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July 29, 2021The Simons Collaboration on the Global Brain (SCGB) is pleased to announce its inaugural class of Bridge to Independence (BTI) fellows. -
July 28, 2021… of being internally quantitative, meaning that you can count the absolute number of molecules that were in the starting material. That’s probably the next 20 years … -
July 28, 2021With new tools offering an unprecedented view of a planet’s molecular building blocks, astrochemists are working to pin down the recipe for a habitable world. -
July 27, 2021Galaxy clusters are some of the largest known structures in the universe. Astrophysicist Chris Hayward explains what happens when galaxies within those clusters collide. -
July 27, 2021Magnetic fields around black holes decay quickly, report researchers from the Flatiron Institute, Columbia University and Princeton University. This finding backs up the so-called ‘no-hair conjecture … -
July 26, 2021Across animal species and human cultures, females outlive males and appear less susceptible to cognitive decline with age. Scientists are exploring these sex-linked differences to identify interventions … -
July 26, 2021New study in Nature Genetics uses SPARK database to investigate variants that are less damaging than de novo mutations, but contribute almost as much risk. -
July 26, 2021Simons Junior Fellow Jarosław “Jarek” Błasiok, a theoretical computer scientist, seeks to make computers more efficient and accurate — even in the face of increasingly large datasets. -
July 21, 2021… harness this property, including in computers,” Rao says. -
July 21, 2021Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond. -
July 21, 2021Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
July 20, 2021Vikaas Sohal and John Rubenstein found that Pogz heterozygous mice exhibited reduced anxiety-related avoidance behavior and that this correlated with impaired communication between the ventral hippocampus and …
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July 20, 2021Three SFARI Investigators and the deputy director of Clinical Research Associates, LLC (an affiliate of the Simons Foundation) were recently appointed to serve on the Interagency Autism Coordinating … -
July 19, 2021Vanessa Troiani and colleagues demonstrated a linear relationship between pupil dilation, reward/punishment sensitivity and individual ASD diagnostic status. -
July 19, 2021Flexible electrodes offer an alternative approach to silicon probes for high-density recordings. Both methods face challenges in how to best process data. -
July 19, 2021Novel technologies to simultaneously record from hundreds to thousands of neurons over weeks and months grant access to the brain at an unprecedented resolution. Researchers are now tackling … -
July 19, 2021Robi Mitra and colleagues have developed a scalable CRISPR/Cas9 RNA sequencing assay in a human neuronal differentiation cell model, enabling high-throughput assessments of how repression of …
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Funded WorkTRIO is among the genes most frequently impacted by damaging de novo mutations and rare variants in individuals with autism spectrum disorder (ASD), severe intellectual disability (ID), schizophrenia … -
Funded WorkSince the fall of 2008, Abba Krieger and colleagues (most prominently Andreas Buja) at the Wharton School of the University of Pennsylvania have served as statistical consultants to … -
July 12, 2021… health volunteer in what is now the Democratic Republic of the Congo, and as editor and researcher for the Journal of Public Health in Africa. Her experiences … -
July 9, 2021Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
July 7, 2021The CAMELS project is the largest set of detailed cosmological simulations designed to train machine-learning algorithms. -
Funded WorkThe integrated stress response (ISR) has recently emerged as a main causative driver of normal aging as well as a wide spectrum of cognitive disorders of vastly different … -
Funded WorkDespite the increase in the prevalence of autism spectrum disorder (ASD), currently, there are no treatments that can effectively reverse ASD core features. -
July 6, 2021… Pasadena, California, before joining the University of Washington faculty in 1998. Dalcanton has received numerous recognitions for her work, including an Alfred P. Sloan Research Fellowship, a … -
July 1, 2021… to have significant impacts,” he says. “In the long run, it will be the combination of the scientists we train and the transformative results we enable that … -
June 29, 2021… says Edholm. “How do people get infected and how do people get recovered? And how do you move through these infections and how do they propagate?” Getting … -
June 29, 2021… “Goodbye” but like a “See you soon.” We will remain close by and will eagerly follow this new stage of the Simons Foundation, led by David Spergel … -
June 28, 2021On April 26 and 29, 2021, SFARI and the Simons Initiative for the Developing Brain hosted a virtual workshop that focused on the use of rats as a … -
June 28, 2021Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond. -
June 28, 2021Epigenetic clocks capture aging processes at the molecular level. Now, researchers grapple with how they work and what they mean. -
June 28, 2021Molecular biologist and Simons Junior Fellow Naama Aviram works to understand how individual cells function — a more mysterious process than often appreciated. Beyond the sheer lure of scientific … -
June 24, 2021… neural-net likelihood, simulation-based or likelihood-free inference techniques that have the potential to fully exploit the enormous amount of information from upcoming observational surveys. By … -
June 24, 2021The Simons Foundation is pleased to announce the establishment of the Simons Collaboration on Global Categorical Symmetries, directed by Constantin Teleman of the University of California, Berkeley. This … -
June 22, 2021In conjunction with leading universities across the county, SFARI works to provide undergraduates with an opportunity to advance their careers in autism science while promoting diversity in the … -
June 22, 2021The Simons Foundation is pleased to announce that mathematical physicist Robbert Dijkgraaf has joined its board of directors. Dijkgraaf is director of and Leon Levy Professor at the … -
June 10, 2021The 33rd Annual Workshop on Recent Developments in Electronic Structure Methods (ES21) will be hosted online by the Center for Computational Quantum Physics (CCQ), Flatiron Institute, July 12 … -
June 10, 2021Known for his extraordinary ability to bridge disparate fields, mathematician Andrei Okounkov finds connections everywhere he goes. -
June 9, 2021SFARI announces the recipients of the Autism BrainNet Appreciation Award, a new honor that recognizes outstanding partners and collaborators for their dedication to advancing brain tissue research in … -
June 7, 2021Ten years after its launch, Simons Searchlight counts a community of 4,000 families, encompassing more than 150 genetic neurodevelopmental conditions. Thanks to the dedicated, highly motivated families … -
June 3, 2021Despite renewed attention, definitive conclusions remain elusive for a decades old theory of how the visual system may work in reverse. -
Funded WorkAccumulating evidence indicates that autism spectrum disorder (ASD) susceptibility mutations are frequently found within genes encoding chromatin regulators that control the expression of genes across the genome. -
May 26, 2021The International Society for Autism Research (INSAR) Virtual 2021 Annual Meeting was held May 3–7, 2021. A selection of presentations by SFARI Investigators, SFARI staff and collaborators … -
May 25, 2021… medical and technological breakthroughs now central to the world’s pandemic response. With support from the Kavli Foundation and the Simons Foundation, the Science Philanthropy Alliance has … -
May 25, 2021Simons Junior Fellow Michael Waskom studies what happens in the brain when we need to decide something quickly, like whether to cross the street against a red light … -
May 24, 2021Elizabeth Jonas and colleagues identified a molecular mechanism underlying the contributions of mitochondrial dysfunction to the synaptic and behavioral features associated with fragile X syndrome. -
May 24, 2021Hirofumi Morishita and colleagues showed that juvenile social isolation leads to deficits in adult mouse sociability via reduced activation of a prefrontal-paraventricular thalamus circuit. -
May 24, 2021Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.