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Mark Daly and colleagues report the results of a large genome-wide association meta-analysis of more than 18,000 individuals with ASD, including the newly genotyped Danish … -
Artificial networks trained to perform a variety of tasks develop functional clusters of cells that can be recruited to different tasks. The findings may help scientists understand the … -
… State University Denis Osin Vanderbilt University Dmitry Panchenko University of Toronto Irena Peeva Cornell University Malabika Pramanik University of British Columbia Eric Rowell Texas A&M University … -
Family-organized groups are planning a number of meetings in 2019 for individuals with rare genetic neurodevelopmental conditions, including those due to 16p11.2 copy number variants and … -
How do neural circuits hold on to an idea even though individual neurons only fire within milliseconds after stimulation? So-called attractor dynamics may explain memory-related activity. -
Eva Silverstein of Stanford University connects the mathematical structure of string theory to predictions for cosmological observables. -
The FASER detector will seek clues pointing to hidden matter in the universe. -
The tool, called CaImAn, replaces the process of manually tracking the location and activity of neurons. -
SFARI Viewer, an online platform to visualize and analyze SFARI genomic data, was recently launched. This tool was developed through a collaboration between the SFARI Informatics team, Frameshift … -
Genetically altered gut bacteria could produce compounds that fight cancer, depression and other ailments. Synthetic biologist Carlotta Ronda of the Simons Society of Fellows investigates how bacteria could … -
First-of-its-kind study could aid research into how our sense of smell is affected by the decreasing number of neurons in our noses as we age. -
Meta–Analysis of De Novo Mutations Yields Longer List of Risk Genes for Neurodevelopmental Disorders
Evan Eichler and colleagues performed a meta-analysis of de novo mutations from individuals with ASD, intellectual disability or developmental delay and found new risk genes for neurodevelopmental … -
Stephan Sanders and colleagues used a machine learning approach to analyze whole-genome sequencing data from more than 1,900 SSC families and found that de novo noncoding … -
Dan Feldman and colleagues analyzed four mouse models of autism and found that alterations in the excitation-inhibition ratio may serve as a homeostatic mechanism to prevent network … -
SFARI is pleased to announce that it intends to fund 15 grants in response to the Winter 2019 Pilot Award request for applications (RFA). -
Check out these talks and workshops featuring investigators from the Simons Collaboration on the Global Brain. -
New data were recently added to SFARI Gene. This data release included updated gene scores for candidate autism risk genes, as well as the addition of new genes … -
… the same values, which means our standard cosmological model might be flawed.” Feeney, Peiris and colleagues developed a universally applicable technique that calculates how gravitational wave data … -
Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond. -
Paul J. Steinhardt, a key developer of cosmic inflation in the big bang theory, has second thoughts about that model. Instead, he is revisiting the idea of a … -
Neurons in the visual cortex that project to different downstream areas tend not to be connected to each other even though they are functionally similar. -
New simulations reveal how interactions between magnetic fields and particles sap a black hole’s energy. -
SCGB director David Tank discusses how virtual reality and two-photon imaging can probe the role of neural sequences in cognition. -
Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
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A device built from readily available components can image multiple brain areas during a decision-making task. -
The neurotransmitter famously provides the thrill we get from a surprise, a phenomenon known as reward prediction error. But growing evidence suggests the chemical also tracks movement, novelty … -
This year’s award honors Sallie W. Chisholm for her research on Prochlorococcus, the most abundant photosynthetic cell in the seas -
Autism BrainNet is now distributing frozen and fixed postmortem brain tissue from individuals with autism spectrum and other neurodevelopmental disorders, as well as neurotypical individuals, for use in … -
An initiative of the California Academy of Sciences, this citizen-science-driven, national program allows kids and adults to experience nature in their communities in new ways. -
Two completely disparate fields will show the same type of mathematical structure, hinting at a connection. Yi Sun of the Simons Society of Fellows uses representation theory to … -
The prize recognizes outstanding research by a postdoctoral female astronomer. -
Most familiar in displays, liquid crystals behave in unusual ways that could lead to new developments in science and technology, points out Lisa Tran, a chemical engineer and … -
As part of the Imagine Science Film Festival, the Symbiosis Competition pairs a scientist with a filmmaker and challenges them to work together. -
A new, improved version of SFARI Base that streamlines and facilitates the process whereby researchers can request access to SFARI data and biospecimens as well as the submission … -
On February 22, 2018, SFARI organized a workshop on the uses of digital tools for phenotyping cognition and behavior in brain disorders. Goals of the workshop included learning … -
New data were added to SFARI Gene in November 2018. This data release included updated gene scores for candidate autism risk genes, as well as the addition of …
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SFARI is pleased to announce that it has selected four awardees in response to the 2018 Bridge to Independence Award request for applications. This program helps early-career … -
Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
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Genome-wide analysis the first to uncover a role for mutations in the noncoding portion of the genome in any human condition -
A new method for analyzing neural dynamics reveals that two regions involved in movement exhibit different patterns of activity, suggesting they perform different computations. -
The Simons Foundation is pleased to announce the appointment of Stéphane Mallat as Distinguished Research Scientist at the Center for Computational Mathematics (CCM) at the foundation’s Flatiron … -
Through inquiry-based, hands-on experiences, the Exploratorium has been changing the way its visitors view the world for decades. -
Through epigenetics, bad environments can have a lasting impact on the health of grandchildren and beyond. Neuroscientist Bianca Jones Marlin of the Simons Society of Fellows explores the … -
Family-organized groups are planning a number of meetings in 2019 for individuals with rare genetic neurodevelopmental conditions, including those due to 16p11.2 copy number variants and …
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The associate director of the Mathematics and Physical Sciences division describes some of the mysteries he hopes will be solved -
On April 17, 2018, molecular neuroscientists and geneticists gathered at the Simons Foundation for a workshop on the role of chromatin-associated proteins in autism spectrum disorder. The … -
SFARI is pleased to announce that it expects to have funded 22 grants in response to the Explorer Awards request for applications (RFA) this year. -
On May 15, 2018, SFARI convened a workshop to revisit the excitation/inhibition (E/I) hypothesis of autism, a synaptic-based account of the disorder that has been …