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May 19, 2025Announcing the awardees of Open Interval, a collaborative program for artists, scientists and arts organizations. -
In the NewsThe Perimeter Institute is like a concert hall where the deepest symphonies of nature are composed and performed.
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May 14, 2025In quantum physics, there’s no such thing as truly empty space. Even the barest of voids has quantum fluctuations, such as particles continually being created and quickly … -
May 13, 2025The documentary chronicles the ongoing quest to uncover the origins of the universe. -
May 13, 2025A healthy diet outperforms fecal transplants in restoring and protecting the gut microbiome, according to new research published in Nature by the Simons Foundation’s Joy Bergelson and … -
May 12, 2025SFARI will fund 18 meetings, with a focus on groups in the Simons Searchlight community, that bring together scientists and patient communities to share recent advancements and discuss … -
May 7, 2025SFARI is pleased to announce it will fund five projects investigating the influence of autism-associated risk genes on early neurodevelopment and links to later circuit-level functional … -
Funded WorkAutism spectrum disorder (ASD) is a neurodevelopmental condition with a strong genetic basis, but how genes contribute to abnormal circuit assembly remains unclear.
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May 7, 2025The National Academy of Sciences (NAS) has elected 150 new members to join its ranks. Among the inductees are 10 scientists who have served as Simons Foundation investigators … -
May 6, 2025The American Academy of Arts and Sciences (AAAS) recently named nearly 250 new members, including 11 scientists and mathematicians who have received funding from the Simons Foundation. The … -
New York PostThis year will be a big one for quantum computing, at least according to the United Nations: 2025 is officially the “International Year of Quantum Science and Technology …
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Funded WorkIn particle physics, the 10 TeV scale has emerged as the next target in the exploration of the energy frontier.
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Funded WorkThe Central American-Caribbean Bridge in Astrophysics (Cenca Bridge), an award-winning international nonprofit organization, provides opportunities to students from Central America and the Caribbean, where scientific research …
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May 1, 2025… region and raises awareness among local government funding agencies about the importance of supporting astronomy research. The MPS target grant will support Cenca Bridge’s three-month … -
April 30, 2025… team included researchers from the Technion-Israel Institute of Technology in Haifa, Israel; Queen Mary University of London and University College London; the University of Iowa in … -
April 30, 2025… National Magazine Award for Best Single-Topic Issue, and additional series are slated for later in the year. “We hope that these ambitious projects reflect the depth … -
April 29, 2025… high-resolution mapping of social behavior, this AI-driven approach offers new possibilities for studying autism and related neurodevelopmental disorders as well as identifying more precise interventions. -
April 29, 2025The International Congress of Basic Science has named Simons Fellow George Lusztig as one of this year’s recipients of its Basic Science Lifetime Award (BSLA) in Mathematics … -
The New York TimesThe cloud, named Eos, is chock-full of molecular hydrogen and possibly rife with star-forming potential in the future.
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April 29, 2025Flatiron Institute researchers have identified a previously unknown way to make the universe’s heaviest atoms, such as gold, platinum and uranium. They calculate that a single flare … -
April 25, 2025… “The Webb Space Telescope Will Rewrite Cosmic History. If It Works.” That piece was also a finalist for the National Magazine Award for Reporting. “This kind of … -
April 24, 2025The Simons Collaboration on Ecological Neuroscience (SCENE) is a 10-year program that will support projects aimed at uncovering how opportunities for action offered by the world shape … -
April 23, 2025On January 27–28, the Simons Foundation held the third annual meeting of the SFARI Sex Differences Collaboration (SSDC). Formed in 2021, this collaboration seeks to understand the … -
April 17, 2025A new study of zebra finches finds that levels of dopamine — a neurotransmitter that influences feelings of pleasure — fluctuate in the brains of adolescent birds as they learn … -
April 9, 2025Once home to inventor Lewis Latimer, this NYC museum now serves as a hub for informal STEAM education, inspiring young minds through hands-on learning and community programs. -
April 8, 2025The Simons Foundation Autism Research Initiative (SFARI) is pleased to announce the funding of 23 projects as part of its 2024 Pilot and Pilot Progression awards. Awards from … -
Funded WorkHypoxia-inducible factor (HIF), which consists of a labile HIFa subunit and stable HIFb (ARNT) subunit, is a master transcription factor that activates genes whose products promote adaptation …
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Funded WorkChanges in microglia, the immune cells of the brain, have been recognized in brain tissue of individuals with autism spectrum disorders (ASD) for over 15 years, but it …
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Funded WorkAutism can occur in isolation or as part of a syndrome which includes other neurodevelopmental disorders.
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Funded WorkAutism spectrum disorder (ASD) is a heritable neurodevelopmental condition marked by deficits in social communication.
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Funded WorkAutism spectrum disorders (ASDs) are associated with disruptions in the development and function of GABAergic neurons1, which are critical for maintaining the balance of excitation and inhibition in …
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Funded WorkWhile autism (ASD) is a heterogeneous disorder, a significant fraction of ASD genetic risk is conferred by genes encoding for relatively selective functions, including synaptic proteins, and regulators …
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Funded WorkProper brain function relies on the precise formation of neural circuits during development.
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Funded WorkAutism spectrum disorder (ASD) is associated with auditory hypersensitivity and auditory processing disorders.
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Funded WorkDysregulation of voltage-gated sodium channels (VGSC) is a prominent risk factor for autism spectrum disorder (ASD).
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Funded WorkAutism spectrum disorder (ASD) is a neurodevelopmental condition that is frequently characterized by movement disorders, including stereotyped repetitive hand movements, difficulties with gait, balance, and coordination, and delays …
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Funded WorkAutism spectrum disorder (ASD) is a neurodevelopmental disease that is frequently characterized by movement disorders, including stereotyped repetitive hand movements, difficulties with gait, balance, and coordination, and delays …
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Funded WorkNeurons derived from induced pluripotent stem cells (iPSCs) from individuals with autism offer the singular avenue to directly test novel therapeutic compounds for efficacy in treating autism spectrum …
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Funded WorkFragile X syndrome (FXS) is the most frequent monogenic cause of autism spectrum disorder (ASD).
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April 4, 2025The Division of Mathematics and Physical Sciences is pleased to announce the appointment of Bryna Kra, Ph.D. to the Scientific Advisory Board. Bryna Kra is the Sarah … -
Scientific AmericaOver the past decade, two very different ways of calculating the rate at which the universe is expanding have come to be at odds, a disagreement dubbed the …
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Funded WorkIndividuals with autism spectrum disorder (ASD) show varied phenotypes across social, communicative, sensory and motor domains.
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Funded WorkThere are hundreds of neurodevelopmental disorder (NDD) syndromes that cause autism because of the insufficient production of protein due to de novo mutations of specific genes.
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Funded WorkLarge-scale genetic studies have identified hundreds of genes associated with autism spectrum disorder (ASD).
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Funded WorkDifficulties with oromotor behaviors, like speech and feeding, are daily challenges for many individuals with autism.
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Funded WorkThe digestive distress that commonly accompanies autism spectrum disorder (ASD) significantly degrades the quality of life of those affected and their families1.
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Funded WorkAutism spectrum disorder (ASD) is often linked to mutations in genes regulating synaptic development and mRNA translation, implicating synaptic connectivity in its pathogenesis.
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Funded WorkAlternative splicing shows a unique profile in the brain and the dysregulation of alternative splicing networks has been repeatedly reported in autistic brains.