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  • Bringing people and ideas together to fund, conduct, and share transformative science.

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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

  • All News
  • Research News
  • Funding Announcements
  • Newsletter Sign Up
  • Press Releases
  • Media Relations

We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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  • Public Events
  • Presidential Lectures
  • Presents
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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  • Simons Collaboration on Localization of Waves
  • Simons Collaboration on Plasticity and the Aging Brain
  • Simons Collaboration on Principles of Microbial Ecosystems
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Science, Society & Culture
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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Developmental Dynamics Group Meeting

    Meeting
  2. CCB Brown Bag Seminar

    Seminar
  3. Genomics Group Meeting

    Meeting
  4. Developmental Dynamics Group Meeting

    Meeting
  5. Genomics Group Meeting

    Meeting
  6. CCB Seminar: Bo Li, Ph.D. (University of California, San Diego)

    Seminar
    Speaker: Bo Li, Ph.D., Department of Mathematics, University of California, San Diego Speaker: Bo Li, Ph.D., Department of Mathematics, University of California, San Diego Title: Computational …
  7. Developmental Dynamics Group Meeting

    Meeting
  8. CCB Brown Bag Seminar

    Seminar
  9. Biomolecular Design Group Meeting

    Meeting
  10. Active Matter Journal Club

    In Conversation
  11. Genomics Group Meeting

    Meeting
  12. Developmental Dynamics Group Meeting

    Meeting
  13. CCB Coffee Hour

    Event
  14. EMIG Seminar: Valentin Peretroukhin, Ph.D. (Structura Biotechnology)

    Seminar
    Speaker: Valentin Peretroukhin, Ph.D., Computational Research Scientist at Structura Biotechnology Title: A matter of perspective: diagnosing and dealing with preferred orientation in cryo-EM Preferred orientation, the …
  15. Active Matter Journal Club

    In Conversation
  16. Biomolecular Design Group Meeting

    Meeting
  17. Inference of Dynamic Networks in Biological Systems

    Seminar
    Abstract Biological systems are complex dynamic networks. In this talk, I will introduce GOBI (General Model-based Inference), a simple and scalable method for inferring regulatory networks from …
  18. CCB Seminar: Jae Kyoung Kim, Ph.D. (KAIST)

    Seminar
    Speaker: Jae Kyong Kim, Associate Professor, Department of Mathematics, KAIST
  19. CCB Colloquium: Leonid Mirny, Ph.D. (Massachusetts Institute of Technology)

    Colloquium
    Speaker: Leonid Mirny Professor in Medicine and Biomedical Physics, and Physics, Massachusetts Institute of Technology
  20. Active Matter Journal Club

    In Conversation
  21. CCB Seminar: Decoding Cellular Identities from Single-Cell Data

    Seminar
    Speaker: Zoe Piran, The Hebrew University of Jerusalem Title: Decoding cellular identities from single-cell data Molecular profiling of a cell captures multiple overlapping signals arising from its …
  22. CCB Brown Bag Seminar

    Seminar
    Speaker:  Hayden Nunley, Flatiron Research Fellow, Developmental Dynamics Title: Quantifying and modeling the growth of lineage trees To transform a fertilized egg into a complex multicellular organism, mitotic …
  23. CCB Seminar: A Computational Perspective on the Metastable Phase Behavior of Water (Pablo Debenedetti, Ph.D.)

    Seminar
    Speaker:  Pablo Debenedetti, Ph.D., Princeton University Topic: A computational perspective on the metastable phase behavior of water The preponderance of experimental evidence is consistent with the existence …
  24. Genomics Group Meeting

    Meeting
  25. Structural & Molecular Biophysics Group Meeting

    Meeting
  26. Genomics Group Meeting

    Meeting
  27. Genomics Group Meeting

    Meeting
  28. Structural & Molecular Biophysics Group Meeting

    Meeting
  29. CCB Brown Bag Seminar

    Seminar
  30. Structural & Molecular Biophysics Group Meeting

    Meeting
  31. Genomics Group Meeting

    Meeting
  32. Biophysical Modeling Group Meeting

    Meeting
  33. CCB Colloquium: Jian Zhou, Ph.D., UT Southwestern Medical Center

    Colloquium
  34. Biophysical Modeling Group Meeting

    Meeting
  35. Genomics Group Meeting

    Meeting
  36. Structural & Molecular Biophysics Group Meeting

    Meeting
  37. Biophysical Modeling Group Meeting

    Meeting
  38. Biophysical Modeling Group Meeting

    Meeting
  39. Genomics Group Meeting

    Meeting
  40. Biophysical Modeling Group Meeting

    Meeting
  41. Structural and Molecular Biophysics Group Meeting

    Meeting
  42. Genomics Group Meeting

    Meeting
  43. Developmental Dynamics Group Meeting

    Meeting
  44. Mechanics of Life II: Models and Methods

    Workshop
    From the active metropolis inside each living cell to the vibrant dynamics of motile microorganisms, mechanical insights continue to advance our understanding of the living world. Hosted by …
  45. Genomics Group Meeting

    Meeting
  46. Structural and Molecular Biophysics Group Meeting

    Meeting
  47. Biophysical Modeling Group Meeting

    Meeting
  48. Developmental Dynamics Group Meeting

    Meeting
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