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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. XMC Workshop

    Workshop
    … globular clusters SOC: Danny Horta, David Nidever, Adrian Price-Whelan, Mary Putman, Nitya Kallivayalil, Kate Daniel, and Nico Garavito-Camargo LOC: Danny Horta and Nico Garavito-Camargo
  2. 2024 Simons Collaboration on Extreme Electrodynamics of Compact Sources Annual Meeting

    Conference
    … self-consistent calculations infeasible and introduces great challenges for modeling magnetospheric processes. Some key questions addressed by SCEECS are: What is the origin of the radio-loud …
  3. Engineering Life One Molecule at a Time

    Lecture
    Biological matter is the only matter that ostensibly exists for a purpose — life. However, how can the laws of physics define life? Living systems operate far from thermodynamic …
  4. XMC Workshop

    Workshop
    … globular clusters SOC: Danny Horta, David Nidever, Adrian Price-Whelan, Mary Putman, Nitya Kallivayalil, Kate Daniel, and Nico Garavito-Camargo LOC: Danny Horta and Nico Garavito-Camargo
  5. QUAST Conference

    Conference
    … (University of Hamburg) Two-particle self-consistency in diagrammatic extensions of the dynamical mean field theory 12:15- 1:45 PM (1.5hr) Lunch
  6. Structural & Molecular Biophysics Group Meeting

    Meeting
  7. Genomics Group Meeting

    Meeting
  8. Biophysical Modeling Group Meeting

    Meeting
  9. XMC Workshop

    Workshop
    … globular clusters SOC: Danny Horta, David Nidever, Adrian Price-Whelan, Mary Putman, Nitya Kallivayalil, Kate Daniel, and Nico Garavito-Camargo LOC: Danny Horta and Nico Garavito-Camargo
  10. Developmental Dynamics Group Meeting

    Meeting
  11. XMC Workshop (SDSS-V)

    Event
  12. XMC Workshop

    Workshop
    … globular clusters SOC: Danny Horta, David Nidever, Adrian Price-Whelan, Mary Putman, Nitya Kallivayalil, Kate Daniel, and Nico Garavito-Camargo LOC: Danny Horta and Nico Garavito-Camargo …
  13. Sharp Shots and Hot Hands

    In Conversation
    … a brain-machine interface model to probe how dopamine orchestrates the sculpting of neural circuits during reinforcement learning. Tim Chartier is an applied mathematician with a focus …
  14. CCA Colloquium: Kishalay De (Job Talk)

    Colloquium
    Title: Uncovering dust enshrouded cataclysms toward a census of stellar and black hole evolution Abstract: Multiplicity is ubiquitous in stars and the remnants they leave behind. While eruptive …
  15. Online Community Meeting for Calcium and Voltage Imaging Analysis

    Event
    The next open Community Meeting for Calcium and Voltage Imaging Analysis using Caiman, Fastplotlib, and Mesmerize.  Come and chat with developers and users about where things are, and …
  16. CCB Brown Bag Seminar

    Seminar
    Speaker:  Hayden Nunley, Flatiron Research Fellow, Developmental Dynamics Title: Quantifying and modeling the growth of lineage trees To transform a fertilized egg into a complex multicellular organism, mitotic …
  17. Nonlinear Spectroscopy Workshop

    Workshop
    … (University of Chicago) Controlled approaches to nonlinear response from effective field theory 12:30 – 2:00 PM Lunch 2:00 – 2:45 PM Mark Sherwin (UC Santa …
  18. AI in Climate Science: From Emulation to New Discoveries

    Lecture
    Simulating Earth’s climate is a tough task, involving representing many complex processes such as turbulence, convection and terrestrial processes such as phenology. Recently, AI has proven to …
  19. MPS Conference on Quantitative Topology and Related Areas

    Conference
    … scalar curvature for polyhedra. This is joint work with Jinmin Wang and Zhizhang Xie. February 21, 2024 Mikolaj Fraczyk | Minimal Submanifolds in Locally Symmetric Spaces February 21 …
  20. Machine Learning at the Flatiron Institute Seminar: Tim Rudner

    Seminar
    Title: Data-Driven Priors for Trustworthy Machine Learning Abstract: Machine learning models, while effective in controlled environments, can fail catastrophically when exposed to unexpected conditions upon deployment. This …
  21. Structural & Molecular Biophysics Group Meeting

    Meeting
  22. Biophysical Modeling Group Meeting

    Meeting
  23. Inaugural Workshop of the Initiative for Computational Catalysis

    Workshop
    … February 19, 2024 Ismaila Dabo: Computational modeling of (photo) electrocatalytic materials and interfaces February 19, 2024 Andrew Rosen: Heterogeneous Catalysts with Unique Electronic Structure Properties Identified from …
  24. CCA Colloquium: Maya Fischbach

    Colloquium
    Title: TBD Abstract: TBD CCA Colloquium stake place on select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the …
  25. CCB Seminar: A Computational Perspective on the Metastable Phase Behavior of Water (Pablo Debenedetti, Ph.D.)

    Seminar
    Speaker:  Pablo Debenedetti, Ph.D., Princeton University Topic: A computational perspective on the metastable phase behavior of water The preponderance of experimental evidence is consistent with the existence …
  26. Flatiron Institute Seminar Series: Dmitri Chklovskii

    Seminar
    Title: Reimagining the Neuron as a Controller Abstract: Modern Artificial Intelligence (AI) systems, such as ChatGPT, rely on artificial neural networks (ANNs), which are historically inspired by the …
  27. CCB Seminar: Protein Structural Ensembles from 3D and 2D Cryo-EM Data (Massimiliano Bonomi, Ph.D.)

    Seminar
    … F. E. Thomasen, K. Lindorff-Larsen, M. Bonomi. bioRxiv (2023) 2023.10.18.562710
  28. Genomics Group Meeting

    Meeting
  29. 2024 Simons Collaboration on Localization of Waves Annual Meeting

    Conference
    … the magnetic Schrödinger operator that is designed to highlight only strong candidates for eigenpairs satisfying the given criteria. Heuristic, theoretical and computational support will be provided for …
  30. Neurobiology for Social Touch, From Mice to Naked Mole Rats

    Lecture
    Our skin isn’t just a protective covering; it’s a way to sense the world around us. Our brains and skin are closely connected and constantly communicate …
  31. Accelerating Discovery in Climate Physics with Machine Learning

    Lecture
    The oceans are a crucial component of the climate system. They store and redistribute most of the excess heat from anthropogenic emissions. Climate simulations have been essential for …
  32. Genomics Group Meeting

    Meeting
  33. Machine Learning at the Flatiron Institute Seminar: Alex Wiltschko

    Seminar
    Title: Mapping scent Abstract: We’ll go through three sets of results showing that a) olfaction is a sense that can be mapped, albeit only in high-dimensions …
  34. DMFT-QE Symposium: February 5, 2024

    Symposia
    … 2, 024307 (2021) [2] Z. Zhong et al, Phys. Rev. Lett. 114, 246401 (2015) [3] M. Pickem, JMT, K. Held, Phys. Rev. Research 4, 033253 (2022) [4 …
  35. CCA Colloquium: Jessie Christiansen

    Colloquium
    Title: From Kepler to the Habitable Worlds Observatory: The Emerging Picture of Planet Populations Abstract: The NASA Kepler mission has provided its final planet candidate catalogue, the K2 …
  36. CCA Colloquium Schedule

    Colloquium
    Select Fridays From 3:00pm to 4:00pm in the 5th floor classroom, followed by a reception outside the 5th-floor conference room from 4:00pm – 5:30pm
  37. 2024 Simons Collaboration on the Theory of Algorithmic Fairness Annual Meeting

    Conference
    … Parikshit Gopalan | Omniprediction and Multigroup Fairness February 1, 2024 Aaron Roth | What Should We Trust in “Trustworthy ML”? February 1, 2024 Toni Pitassi | Replicability February 1, 2024 …
  38. Understanding How Biological Cells Self-Organize Into Organs and Organisms

    Lecture
    In multicellular organisms, properly programmed collective motion is required to form tissues and organs. Such programming breaks down in diseases like cancer. Recent experimental work highlights that some …
  39. Structural & Molecular Biophysics Group Meeting

    Meeting
  40. Genomics Group Meeting

    Meeting
  41. Quantum Cafe: Riccardo Comin

    Colloquium
    … energy [4]. January 30, 2024 Riccardo Comin: Flat Bands and Correlation Physics
  42. CCA Colloquium: P. Chris Fragile

    Colloquium
    Title: The Luminous, Hard State Can’t Be MAD Abstract: I will present a straightforward argument for why the luminous, hard state of black hole X-ray binaries …
  43. How Exoplanets Provide Insight Into Atmospheric Physics Within Extreme Regimes

    Lecture
    … Simons Fellow in Theoretical Physics.
  44. Genomics Group Meeting

    Meeting
  45. Machine Learning at the Flatiron Institute Seminar: Francesca Mignacco

    Seminar
    Title: Statistical physics insights into the dynamics of learning algorithms Abstract: In this talk, I will consider prototypical learning problems that are amenable to an exact characterization. I …
  46. Structural & Molecular Biophysics Group Meeting

    Meeting
  47. To the Stars and Back

    In Conversation
    … black hole.
  48. 2024 CCA Pre-Doc Symposium

    Symposia
    The Pre-Doc symposium will showcase the work of our Fall 2023 Pre-Doc class. Join us from 2:00pm to 4:20pm in the Ingrid Daubechies Auditorium …
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