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  1. Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts.

    Publication

  2. Estimating the prevalence and genetic risk mechanisms of ARFID in a large autism cohort.

    Publication

  3. Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

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    Despite recent success in computational design of structured cyclic peptides, de novo design of cyclic peptides that bind to any protein functional site remains difficult. To address this …

  4. Single-particle excitations in the uniform electron gas by diagrammatic Monte Carlo

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    We calculate the single-particle excitation spectrum and the Landau liquid parameters for the three-dimensional uniform electron gas with a numerically exact variational diagrammatic Monte Carlo method …

  5. Neural basis of opioid-induced respiratory depression and its rescue.

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  6. The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating sonic hedgehog signalling.

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  7. The tectum/superior colliculus as the vertebrate solution for spatial sensory integration and action.

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  8. Genetic subtypes, allelic effects, and convergent neurodevelopmental mechanisms.

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  9. Psychometric validation and refinement of the Interoception Sensory Questionnaire (ISQ) in adolescents and adults on the autism spectrum.

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  10. The CHD8 CHD7/Kismet family links blood-brain barrier glia and serotonin to ASD-associated sleep defects

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  11. Inferring spikes from calcium imaging in dopamine neurons

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  12. Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature.

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  13. A Tale of Two Grains: Impact of Grain Size on Ring Formation via Nonideal Magnetohydrodynamic Processes

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    Substructures in PPDs, whose ubiquity was unveiled by recent ALMA observations, are widely discussed regarding their possible origins. We carry out global full magnetohydrodynamic (MHD) simulations in axisymmetry …

  14. Collicular circuits for flexible sensorimotor routing

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  15. Axisymmetric membranes with edges under external force: buckling, minimal surfaces, and tethers

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    We use theory and numerical computation to determine the shape of an axisymmetric fluid membrane with a resistance to bending and constant area. The membrane connects two rings …

  16. Mesoscale cortical dynamics reflect the interaction of sensory evidence and temporal expectation during perceptual decision-making

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  17. Chronic, cortex-wide imaging of specific cell populations during behavior

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  18. Improving scalability in systems neuroscience

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  19. 16p11.2 deletion syndrome.

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  20. Patterns and correlates of two-year changes in depressive symptoms for autistic adults.

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  21. Structural and functional brain alterations revealed by neuroimaging in CNV carriers.

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  22. Dynamical correlation energy of metals in large basis sets from downfolding and composite approaches

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  23. Momentum-space signatures of Berry flux monopoles in the Weyl semimetal TaAs

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  24. A magnon scattering platform

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  25. A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations

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  26. Thalamic control of cortical dynamics in a model of flexible motor sequencing

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  27. Identification of multiple noise sources improves estimation of neural responses across stimulus conditions

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  28. Prevalence of returnable genetic results based on recognizable phenotypes among children with autism spectrum disorder.

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  29. CNVxplorer: A web tool to assist clinical interpretation of CNVs in rare disease patients.

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  30. Sex-specific stress-related behavioral phenotypes and central amygdala dysfunction in a mouse model of 16p11.2 microdeletion.

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  31. FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currents.

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  32. Robust and replicable measurement for prepulse inhibition of the acoustic startle response.

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  33. Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability.

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  34. Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior.

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  35. Resting and functional pupil response metrics indicate features of reward sensitivity and ASD in children.

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  36. Adaptive behavior profiles of intellectually gifted children with autism spectrum disorder.

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  37. Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia.

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  38. A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders.

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  39. Rank-normalization, folding, and localization: An improved \(R\) for assessing convergence of MCMC

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    Markov chain Monte Carlo is a key computational tool in Bayesian statistics, but it can be challenging to monitor the convergence of an iterative stochastic algorithm. In this …

  40. Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter.

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  41. Adaptive Monte Carlo augmented with normalizing flows

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    Many problems in the physical sciences, machine learning, and statistical inference necessitate sampling from a high-dimensional, multi-modal probability distribution. Markov Chain Monte Carlo (MCMC) algorithms, the …

  42. Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures.

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  43. Atlas of functional connectivity relationships across rare and common genetic variants, traits, and psychiatric conditions.

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  44. Relationship between social motivation in children with autism spectrum disorder and their parents.

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  45. Place-cell capacity and volatility with grid-like inputs

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    What factors constrain the arrangement of the multiple fields of a place cell? By modeling place cells as perceptrons that act on multiscale periodic grid-cell inputs, we …

  46. Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity.

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  47. Association of CDH11 with ASD revealed by matched-gene co-expression analysis and mouse behavioral studies.

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  48. Calibration of the Hα Age–Activity Relation for M Dwarfs

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    In this work, we calibrate the relationship between Halpha emission and M dwarf ages. We compile a sample of 892 M dwarfs with Halpha equivalent width (HaEW) measurements …