NYC-area group meeting every other month to bring together postdocs interested in neural coding and dynamics …
  47. Common Envelope Evolution 2019 Workshop

    Workshop
    The aim of the workshop is to bring together some of the best scientists in the areas of common envelope evolution, to work together on novel ways to …
  48. New Directions in Theoretical Machine Learning (2019)

    Symposia
    … Slides FRIDAY 10:00 – 11:00 AM Ulrike Luxburg | Comparison-based Machine Learning Sham Kakade | Learning, Memory, and Entropy View Slides 11:30 – 12:30 PM Guy …
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