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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. SFARI Sex Differences Collaboration Gather To Share Their Progress

    June 1, 2023
    On January 30–31, SFARI convened its first annual meeting of the SFARI Sex Differences Collaboration (SSDC). Funded in 2021, the SSDC collaboration consists of five groups of …
  2. Postponing the Launch of the Upcoming RFA on Genomics of ASD

    June 1, 2023
    Earlier this year we announced here that this summer we would be issuing a request for applications (RFA) for the Genomics of ASD grants. However, as we have …
  3. Simons Foundation Announces Historic $500 Million Gift to Stony Brook University Endowment

    June 1, 2023
    The Simons Foundation’s contribution is the largest unrestricted endowment gift to a higher education institution in American history.
  4. How Electrons and Nuclei Work Together To Build Our World

    May 30, 2023
    Simons Junior Fellow Eric Arsenault works at the intersection of physics and chemistry to understand how electrons and nuclei conspire — work that may lead to future energy and …
  5. Finding Order in the Chaos of the Cosmos

    May 23, 2023
    Flatiron Institute astrophysicist Adrian Price-Whelan studies the chaotic motions of stars in the Milky Way. His mission? To search for one of the universe’s best-kept …
  6. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    May 20, 2023
    Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.
  7. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    May 16, 2023
    Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
  8. Science Sandbox Hosts Second Annual Awardee Summit

    May 15, 2023
    More than 50 Science Sandbox grantees convened at the Simons Foundation for the two-day event.
  9. Science, Society and Culture at the Simons Foundation

    May 12, 2023
    … footprint, with a focus on areas of the country that have fewer traditional science engagement opportunities than cities like Boston or San Francisco. Our first initiative centers …
  10. First Class of Stony Brook Simons STEM Scholars Announced

    May 10, 2023
    … as mentors and role models. Cabrera was a Scholar in a similar program at the University of Maryland, Baltimore County, called the Meyerhoff Scholars Program. That program …
  11. 2023 Simons Investigators in Aquatic Microbial Ecology Announced

    May 9, 2023
    The Simons Foundation has named seven scientists as 2023 Simons Investigators in Aquatic Microbial Ecology. The five-year awards are intended to support outstanding recently tenured investigators in …
  12. The Ups and Downs of Modeling Oscillation

    May 9, 2023
    Flatiron Institute Research Fellow Fruzsina Agocs develops mathematical tools to help scientists understand oscillating systems — from the earliest moments of our universe to how sound bounces off complicated …
  13. Simons Foundation Renames Neuroscience Undergraduate Research Fellowship Program in Honor of Krishna Shenoy

    May 5, 2023
    … collaboration and mentorship of early-career researchers will live on in SURFiN, Picchini Schaffer says.
  14. Center for Computational Quantum Physics Announces New NYC Graduate Fellows

    May 1, 2023
    … made profound discoveries in superconductivity, statistical physics and nonlinear dynamics. The celebrated Hohenberg-Kohn theorem is foundational to CCQ’s work. The 2023 Pierre Hohenberg Fellow will …
  15. Ramamurti Shankar, Yale University, Joins the MPS Scientific Advisory Board

    April 28, 2023
    … Sciences and was a Visiting Professor at the Ecole Normale Superieure, Simons Professor KITP Santa Barbara , and Distinguished Visiting Professor the Indian Institute of Technology, Madras. He …
  16. Cutting-Edge Computational Study Provides ‘Gut Check’ to How We Thought Proteins Function

    April 28, 2023
    In using AI-powered tools to map proteins in the human gut microbiome, researchers have challenged the traditional view of the relationship between protein sequence, structure and function.
  17. 2023 Class of Junior Fellows Joins the Simons Society of Fellows

    April 27, 2023
    The Simons Foundation is pleased to announce the 2023 class of Junior Fellows in the Simons Society of Fellows. The 10 researchers are outstanding early-career scientists and …
  18. Looking for Patterns: Understanding How We See the World

    April 26, 2023
    At the Flatiron Institute, Tim Oleskiw combines experimental and computational methods to figure out how our visual systems work. He hopes his work can help spur advances in …
  19. Approaches for Measuring Sensory Function in ASD/NDD

    April 25, 2023
    On February 10, 2023, SFARI hosted an in-person meeting focused on measuring sensory system function in humans with autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDD).
  20. Stony Brook University Selected To Operate Center for Climate Solutions on New York’s Governors Island

    April 24, 2023
    … the social and practical challenges created by climate change — including research that becomes commercially viable and ideas that lead to immediate action on the local and global …
  21. Groundbreaking Experiment Rewinds Light Signals

    April 21, 2023
    Physicists have demonstrated a special type of reflection that could enable new forms of wireless communications and power-saving computers.
  22. Finding the Link Between Pain Sensitivity and Opioid Addiction

    April 20, 2023
    Behavioral neuroscientist and Simons Junior Fellow Andre B. Toussaint explores how pain sensitivity can exacerbate the risk of opioid addiction.
  23. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    April 12, 2023
    Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.
  24. Map of Space-Time Distortions Reveals Universe’s Dark Matter Distribution, Proving Einstein Right

    April 11, 2023
    A new analysis of measurements of the universe’s oldest light made by the Atacama Cosmology Telescope shows how ordinary and dark matter is spread across the cosmos …
  25. Going With the Flow: Mapping Vascular Systems in Fruit Flies

    April 3, 2023
    In her studies of insects, Flatiron Institute Research Fellow Tatyana Gavrilchenko is gaining new insights into the complexities of the vasculature system — work that could inform efforts at …
  26. MPS Announces New Scientific Advisory Board Members

    March 31, 2023
    … at Syracuse University in 2000, and was promoted to Professor, holding the Alumni Chair, in 2007, before moving to Penn in 2009. He has held visiting positions …
  27. From the bioRxiv: A Selection of Recently Posted Papers From SCPAB Investigators and Others

    March 31, 2023
    Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.
  28. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    March 28, 2023
    Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
  29. A Scientist’s Quest for Better Brain-Computer Interfaces Opens a Window on Neural Dynamics

    March 28, 2023
    Krishna Shenoy set out to develop workable prosthetics for profoundly paralyzed people. Along the way, he helped usher in a novel framework for deciphering neural activity.
  30. Finding Order in Apparent Randomness

    March 27, 2023
    Simons Junior Fellow Morris Ang develops and proves theorems that help explain the hidden mathematical patterns in random surfaces or objects.
  31. Excessive Protein Degradation Is Identified as a New Cellular Pathology and a Potential Target for Therapeutic Intervention in Fragile X Syndrome

    March 23, 2023
    In a mouse model of fragile X syndrome, Emily Osterweil and her colleagues show that excessive protein synthesis drives a pathological compensatory rise in protein degradation (by the …
  32. 2022 Genomics of ASD: Pathways to Genetic Therapies Awardees Announced

    March 23, 2023
    SFARI is pleased to announce that it intends to fund 15 grants in response to the 2022 Genomics of ASD: Pathways to Genetic Therapies request for applications.
  33. Simons Foundation Accepting Applications for Neuroscience Undergraduate Research Fellowships

    March 23, 2023
    The Simons Foundation is now accepting applications from undergraduate students to participate in the Simons Foundation Undergraduate Research Fellowship in Neuroscience, or SURFiN, for the 2023–2024 academic …
  34. Artificial Intelligence Discovers Secret Equation for ‘Weighing’ Galaxy Clusters

    March 23, 2023
    … equations can help us in maximizing the scientific return from these surveys.” Wadekar also hopes that this publication will be just the tip of the iceberg when …
  35. Advancing Astronomy With Statistics

    March 20, 2023
    By marrying statistical techniques with computational tools, Flatiron Institute research scientist Dan Foreman-Mackey is helping astronomers probe the atmospheres of other planets.
  36. A Novel Eye-Tracking Paradigm Identifies an Influence of Perceptual Load on Social Attention in Autism

    March 14, 2023
    A study by Caroline Robertson and her colleagues found that reduced social attention was not a static omnipresent characteristic of autism; rather, it was magnified only under certain …
  37. Why Don’t Disease-Linked Genetic Mutations Always Result in Disease? A Study in Fruit Flies Offers New Clues

    March 13, 2023
    By harnessing both experimental and computational methods, researchers have identified a significant role for randomness in disease manifestation.
  38. Computational Model Uncovers New Insights Into How Our Brains Store Information

    March 9, 2023
    With the new model, researchers reveal how memories and learned behaviors can remain strong, even in the face of shifting neural representations.
  39. Watch: How Emily Rauscher Maps an Exoplanet’s Atmosphere

    March 8, 2023
    An astronomer at the University of Michigan and a 2022 Simons Fellow in Theoretical Physics, Emily Rauscher works to characterize the atmospheric properties of distant worlds.
  40. Stepping in the Right Direction: Optimizing Machine Learning

    March 7, 2023
    Flatiron Institute mathematician Neha Wadia is developing a new set of learning algorithms to improve machine learning optimization.
  41. A New Approach To Analyzing Genomic Association Data Finds Convergence of Both Rare and Common Genetic Influences on Autism at Chromosome 16p

    March 6, 2023
    Elise Robinson and colleagues identified a large genomic region — chromosome 16p — where a rare 16p11.2 variant associated with autism functionally converges with common polygenic variation across 16p …
  42. 2023 Simons Fellows in Mathematics Announced

    March 6, 2023
    The Simons Foundation congratulates the outstanding mathematicians who have been awarded Simons Fellowships in 2023. The Simons Fellows program extends academic leaves from one term to a full …
  43. Simons Foundation Now Accepting Applications for Second Class of Pivot Fellows

    March 1, 2023
    The Simons Foundation is now accepting applications for its second class of Pivot Fellowships. The program provides funding for today’s brightest minds to apply their talent and …
  44. New Testing Approach Diagnoses COVID-19 With Near-Perfect Accuracy

    February 27, 2023
    By monitoring the body’s molecular response to a viral attack, the new method developed by Flatiron Institute researchers and their colleagues can diagnose even asymptomatic patients with …
  45. Exploring the Role of Dopamine in Natural Behaviors

    February 27, 2023
    New research suggests that the neuromodulator plays a role in learning even in the absence of external rewards. The work also raises new questions.
  46. What Really Happens When Stars Form?

    February 27, 2023
    Guided by his longtime fascination with the cosmos, Simons Junior Fellow Lachlan Lancaster is challenging established views of how stars are born.
  47. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    February 24, 2023
    Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
  48. Conference Spotlight: Cosyne 2023

    February 23, 2023
    Check out these talks and workshops featuring Simons Collaboration on the Global Brain investigators and fellows.
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