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May 6, 2022Sitting at the juncture of quantum physics and fluid dynamics, Flatiron Institute physicist Nikita Kavokine has been called a “quantum plumber” for having discovered the specifics of how … -
May 3, 2022For the first time, the community of Science Sandbox awardees convened for a two-day summit at the Simons Foundation -
May 2, 2022… Powers and The Joy of x. Quanta Magazine is an award-winning, editorially independent publication launched by the Simons Foundation to illuminate big ideas in science and … -
Funded WorkAs we age, most individuals will experience normal declines in cognitive abilities, including memory. -
April 29, 2022Ian Lipkin, Mady Hornig and colleagues showed that levels of immune molecules in mothers during pregnancy and in cord blood at birth are highly predictive of later autism … -
April 29, 2022Laura Andreae, M. Albert Basson and collaborators showed that Chd8 haploinsufficiency in mice was linked to changes in excitation/inhibition balance and disrupted homeostatic plasticity of prefrontal circuits.
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April 29, 2022SFARI is pleased to announce that it intends to fund seven grants in response to the Autism Rat Models Consortium request for applications. -
April 29, 2022SFARI Investigator Susanne Schmid and colleagues showed that loss of Cntnap2 in rats leads to immature-like delays in auditory cortex sound processing and overactive auditory neurons.
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April 28, 2022Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
April 28, 2022Massive neural recordings combined with advanced analyses can distill insight from enigmatic data. How far can these tools take us? -
April 27, 2022Sometimes computer crashes occur because a computer program looks for something that no longer exists. This is a problem that Simons Junior Fellow Sebastian Wolff wants to solve. -
April 26, 2022Autism BrainNet announces the recipients of the 2022 Autism BrainNet Appreciation Award, an initiative that recognizes outstanding partners and collaborators for their dedication to advancing brain tissue research … -
April 19, 2022A joint project of the Foundation for Angelman Syndrome Therapeutics (FAST) and SFARI, the International Angelman Syndrome Research Council (INSYNC-AS) held its inaugural meeting on July 9 … -
April 19, 2022At the intersection of neuroscience, computer science and theoretical physics, Flatiron Institute neuroscientist SueYeon Chung is working to understand the inner workings of the brain — and along the … -
April 18, 2022Ivan Iossifov, Michael Wigler and colleagues provided a detailed comparison of simplex and multiplex families with autism, supporting the view that de novo mutations are a more frequent …
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April 18, 2022CUNY’s Andrea Alù describes how metamaterials — materials engineered to have properties not found in nature — are paving the way for a wide range of technological advancements, from … -
April 14, 2022The partnership will support fellowships for threatened scholars in mathematics, computer science and theoretical physics. -
April 13, 2022On April 13, NASA has awarded Simons Foundation president David Spergel its Exceptional Public Service Medal, in a virtual ceremony telecast. The award cites Spergel’s “outstanding leadership … -
Funded WorkThe potential impact of maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the developing fetal brain is not yet understood. -
April 4, 2022Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond. -
Funded WorkOver the past few decades, there have been significant gains made in modern communication technology, yet there exists a huge gap in the application of these technologies to … -
Funded WorkAtypical brain activity and connectivity are well demonstrated in older children and adults with autism spectrum disorder (ASD), but it is unknown when these changes first appear. -
March 29, 2022Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
March 29, 2022The ability to record neural activity from populations of single cells in the human brain is expanding. What will these efforts reveal about neural dynamics? -
March 29, 2022In efforts to construct a map of neural connections in the brain, researchers at the Flatiron Institute’s Center for Computational Neuroscience are turning to an unlikely source … -
Funded WorkResearch on the functions of sleep has produced a wealth of evidence that sleep rhythms play an evolutionarily conserved role in the consolidation of multiple forms of memory. -
March 28, 2022Inflammation is a crucial part of our response to infection. Simons Junior Fellow Ashley Chui is working to uncover exactly how critical proteins in our cells support this … -
March 21, 2022… professorships, offer graduate student fellowships and run a summer school series for high school students aimed at introducing them to the field of computational physical chemistry. An … -
March 17, 2022By building a biophysical model that incorporates real-world biological complexity, scientists discover important links between the nanometer-sized motors that power a cell’s cilia and the … -
Funded WorkMutations in genes involved in synaptic function have been identified as risk factors for autism spectrum disorder (ASD), yet how risk-alleles encoding ubiquitous synaptic proteins affect the … -
Funded WorkAutism spectrum disorder (ASD) has a complex genetic landscape with many highly penetrant risk genes which individually affect a small proportion of individuals with a spectrum of clinical … -
Funded WorkThe massive outbreak of the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has spread rapidly around the … -
Funded WorkThe severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected hundreds of million individuals globally. -
Funded WorkAutism spectrum disorder (ASD) affects one in 59 children in the United States. -
Funded WorkPPP2R5D is a high-confidence (category 1) autism spectrum disorder (ASD) risk gene and the 13th most significantly neurodevelopmental disorder-associated gene in the genome. -
Funded WorkLoss-of-function mutations in repressive chromatin modifying enzymes such as euchromatic histone methyltransferase 1 (EHMT1) are frequent causes of neurodevelopmental conditions, including autism spectrum disorder (ASD). -
Funded WorkPost-transcriptional regulation of mRNAs plays a major role in determining the proteome and thus cell fate. -
Funded WorkAutism spectrum disorder (ASD) is a set of conditions arising during neural development. -
Funded WorkThere are currently no available evaluation tools specifically designed for online, rapid and repeated evaluation of multiple neurobehavioral domains important to people with autism spectrum disorder (ASD) and … -
Funded WorkThe objective of this one-year Director Award is to continue pathogenic copy number variation (CNV) discovery for exomes generated as part of the SPARK Consortium (the initial … -
March 14, 2022… group leaders, research scientists, postdoctoral fellows, computational engineers and support staff. Simoncelli sees the center as “living at the nexus” of three endeavors and communities: systems neuroscience … -
March 11, 2022The Simons Foundation is delighted to announce the 2022 class of Junior Fellows in the Simons Society of Fellows. These 12 researchers are outstanding early-career scientists and … -
Funded WorkFrom birth, infants and their caregivers engage in mutually adaptive and mutually reinforcing interactions that serve as the platform and catalyst for development of the social brain and … -
Funded WorkAutism spectrum disorder (ASD) is a complex, heritable and highly heterogeneous neurodevelopmental condition characterized by challenges in the core areas of reciprocal social communication as well as the … -
Funded WorkThe adaptive value of cognition manifests in decisions not only about how to act but also about when to act.
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March 8, 2022Now in its penultimate year, the Simons Collaboration on Quantum Fields, Gravity and Information has made a solid case for using quantum computing principles to understand spacetime, black … -
March 3, 2022Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.