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  1. Autism-associated biomarkers: Test–retest reliability and relationship to quantitative social trait variation in rhesus monkeys.

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  2. Maternal steroid levels and the autistic traits of the mother and infant.

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  3. Age-Related Tau Burden and Cognitive Deficits Are Attenuated in KLOTHO KL-VS Heterozygotes

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  4. Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions

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  5. Inverse-Dirichlet Weighting Enables Reliable Training of Physics Informed Neural Networks

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    We characterize and remedy a failure mode that may arise from multi-scale dynamics with scale imbalances during training of deep neural networks, such as Physics Informed Neural …

  6. Atypical gaze patterns in autism are heterogeneous across subjects but reliable within individuals.

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  7. Multi-scale tensor network architecture for machine learning

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  8. Genetic signature of human longevity in PKC and NF-κB signaling

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    Gene variants associated with longevity are also associated with protection against cognitive decline, dementia and Alzheimer's disease, suggesting that common physiologic pathways act at the interface of …

  9. Mice in a labyrinth show rapid learning, sudden insight, and efficient exploration

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    Animals learn certain complex tasks remarkably fast, sometimes after a single experience. What behavioral algorithms support this efficiency? Many contemporary studies based on two-alternative-forced-choice (2AFC …

  10. A fast link between face perception and memory in the temporal pole

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    The question of how the brain recognizes the faces of familiar individuals has been important throughout the history of neuroscience. Cells linking visual processing to person memory have …

  11. A Bayesian approach for extracting free energy profiles from cryo-electron microscopy experiments using a path collective variable

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    Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature …

  12. Regression models for compositional data: General log-contrast formulations, proximal optimization, and microbiome data applications

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    Compositional data sets are ubiquitous in science, including geology, ecology, and microbiology. In microbiome research, compositional data primarily arise from high-throughput sequence-based profiling experiments. These data …

  13. Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.

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  14. Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders.

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  15. Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice

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  16. Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin.

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  17. Closing the species gap: Translational approaches to studying sensory processing differences relevant for autism spectrum disorder.

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  18. Autism symptoms in anorexia nervosa: A comparative study with females with autism spectrum disorder.

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  19. MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling

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  20. A neural circuit state change underlying skilled movements

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  21. A fast Chebyshev method for the Bingham closure with application to active nematic suspensions

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    Continuum kinetic theories provide an important tool for the analysis and simulation of particle suspensions. When those particles are anisotropic, the addition of a particle orientation vector to …

  22. Modularity and robustness of frontal cortical networks

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  23. Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging

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  24. How crosslink numbers shape the large-scale physics of cytoskeletal materials

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    Cytoskeletal networks are the main actuators of cellular mechanics, and a foundational example for active matter physics. In cytoskeletal networks, motion is generated on small scales by filaments …

  25. Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons.

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  26. Experiences and lessons learned from two virtual, hands-on microbiome bioinformatics workshops

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    In October of 2020, in response to the Coronavirus Disease 2019 (COVID-19) pandemic, our team hosted our first fully online workshop teaching the QIIME 2 microbiome bioinformatics …

  27. A causal view on compositional data

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    Many scientific datasets are compositional in nature. Important examples include species abundances in ecology, rock compositions in geology, topic compositions in large-scale text corpora, and sequencing count …

  28. Identifying developing interneurons as a potential target for multiple genetic autism risk factors in human and rodent forebrain.

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  29. Estimating genetic nurture with summary statistics of multi-generational genome-wide association studies.

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  30. Methods for analyzing neuronal structure and activity in Caenorhabditis elegans

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  31. Reflections on the genetics-first approach to advancements in molecular genetic and neurobiological research on neurodevelopmental disorders.

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  32. Representational geometry of perceptual decisions in the monkey parietal cortex

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  33. Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface

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  34. Geometry of abstract learned knowledge in the hippocampus

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  35. Visual intracortical and transthalamic pathways carry distinct information to cortical areas

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    Sensory processing involves information flow between neocortical areas, assumed to rely on direct intracortical projections. However, cortical areas may also communicate indirectly via higher-order nuclei in the …

  36. Sensorimotor strategies and neuronal representations for shape discrimination

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  37. Neuronal variability reflects probabilistic inference tuned to natural image statistics

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  38. Computational neuroimaging of cognition-emotion interactions: Affective and task-similar interference differentially impact working memory.

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  39. Microtubule reorganization during female meiosis in C. elegans

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    Most female meiotic spindles undergo striking morphological changes while transitioning from metaphase to anaphase. The ultra-structure of meiotic spindles, and how changes to this structure correlate with …

  40. Nonlinear Decoding of Natural Images From Large-Scale Primate Retinal Ganglion Recordings

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    Decoding sensory stimuli from neural activity can provide insight into how the nervous system might interpret the physical environment, and facilitates the development of brain-machine interfaces. Nevertheless …

  41. Oleic Acid Protects Caenorhabditis Mothers From Mating-Induced Death and the Cost of Reproduction

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  42. Internal state: dynamic, interconnected communication loops distributed across body, brain, and time

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  43. Unsupervised changes in core object recognition behavior are predicted by neural plasticity in inferior temporal cortex

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  44. Metallic Microswimmers Driven up the Wall by Gravity

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    Experiments on autophoretic bimetallic nanorods propelling within a fuel of hydrogen peroxide show that tail-heavy swimmers preferentially orient upwards and ascend along inclined planes. We show that …

  45. Representational drift in primary olfactory cortex

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  46. Diminished cortical excitation and elevated inhibition during perceptual impairments in a mouse model of autism.

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  47. Temporal integration of inductive cues on the way to gastrulation

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    In early development, cells commit to a single germ fate despite receiving multiple, conflicting inductive cues. Here, we examine how cells in the Drosophila embryo integrate promesodermal and …

  48. A Suite of Neurophotonic Tools to Underpin the Contribution of Internal Brain States in fMRI

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    Recent developments in optical microscopy, applicable for large-scale and longitudinal imaging of cortical activity in behaving animals, open unprecedented opportunities to gain a deeper understanding of neurovascular …