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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. EMPress Enables Tree-Guided, Interactive, and Exploratory Analyses of Multi-omic Data Sets

    Publication
    Standard workflows for analyzing microbiomes often include the creation and curation of phylogenetic trees. Here we present EMPress, an interactive web tool for visualizing trees in the context …
  2. Alternating sources of perisomatic inhibition during behavior.

    Publication
  3. The Atacama Cosmology Telescope: Combined kinematic and thermal Sunyaev-Zel'dovich measurements from BOSS CMASS and LOWZ halos

    Publication
    The scattering of cosmic microwave background (CMB) photons off the free-electron gas in galaxies and clusters leaves detectable imprints on high resolution CMB maps: the thermal and …
  4. The Atacama Cosmology Telescope: Modeling the Gas Thermodynamics in BOSS CMASS galaxies from Kinematic and Thermal Sunyaev-Zel'dovich Measurements

    Publication
    The thermal and kinematic Sunyaev-Zel'dovich effects (tSZ, kSZ) probe the thermodynamic properties of the circumgalactic and intracluster medium (CGM and ICM) of galaxies, groups, and clusters …
  5. Planckian Metal at a Doping-Induced Quantum Critical Point

    Publication
    We numerically study a model of interacting spin-\(1/2\) electrons with random exchange coupling on a fully connected lattice. This model hosts a quantum critical point separating …
  6. An automated framework for efficiently designing deep convolutional neural networks in genomics

    Publication
    Convolutional neural networks (CNNs) have become a standard for analysis of biological sequences. Tuning of network architectures is essential for a CNN’s performance, yet it requires substantial …
  7. Bacterial activity hinders particle sedimentation

    Publication
    Sedimentation in active fluids has come into focus due to the ubiquity of swimming micro-organisms in natural and industrial processes. Here, we investigate sedimentation dynamics of passive …
  8. Sex differences in brain development in fetuses and infants who are at low or high likelihood for autism.

    Publication
  9. Synaptic plasticity as Bayesian inference

    Publication
    Learning, especially rapid learning, is critical for survival. However, learning is hard; a large number of synaptic weights must be set based on noisy, often ambiguous, sensory information …
  10. Protocol for transgenerational learned pathogen avoidance behavior assays in Caenorhabditis elegans

    Publication
    Animal experiences, including learned behaviors, can be passed down to several generations of progeny in a phenomenon known as transgenerational epigenetic inheritance. Yet, little is known regarding the …
  11. More data or more parameters? Investigating the effect of data structure on generalization

    Publication
    One of the central features of deep learning is the generalization abilities of neural networks, which seem to improve relentlessly with over-parametrization. In this work, we investigate …
  12. Children with autism spectrum disorder show altered functional connectivity and abnormal maturation trajectories in response to inverted faces.

    Publication
  13. BARcode DEmixing through Non-negative Spatial Regression (BarDensr)

    Publication
    Modern spatial transcriptomics methods can target thousands of different types of RNA transcripts in a single slice of tissue. Many biological applications demand a high spatial density of …
  14. Functional genomics of inflamm-aging and immunosenescence

    Publication
    The aging population is at a higher risk for age-related diseases and infections. This observation could be due to immunosenescence: the decline in immune efficacy of both …
  15. Limited Evidence for Sensory Prediction Error Responses in Visual Cortex of Macaques and Humans

    Publication
    A recent formulation of predictive coding theory proposes that a subset of neurons in each cortical area encodes sensory prediction errors, the difference between predictions relayed from higher …
  16. Transcriptome analysis reveals the difference between "healthy" and "common" aging and their connection with age-related diseases

    Publication
    A key goal of aging research was to understand mechanisms underlying healthy aging and develop methods to promote the human healthspan. One approach is to identify gene regulations …
  17. Enhanced tunable second harmonic generation from twistable interfaces and vertical superlattices in boron nitride homostructures

    Publication
    Broken symmetries induce strong even-order nonlinear optical responses in materials and at interfaces. Unlike conventional covalently bonded nonlinear crystals, van der Waals (vdW) heterostructures feature layers that …
  18. A Decade of Radial-velocity Monitoring of Vega and New Limits on the Presence of Planets

    Publication
    We present an analysis of 1524 spectra of Vega spanning 10 years, in which we search for periodic radial velocity variations. A signal with a periodicity of 0 …
  19. Autobahn: Automorphism-based Graph Neural Nets

    Publication
  20. A new ionisation network and radiation transport module in PLUTO

    Publication
    We introduce a new general-purpose time-dependent ionisation network (IN) and a radiation transport (RT) module in the magneto-hydrodynamic (MHD) code PLUTO. Our ionisation network is …
  21. Constrained-path auxiliary-field quantum Monte Carlo for coupled electrons and phonons

    Publication
  22. Improving the measurement of alexithymia in autistic adults: A psychometric investigation and refinement of the twenty-item Toronto Alexithymia Scale.

    Publication
  23. Aliasing error of the exp \(β\sqrt{1-z^2}\) kernel in the nonuniform fast Fourier transform

    Publication
    The most popular algorithm for the nonuniform fast Fourier transform (NUFFT) uses the dilation of a kernel \(phi\) to spread (or interpolate) between given nonuniform points and a …
  24. Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism.

    Publication
  25. BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex.

    Publication
  26. Towards robust and replicable sex differences in the intrinsic brain function of autism.

    Publication
  27. The emerging role of chromatin remodelers in neurodevelopmental disorders: A developmental perspective.

    Publication
  28. Elevated polygenic burden for autism spectrum disorder is associated with the broad autism phenotype in mothers of individuals with autism spectrum disorder.

    Publication
  29. AMBIENT: Accelerated Convolutional Neural Network Architecture Search for Regulatory Genomics

    Publication
    Convolutional neural networks (CNN) have become a standard approach for modeling genomic sequences. CNNs can be effectively built by Neural Architecture Search (NAS) by trading computing power for …
  30. An unsupervised method for identifying X-enriched stars directly from spectra: Li in LAMOST

    Publication
    Stars with peculiar element abundances are important markers of chemical enrichment mechanisms. We present a simple method, tangent space projection (TSP), for the detection of X-enriched stars …
  31. A fully kinetic model for orphan gamma-ray flares in blazars

    Publication
    Blazars emit a highly variable non-thermal spectrum. It is usually assumed that the same non-thermal electrons are responsible for the IR-optical-UV emission (via synchrotron …
  32. Can Galaxy Evolution Mimic Cosmic Reionization?

    Publication
    Lyman-α (Lyα) emitting galaxies are powerful tools to probe the late stages of cosmic reionization. The observed sudden drop in Lyα fraction at z>6 is often …
  33. Checkpointing with cp: the POSIX Shared Memory System

    Publication
    We present the checkpointing scheme of Abacus, an N-body simulation code that allocates all persistent state in POSIX shared memory, or ramdisk. Checkpointing becomes as simple as …
  34. A randomization-based causal inference framework for uncovering environmental exposure effects on human gut microbiota

    Publication
    Statistical analysis of microbial genomic data within epidemiological cohort studies holds the promise to assess the influence of environmental exposures on both the host and the host-associated …
  35. Alfvén wave mode conversion in pulsar magnetospheres

    Publication
    The radio emission anomaly coincident with the 2016 glitch of the Vela pulsar may be caused by a star quake that launches Alfvén waves into the magnetosphere, disturbing …
  36. Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases

    Publication
    A key goal of geroscience research is to identify effective interventions to extend human healthspan, the years of healthy life. Currently, majority of the geroprotectors are found by …
  37. Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development.

    Publication
  38. Nonlinear convergence boosts information coding in circuits with parallel outputs

    Publication
    Neural circuits are structured with layers of converging and diverging connectivity and selectivity-inducing nonlinearities at neurons and synapses. These components have the potential to hamper an accurate …
  39. Mechanical Mechanisms of Chromosome Segregation

    Publication
    Chromosome segregation—the partitioning of genetic material into two daughter cells—is one of the most crucial processes in cell division. In all Eukaryotes, chromosome segregation is driven …
  40. Mechanical Mechanisms of Chromosome Segregation

    Publication
    Chromosome segregation—the partitioning of genetic material into two daughter cells—is one of the most crucial processes in cell division. In all Eukaryotes, chromosome segregation is driven …
  41. Independent generation of sequence elements by motor cortex

    Publication
    Rapid execution of motor sequences is believed to depend on fusing movement elements into cohesive units that are executed holistically. We sought to determine the contribution of primary …
  42. Distributed chromatic processing at the interface between retina and brain in the larval zebrafish

    Publication
    Larval zebrafish (Danio rerio) are an ideal organism for studying color vision, as their retina possesses four types of cone photoreceptors, covering most of the visible range and …
  43. Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids.

    Publication
  44. Topography in the Bursting Dynamics of Entorhinal Neurons

    Publication
    Medial entorhinal cortex contains neural substrates for representing space. These substrates include grid cells that fire in repeating locations and increase in scale progressively along the dorsal-to …
  45. CARPool: fast, accurate computation of large-scale structure statistics by pairing costly and cheap cosmological simulations

    Publication
    To exploit the power of next-generation large-scale structure surveys, ensembles of numerical simulations are necessary to give accurate theoretical predictions of the statistics of observables. High …
  46. Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years

    Publication
    Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that …
  47. Cell-to-cell variation in gene expression and the aging process

    Publication
    There is tremendous variation in biological traits, and much of it is not accounted for by variation in DNA sequence, including human diseases and lifespan. Emerging evidence points …
  48. Extracting the dynamics of behavior in sensory decision-making experiments

    Publication
    Decision-making strategies evolve during training and can continue to vary even in well-trained animals. However, studies of sensory decision-making tend to characterize behavior in terms …
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