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  1. Chemodynamically Characterizing the Jhelum Stellar Stream with APOGEE-2

    Publication
    We present the kinematic and chemical profiles of red giant stars observed by the APOGEE-2 survey in the direction of the Jhelum stellar stream, a Milky Way …

  2. cuFINUFFT: a load-balanced GPU library for general-purpose nonuniform FFTs

    Publication
    Nonuniform fast Fourier transforms dominate the computational cost in many applications including image reconstruction and signal processing. We thus present a general-purpose GPU-based CUDA library for …

  3. Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer's Disease

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  4. Standardized and reproducible measurement of decision-making in mice

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    Progress in science requires standardized assays whose results can be readily shared, compared, and reproduced across laboratories. Reproducibility, however, has been a concern in neuroscience, particularly for measurements …

  5. Altered maturation and atypical cortical processing of spoken sentences in autism spectrum disorder.

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  6. A Stellar Activity F-statistic for Exoplanet Surveys (SAFE)

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    In the search for planets orbiting distant stars the presence of stellar activity in the atmospheres of observed stars can obscure the radial velocity signal used to detect …

  7. Accelerating diagnosis of Parkinson's disease through risk prediction

    Publication

  8. Accelerating diagnosis of Parkinson's disease through risk prediction

    Publication
    Background: Characterization of prediagnostic Parkinson's Disease (PD) and early prediction of subsequent development are critical for preventive interventions, risk stratification and understanding of disease pathology. This study …

  9. A method to delineate de novo missense variants across pathways prioritizes genes linked to autism.

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  10. COVID-19 health and social care access for autistic people: European policy review.

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  11. Genomic selection signatures in autism spectrum disorder identifies cognitive genomic tradeoff and its relevance in paradoxical phenotypes of deficits versus potentialities.

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  12. Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry.

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  13. CMB lensing power spectrum estimation without instrument noise bias

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    The power spectrum of cosmic microwave background (CMB) lensing will be measured to sub-percent precision with upcoming surveys, enabling tight constraints on the sum of neutrino masses …

  14. Bayonet-shaped language development in autism with regression: A retrospective study.

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  15. AI-assisted super-resolution cosmological simulations

    Publication
    Cosmological simulations of galaxy formation are limited by finite computational resources. We draw from the ongoing rapid advances in Artificial Intelligence (specifically Deep Learning) to address this problem …

  16. Single nucleus multi-omics regulatory atlas of the murine pituitary

    Publication
    To provide a multi-omics resource and investigate transcriptional regulatory mechanisms, we profile the transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from …

  17. Individuals with autism spectrum disorder have altered visual encoding capacity.

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  18. High-performance brain-to-text communication via handwriting

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    Brain-computer interfaces (BCIs) can restore communication to people who have lost the ability to move or speak. So far, a major focus of BCI research has been …

  19. Recovering missing data in coherent diffraction imaging

    Publication
    In coherent diffraction imaging (CDI) experiments, the intensity of the scattered wave impinging on an object is measured on an array of detectors. This signal can be interpreted …

  20. A unified resource and configurable model of the synapse proteome and its role in disease.

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  21. Broad frequency sensitivity and complex neural coding in the larval zebrafish auditory system.

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  22. Chandelier cartridge density is reduced in the prefrontal cortex in autism.

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  23. Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data.

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  24. Optimising a simple fully convolutional network for accurate brain age prediction in the PAC 2019 challenge.

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  25. Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH.

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  26. Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections.

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  27. An investigation of the diet, exercise, sleep, BMI, and health outcomes of autistic adults.

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  28. Sex and death

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    Sexual interactions negatively impact health and longevity in many species across the animal kingdom. C. elegans has been established as a good model to study how mating and …

  29. Rhesus monkeys as a translational model for late-onset Alzheimer's disease

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    Age is a major risk factor for late-onset Alzheimer's disease (AD) but seldom features in laboratory models of the disease. Furthermore, heterogeneity in size and density …

  30. Fluid Transport in the Brain

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    Brain harbors a unique ability to, figuratively speaking, shift its gears. During wakefulness, the brain is geared fully towards processing information and behaving, while homeostatic functions predominate during …

  31. AI-assisted superresolution cosmological simulations

    Publication
    Cosmological simulations of galaxy formation are limited by finite computational resources. We draw from the ongoing rapid advances in Artificial Intelligence (specifically Deep Learning) to address this problem …

  32. Pinpointing the neural signatures of single-exposure visual recognition memory

    Publication
    Memories of the images that we have seen are thought to be reflected in the reduction of neural responses in high-level visual areas such as inferotemporal (IT …

  33. Pinpointing the neural signatures of single-exposure visual recognition memory

    Publication
    Memories of the images that we have seen are thought to be reflected in the reduction of neural responses in high-level visual areas such as inferotemporal (IT …

  34. Single-cell gene regulatory network inference at scale: The Inferelator 3.0

    Publication
    Gene regulatory networks define regulatory relationships between transcription factors and target genes within a biological system, and reconstructing them is essential for understanding cellular growth and function. In …

  35. Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: A genetically informed approach.

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  36. AI-assisted super-resolution cosmological simulations II: Halo substructures, velocities and higher order statistics

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  37. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop

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    A hallmark of aging is immunosenescence, a decline in immune functions, which appeared to be inevitable in living organisms, including Caenorhabditis elegans. Here, we show that genetic inhibition …

  38. Age-related telomere attrition causes aberrant gene expression in sub-telomeric regions

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    Telomere attrition has been proposed as a biomarker and causal factor in aging. In addition to causing cellular senescence and apoptosis, telomere shortening has been found to affect …

  39. Discovery of autism/intellectual disability somatic mutations in Alzheimer's brains: mutated ADNP cytoskeletal impairments and repair as a case study

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  40. Assessing child postural variability: Development, feasibility, and reliability of a video coding system.

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  41. A hydraulic instability drives the cell death decision in the nematode germline

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    Oocytes are large cells that develop into an embryo upon fertilization1. As interconnected germ cells mature into oocytes, some of them grow—typically at the expense of others …

  42. Muonium hydride: The lowest density crystal

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  43. Simulations of Trions and Biexcitons in Layered Hybrid Organic-Inorganic Lead Halide Perovskites

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  44. Optimal control for quantum metrology via Pontryagin’s principle

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  45. Designing and controlling the properties of transition metal oxide quantum materials

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    This Perspective addresses the design, creation, characterization and control of synthetic quantum materials with strong electronic correlations. We show how emerging synergies between theoretical/computational approaches and materials …

  46. Dependence of DFT+DMFT results on the construction of the correlated orbitals

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  47. Generation of fate patterns via intercellular forces.

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  48. A stable and accurate scheme for solving the Stefan problem coupled with natural convection using the Immersed Boundary Smooth Extension method

    Publication
    In cellular vortical flows, short but flexible filaments can show simple random walks through their stretch-coil interactions with flow stagnation points. Here, we study the dynamics of …