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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. New Satellite Will Help NASA Keep PACE with Earth Systems

    Eos
    On 6 February, NASA plans to launch a new satellite tasked with monitoring microbes in the ocean and aerosols in the atmosphere. The mission, called PACE (Plankton, Aerosol …
  2. Simons Investigators Elected to American Academy of Microbiology

    February 16, 2024
    Simons Investigators in Aquatic Microbial Ecology Brett Baker and Alyson Santoro have been elected to the American Academy of Microbiology. The honor is “based on their records of …
  3. BIOS-SCOPE Collaboration Investigator Elizabeth B. Kujawinski Wins G. Evelyn Hutchinson Award

    February 15, 2024
    The Association for the Sciences of Limnology and Oceanography has named oceanographer Elizabeth B. Kujawinski the winner of the 2024 Evelyn Hutchinson Award. The honor recognizes mid-career …
  4. Math as a Bridge to Endless Opportunity

    February 14, 2024
    How Bridge to Enter Advanced Mathematics prepares curious, talented young people to become the next generation of STEM practitioners.
  5. Saturn’s ‘Death Star’ Moon Might Contain a Hidden Ocean

    Science News
    An uncanny resemblance to the Death Star might not be the only intriguing thing about Saturn’s moon Mimas. It could also harbor a vast ocean of liquid …
  6. Simons Foundation Funds More Than 100 Events for April Solar Eclipse

    February 7, 2024
    The foundation’s In the Path of Totality initiative is partnering with dozens of communities to make the upcoming eclipse an engaging and unforgettable experience.
  7. Ecosystem on the edge: How coastal marsh plants and microbes thrive in an oscillating environment

    Funded Work
  8. A Moving Target for Quantum Advantage

    Physics
    Researchers have used quantum computers to solve difficult physics problems. But claims of a quantum “advantage” must wait as ever-improving algorithms boost the performance of classical computers.
  9. CCB Flatiron Research Fellow Miro Astore Awarded Young Biophysicist Award

    January 26, 2024
    Last month, Flatiron Institute postdoc Miro Astore received the Young Biophysicist Award at the 47th Annual Conference of the Australian Society for Biophysics. The award was established in …
  10. Quanta Magazine Partners With PRX and Cosmologist Janna Levin for Season 3 of ‘The Joy of Why’ Podcast

    January 25, 2024
    … received a National Academies Eric and Wendy Schmidt Award for Excellence in Science Communications partly for his work on “The Joy of Why.” Celebrating more than 20 …
  11. Charting a New Course Through the Injured Brain

    The Scientist
    A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.
  12. 2023 SFARI Human Cognitive and Behavioral Science Awardees Announced

    January 23, 2024
    SFARI is pleased to announce that it intends to fund three grants in response to the 2023 Human Cognitive and Behavioral Science request for applications.
  13. Introducing The Triangle Program, Making Space for Artists and Scientists To Collaborate

    January 22, 2024
    … before proposing a project. During the planning phase, we provided starter grants and support to catalyze conversations around art, science, cross-pollination and the upcoming solar eclipse …
  14. Simons Searchlight December 2023 Update: New Phenotypic Data Available

    January 19, 2024
    New phenotypic data from Simons Searchlight participants were recently added to SFARI Base. This release includes data from individuals with 94 gene changes and 15 copy number variants …
  15. 2023 SFARI Cross-Species Studies of ASD Awardees Announced

    January 18, 2024
    SFARI is pleased to announce that it intends to fund three collaborative projects in response to the 2023 Cross-Species Studies of ASD request for applications.
  16. New Battery Material That Uses Less Lithium Found in AI-Powered Search

    The Washington Post
    Microsoft announced Tuesday that a team of scientists used artificial intelligence and high-performance computing to plow through 32.6 million possible battery materials ― many not found in …
  17. CUNY to Receive $75 Million Donation to Boost Tech Programs

    Inside Higher Ed
  18. Viviana Acquaviva Wins Chambliss Astronomical Writing Award

    AAS
    The Chambliss Astronomical Writing Award is presented for astronomy writing for an academic audience — specifically, textbooks at either the upper-division undergraduate or the graduate level.
  19. Venus’ Clouds Have a UV Secret. Scientists Might Have Cracked It

    Cosmos Magazine
    New research suggests that two iron-bearing sulphate materials called rhomboclase and acid ferric sulphate could help explain patches and streaks in the clouds around Venus visible in …
  20. Integrated anatomical and gene expression phenotyping in mouse models of autism

    Funded Work
    Genetic disruption of gene-regulatory proteins has emerged as a major underlying cause of autism and related neurodevelopmental disorders (ASD/NDD).
  21. Functionally characterizing genetic variants in the activation domains of autism-associated transcription factors

    Funded Work
    There has been tremendous progress in identifying the genetic basis of autism spectrum disorder (ASD).
  22. Real-time tracking and control of brain neuropeptide levels in a mouse model of autism

    Funded Work
    Dysregulated levels of neuromodulators and other chemical signals may contribute to behavioral characteristics of autism spectrum disorder (ASD).
  23. Empire AI Consortium to Make New York the National Leader in AI Research and Innovation

    Office of the Governor of New York
  24. Life Beyond Earth May Form in the Coldest Depths of Space, Ryugu Asteroid Samples Reveal

    Space.com
    In 2020, the Japanese spacecraft Hayabusa2 visited the asteroid Ryugu and managed to bring precious samples of the space rock back to Earth. And sure enough, years later …
  25. The Quantum Phantom

    Science
    A ghostly quasiparticle rooted in a century-old Italian mystery could unlock quantum computing’s potential—if only it could be pinned down.
  26. Hints of Elegance in the Physics Governing Snowfall

    Physics Today
    For atmospheric scientists, snowflake morphology helps determine how the flakes descend through the turbulent atmosphere. Now, using a custom-made snowflake-tracking apparatus installed at a ski resort …
  27. Together, Math and Science Foundations Fund ‘Tabletop’ Physics That Could Transform Our Understanding of the Universe

    December 11, 2023
    … the assumption that gravity works in the same way from macroscopic scales all the way down to the submicron level. Jason Hogan of Stanford University will lead …
  28. All Five Flatiron Centers Represented at the Conference on Neural Information Processing Systems (NeurIPS)

    December 8, 2023
    For the first time, the five Flatiron Institute research centers (astrophysics, biology, mathematics, neuroscience and quantum physics), as well as its Scientific Computing Core and the Foundation Models …
  29. Quantitative motor phenotyping in nonsyndromic autism and chromatin modifying disorders

    Funded Work
    Delayed or impaired motor development can detrimentally affect environmental exploration, social engagement and spatial perception.
  30. New Astrophysics Model Sheds Light on Additional Source of Long Gamma-Ray Bursts

    November 29, 2023
    Using state-of-the-art computer simulations, astrophysicists at the Flatiron Institute and their colleagues have sharpened our picture of how black holes may generate some of the …
  31. Black Girls Dive Foundation

    Funded Work
    Organization that establishes space and opportunity to empower young ladies to explore their STEM identity through marine science and conservation, and SCUBA diving.
  32. Whiteswan Environmental

    Funded Work
    Native-led non-profit educating and strengthening relationships between bio-regional native and non-native government and NGO’s, as well as academic institutions to reconnect Coast Salish …
  33. The epitranscriptome in the maternal immune activation model of neurodevelopmental conditions

    Funded Work
    Environmental perturbations that disrupt fetal neurodevelopment are strongly associated with autism spectrum disorder (ASD).
  34. Diversity and persistence in plankton communities: Linking models and observations of taxa and trait dynamics

    Funded Work
  35. New Neuroscience Publication, The Transmitter, Will Inform and Connect the Field

    November 13, 2023
    … to map out — neuron by neuron — how individual insects respond to an imaginary predator; and a photo gallery of people with early-onset Alzheimer’s disease describing …
  36. SCGB Presentations at the 2023 Society for Neuroscience Conference

    November 10, 2023
    Check out these presentations from SCGB PIs and trainees at the SFN conference November on 11-15.
  37. Two Studies Using Brain Organoids Reveal Cell-Type-Specific Changes During the Early Stages of Human Forebrain Neuronal Development in Autism

    November 9, 2023
    Two studies by different research groups — one led by Flora Vaccarino and the other by Juergen Knoblich — used brain organoids derived from pluripotent stem cells of people with …
  38. Two SFARI Investigators Elected to the National Academy of Medicine

    November 9, 2023
    This year’s new cohort of National Academy of Medicine members includes two investigators funded by the Simons Foundation Autism Research Initiative (SFARI). Election to the academy “recognizes …
  39. SCPAB Presentations at the 2023 Society for Neuroscience Conference

    November 9, 2023
    Check out these presentations from SCPAB PIs and trainees at the SFN conference on November 11-15.
  40. New York Climate Exchange Selects Stephen Hammer as First CEO

    November 9, 2023
    … International and Public Affairs, and the Pratt Institute, where he specialized in urban energy systems and policy, often focusing on New York City. He also co-founded …
  41. Independence Fellow Abhilasha Joshi Receives Peter and Patricia Gruber International Research Award

    November 8, 2023
    The Society for Neuroscience has awarded neuroscientist Abhilasha Joshi its Peter and Patricia Gruber International Research Award, which recognizes “young neuroscientists for outstanding research and educational pursuit in …
  42. Experiments and Mathematical Model Uncover the Mechanisms Behind Wrinkles in Cell Nuclei

    November 3, 2023
    By studying the changing geometry of cell nuclei in fruit flies, scientists have gained a better understanding of the dynamics that shape the part of our cells that …
  43. Quanta Magazine and Simons Foundation Writers Win 3 Awards for Excellence in Science Communications

    November 2, 2023
    … independent publication launched by the Simons Foundation to illuminate big ideas in science and math through public service journalism. Quanta’s reporters and editors focus on developments …
  44. Mathematician Rachel Ward Sees the Big Picture

    November 2, 2023
    By extracting ideas from different fields and applying them to broad problems, Rachel Ward has built unexpected connections across a huge swath of applied mathematics.
  45. Evolution of the Nervous System

    Knowable Magazine
    When, why and how did neurons first evolve? Scientists are piecing together the ancient story.
  46. Neuroscience 2023: Presentations by SFARI Investigators

    October 31, 2023
    A number of presentations will be given by SFARI Investigators at Neuroscience 2023, the annual meeting of the Society for Neuroscience.
  47. Annotation of the synaptic interactome and synaptic pathways relevant for autism

    Funded Work
    Large-scale genetic studies are producing valuable new leads to understand disease mechanisms and identify new treatment targets.
  48. Computational phenotyping of individual variation in latent-state learning, generalization and attention across the autism spectrum

    Funded Work
    People with autism spectrum disorder (ASD) often exhibit rigid patterns of behavior, manifesting as difficulty generalizing when encountering a new example of something known or something known in …
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