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October 14, 2014SFARI held its sixth annual meeting, bringing together some 150 SFARI-supported autism researchers in an effort to advance the understanding of autism, improve its diagnosis and better … -
August 27, 2014The meeting brought together families with a child carrying deletions or duplications in chromosomal region 16p11.2 and researchers studying 16p11.2. -
August 12, 2014On 2 September, we plan to announce a new request for applications. Letters of intent, the short statements that precede full applications, are due no later than 10 … -
July 15, 2014On 12 and 13 June, the Simons Foundation Autism Research Initiative (SFARI) held its second workshop on 16p11.2 deletion and duplication. A total of 62 participants from … -
July 3, 2014Mouse models provide an essential platform for studying the neural circuits underlying autism spectrum disorders. -
May 27, 2014New collaboration will collect critically needed brain tissue for autism research -
May 1, 2014SFARI’s chief scientist, Gerald Fischbach, provides an overview of what we know and what we need to learn about autism and related developmental disorders. We hope this … -
April 25, 2014SFARI director of clinical research Wendy Chung presented What We Know About Autism to those gathered in Vancouver, Canada, for the TED2014 conference on March 19, 2014. The … -
September 3, 2013Today, we’re announcing a new request for applications. Letters of intent, the short statements that precede full applications, are due no later than 11 October. It seems … -
May 16, 2013The Simons Foundation is pleased to announce that Louis F. Reichardt of the University of California, San Francisco (UCSF) will become the next director of the Simons Foundation … -
April 9, 2013For individuals with autism, a trip to the clinic — an unfamiliar place with strange people and instruments — can be exceedingly stressful. And as many genetic databases for autism … -
March 12, 2013A number of autism risk factors converge on one cellular pathway: abnormal remodeling of the cell’s structural systems through the signaling protein Rho, says SFARI’s associate … -
February 12, 2013Glia were once thought to play a secondary role to neurons in the brain. But studies in the past few years have shown that they may be involved … -
November 6, 2012Converging lines of evidence suggest that the earliest events in brain development play a role in autism. On 12 September, the Simons Foundation Autism Research Initiative brought together … -
October 30, 2012Which grant applications should SFARI choose to fund each year? The principles that guide that decision are nuanced and evolve as new results emerge. But there are some … -
September 25, 2012New genetic variants that increase susceptibility to autism are emerging at a rapid pace. Given the profusion of data, it seems timely to assess the availability and usefulness … -
August 7, 2012The chromosomal region 16p11.2, which spans about 29 genes, is strongly linked to autism. On 27 April, SFARI hosted a workshop to discuss the consequences of duplications …
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April 17, 2012Studies suggest that a subset of children with autism make significant social and language gains in the first year of life, and then experience a dramatic loss of … -
March 13, 2012Dysregulation of the intracellular signaling pathway RAS, a risk factor for idiopathic autism, may provide a unifying theory of the disorder. Although this is not an altogether new … -
December 14, 2011More than 100 investigators and clinicians who worked together on the Simons Simplex Collection gathered in New York City to celebrate their landmark achievement in autism research. -
October 4, 2011Researchers can use biomarkers to diagnose individuals with autism and to hone in on the underlying causes of the disorder. In July, SFARI held an informal meeting of … -
August 22, 2011SFARI scientific director Gerald Fischbach and principal investigator Catherine Lord of the University of Michigan published The Simons Simplex Collection: A Resource for Identification of Autism Genetic Risk … -
August 19, 2011In a milestone for the autism research community, SFARI has finished recruiting families to participate in the Simons Simplex Collection (SSC). The foundation has now shifted from recruitment … -
May 19, 2011Preliminary studies suggest that the so-called ‘love hormone’ oxytocin could improve some of the social deficits characteristic of people with autism. On 11 April, SFARI hosted a … -
May 3, 2011Children with autism often have behaviors that suggest problems with attention. It is unclear whether this attention deficit causes the other symptoms of autism or is a consequence … -
April 14, 2011SFARI is pleased to announce the SFARI Explorer Awards program: an initiative designed to provide timely support to innovative, high-risk experiments relevant to our mission. -
April 11, 2011In November, the Simons Foundation Autism Research Initiative (SFARI) launched a request for applications, calling for letters of intent from individuals who will conduct bold, imaginative and rigorous … -
March 23, 2011Researchers need reliable methods to interpret autism candidate genes, including rodent models to assess the impact of genes on behavior. On 4 February, SFARI hosted a workshop to … -
February 1, 2011A study on a SHANK3 mutation highlights the danger in using research tools to inform decision-making in the doctor’s office. This sort of concern is one … -
September 29, 2010Several studies have shown that a micro-duplication within 15q11-13 — a region on chromosome 15 — on the maternal chromosome is associated with autism. The duplicated region contains … -
June 22, 2010Much of the recent advances in autism have been on the genetic and behavioral levels of dysfunction present in the disorder. Comparatively little is known about altered function … -
April 1, 2010On 5 February 2010, the Simons Foundation gathered a panel of experts to discuss what initially appears to be a surprising and unrelated pair of subjects: autism and … -
March 25, 2010Sharmila Banerjee-Basu, founder and president of Mindspec Inc., and Alan Packer, associate director for research at SFARI, have published an article describing a new SFARI Gene module … -
January 22, 2010As the number of available DNA samples continues to increase and the cost of sequencing continues to drop, one can’t help but want to capture all of … -
January 11, 2010Fever has benefits beyond its role in fighting infection. According to a prospective study published in 2007 and to many anecdotal reports, fever can improve cognitive function and … -
October 8, 2009Autism research has attracted a remarkable diversity of scholars. Many of them have developed an understanding of concepts in fields that are not their own, but it is … -
February 24, 2009The SFARI team is pleased to announce the launch of SFARI Gene, a new online tool for autism researchers. -
October 1, 2008Autism is a developmental disorder characterized by impaired social interaction and communication, and restricted and repetitive behavior. Because there are no biological markers for the disorder, it is …