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Establishing a causal link between neural function and behavioral output has remained a challenging problem. Commonly used perturbation techniques enable unprecedented control over intrinsic activity patterns and can …

Neuropsychiatric disorders are often accompanied by cognitive impairments/intellectual disability (ID). It is not clear whether there are converging mechanisms underlying these debilitating impairments. We found that many …

The simplest scheme for predicting real galaxy properties after performing a dark matter simulation is to rank order the real systems by stellar mass and the simulated systems …

Accumulation of amyloid-β is a key neuropathological feature in brain of Alzheimer's disease patients. Alterations in cerebral haemodynamics, such as arterial impulse propagation driving the (peri …

The last two decades have established that a network of face-selective areas in the temporal lobe of macaque monkeys supports the visual processing of faces. Each area …

Anomalies among the daughter nuclei of the extinct short-lived radionuclides (SLRs) in the calcium-aluminum-rich inclusions (CAIs) indicate that the Solar System must have been born …

Phase retrieval is the inverse problem of recovering a signal from magnitude-only Fourier measurements, and underlies numerous imaging modalities, such as Coherent Diffraction Imaging (CDI). A variant …

Accretion disks around supermassive black holes in active galactic nuclei produce continuum radiation at ultraviolet and optical wavelengths. Physical processes in the accretion flow lead to stochastic variability …

In cellular vortical flows, namely arrays of counterrotating vortices, short but flexible filaments can show simple random walks through their stretch-coil interactions with flow stagnation points. Here …

As animals navigate on a two-dimensional surface, neurons in the medial entorhinal cortex (MEC) known as grid cells are activated when the animal passes through multiple locations …

There is a shortage of multiwavelength and spectroscopic follow-up capabilities given the number of transient and variable astrophysical events discovered through wide-field optical surveys such as …

The climbing fiber input to the cerebellum conveys instructive signals that can induce synaptic plasticity and learning by triggering complex spikes accompanied by large calcium transients in Purkinje …

Mixtures of microtubules and molecular motors form active materials with diverse dynamical behaviors that vary based on their constituents' molecular properties. We map the non-equilibrium phase diagram …

Animals face both external and internal dangers: pathogens threaten from the environment, and unstable genomic elements threaten from within. C. elegans protects itself from pathogens by "reading" bacterial …

Tubulin is a well-validated target for herbicides, fungicides, anti-parasitic, and anti-tumor drugs. Many of the non-cancer tubulin drugs bind to its colchicine site but …

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments …

The vast majority of Milky Way stellar halo stars were likely accreted from a small number (≲3) of relatively large dwarf galaxy accretion events. However, the timing of …

The vast majority of Milky Way stellar halo stars were likely accreted from a small number (≲3) of relatively large dwarf galaxy accretion events. However, the timing of …

Neutrophils are the most abundant human white blood cell and constitute a first line of defense in the innate immune response. Neutrophils are short-lived cells, and thus …

Predictive motion encoding is an important aspect of visually guided behavior that allows animals to estimate the trajectory of moving objects. Motion prediction is understood primarily in the …

Inference of action potentials ('spikes') from neuronal calcium signals is complicated by the scarcity of simultaneous measurements of action potentials and calcium signals ('ground truth'). In this study …

Interpreting the effects of genetic variants is key to understanding individual susceptibility to disease and designing personalized therapeutic approaches. Modern experimental technologies are enabling the generation of massive …

In order to ensure that analyses of complex electronic healthcare record (EHR) data are reproducible and generalizable, it is crucial for researchers to use comparable preprocessing, filtering, and …

Correlates of sensory stimuli and motor actions are found in multiple cortical areas, but such correlates do not indicate whether these areas are causally relevant to task performance …

Neurons in the medial entorhinal cortex alter their firing properties in response to environmental changes. This flexibility in neural coding is hypothesized to support navigation and memory by …