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Bringing people and ideas together to fund, conduct, and share transformative science.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. The Biggest Ideas in Math and Science: Quanta Magazine Releases Two Books

    November 20, 2018
    The magazine has released two collections of its award-winning reporting: “Alice and Bob Meet the Wall of Fire” and “The Prime Number Conspiracy.”
  2. Why Neuroscience Needs Data Scientists

    November 19, 2018
    Liam Paninski describes his efforts to process calcium imaging and other neural data, an effort that he hopes will help drive a new era of data sharing.
  3. Career Day Inverted: Students Glimpse STEM Careers in Action

    November 15, 2018
    During the STEM Matters NYC Career Day, high schoolers visited the Flatiron Institute to learn firsthand about the opportunities afforded by a science-centered education.
  4. The Genetic Riddle Wrapped in a Chromatin Mystery

    November 14, 2018
    The physical shape of chromatin, the molecular package holding DNA, affects the process of transcription and, ultimately, the expression of genes. Biochemist Takashi Onikubo of the Simons Society …
  5. Enormous ‘Ghost’ Galaxy Spotted on Outskirts of Milky Way

    November 13, 2018
    The newfound dwarf galaxy, Antlia 2, is the largest known satellite of the Milky Way and the sparsest galaxy ever seen.
  6. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    November 12, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  7. Sundance, Science Sandbox Announce Inaugural Science Nonfiction Film Grants

    November 8, 2018
    Five emerging filmmakers received grants and other critical support as part of a new program to elevate the voices of independent artists working at the intersection of science …
  8. Uncovering Serotonin Secrets in Muscle Movement

    November 8, 2018
    Better known for affecting mood, serotonin is also essential for motion. Neuroscientist Sara Fenstermacher of the Simons Society of Fellows explores how the chemical affects motor neurons and …
  9. Autism Innovative Medicine Studies-2-Trials (AIMS-2-Trials) — a European Initiative To Study Autism — Has Launched

    October 31, 2018
    The Innovative Medicines Initiative, a European public-private initiative, recently awarded a €115 million five-year grant for autism research. The Autism Innovative Medicine Studies-2-Trials (AIMS …
  10. A Conversation With Paul Wang, Deputy Director of Clinical Research Associates

    October 30, 2018
    Paul Wang, Deputy Director of Clinical Research Associates, L.L.C. (CRA), discusses the research that CRA supports, including human and animal studies using arbaclofen, a potential drug …
  11. Noise-Cancelling Method Enhances Ability To Predict Behavior from Brain Activity

    October 26, 2018
    A new technique that uses machine learning to mute noise inherent in single-trial neural recordings will make it easier to decipher the neural code
  12. Simons Variation in Individuals Project (Simons VIP): New Data Release

    October 25, 2018
    New Simons VIP Phase 2 data were recently added to SFARI Base. This data release included data from individuals with 16p11.2 copy number variants, 1q21.1 CNVs …
  13. DNA ‘Dances’ in First Explanation of How Genetic Material Flows Through a Nucleus

    October 25, 2018
    Finding reveals the large-scale movement of genetic material through the nucleus of a working cell.
  14. Neuroscience 2018: Presentations by SFARI Investigators

    October 24, 2018
    SFARI Investigators will be giving a number of presentations at Neuroscience 2018 in San Diego, CA (November 3–7).
  15. Watch: A Brooklyn Warehouse as a Crucible for New Ideas

    October 24, 2018
    Pioneer Works, a cultural center in Brooklyn, provides fertile ground for interdisciplinary interaction — and free science programming for the public.
  16. Pint-Size Planetary Systems Aren’t Into Heavy Metal

    October 24, 2018
    … type of planetary system, making them an ideal place to search for life on other planets. “Low-metallicity stars have been around a lot longer,” Brewer says …
  17. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    October 18, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  18. Beyond Movement: First Direct Evidence to Support Thinking in the Cerebellum

    October 18, 2018
    Best known for coordinating movement, the cerebellum is also essential for higher cognitive function.
  19. Visiting Researcher Program – Center for Computational Astrophysics

    October 10, 2018
    The Center for Computational Astrophysics (CCA) at the Simons Foundation’s Flatiron Institute invites researchers on sabbatical to visit the CCA in 2019–2020. Located in New York …
  20. Flatiron Institute Hosts National Science Foundation Workshop on the Plasma Physics of Neutron Star Mergers

    October 10, 2018
    … from around the world came together following the public announcement of the neutron star merger just a month earlier.
  21. SFN 2018 Presentations by SCGB Investigators and Collaborators

    October 8, 2018
    Traveling to the annual meeting in San Diego? Check out these talks.
  22. Singing Mice Hint at How Sensory Input Turns Into Behavior

    October 8, 2018
    At some point in a conversation, your cortex swings into action so you can respond to what you’ve heard. To understand this sensorimotor transformation, Arkarup Banerjee of …
  23. Flatiron Institute Launches Center for Computational Mathematics

    October 1, 2018
    … units came up with computational mathematics, I was dubious at first but was gradually persuaded that such a unit would act like glue, holding the whole institute …
  24. Rediscovering Emotion in the Brain

    October 1, 2018
    The neuroscience of emotion needs a common framework — one that spans research in both people and animals.
  25. Watch: Simulations of Stellar Geysers from Luminous Blue Variable Stars

    September 26, 2018
    Massive outbursts from stellar giants known as luminous blue variables have puzzled scientists. New 3-D simulations hint at a mechanism
  26. Elusive Origin of Stellar Geysers Revealed by 3D Simulations

    September 26, 2018
    Supersize eruptions of some of the biggest, brightest stars in the universe result from clumps of helium-rich material launched spaceward by intense light, simulations suggest
  27. Gaia Data Releases Spark Open-Access Success

    September 24, 2018
    Thanks to the Gaia team’s immediate release of all its Milky Way measurements, data sprints at the Flatiron Institute quickly uncovered new discoveries
  28. CCQ Director Antoine Georges Receives Honorary Degree

    September 22, 2018
    On September 22, 2018, Antoine Georges, the director of the Flatiron Institute’s Center for Computational Quantum Physics, was awarded an honorary doctorate of science from the University …
  29. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    September 19, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  30. Particles Surf Their Own Waves, Reveal How Microbes and Cells Move Through Human Body

    September 17, 2018
    New calculations and experiments show how balls ‘catch a wave’ when falling through viscous liquid near a flexible rubber sheet
  31. SFARI Workshop Discusses Zebrafish As Experimental Systems To Study Autism

    September 11, 2018
    On January 26, 2018, SFARI held a workshop to discuss the use of zebrafish in autism research. Experts in both rodent and fish models discussed key issues in …
  32. SFARI 2018 Pilot and Research Awardees Announced

    September 10, 2018
    SFARI is pleased to announce that it intends to fund 36 grants (15 Pilot Awards and 21 Research Awards) in response to the 2018 Pilot and Research Awards …
  33. SFARI Spring 2018 Science Meeting Discussed Latest Developments in Autism Research

    September 7, 2018
    SFARI held its thirteenth science meeting April 8–12, 2018. SFARI investigators, collaborators and foundation staff came together to discuss recent findings in autism genetics, molecular and system …
  34. Secret to Fruit Fly Attraction Traced to Subtle Electrical Changes

    August 31, 2018
    An innovative study comparing neural circuitry in two species of fruit fly reveals why they prefer members of their own clan.
  35. Watch: Journey of Women in Mathematics

    August 28, 2018
    Three women mathematicians were celebrated during the inaugural World Meeting for Women in Mathematics, or (WM)²
  36. “The Most Unknown” Available on Netflix, Youtube

    August 24, 2018
    The Science Sandbox-supported feature documentary is now available on Netflix, with a related series on Youtube.
  37. SFARI Gene: New Data Release

    August 17, 2018
    New data were added to SFARI Gene in August 2018. This data release included updated gene scores for candidate autism risk genes, as well as the addition of …
  38. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    August 13, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  39. Leelavati Prize Winner Ali Nesin: A Fighter for Math’s Next Generation

    August 9, 2018
    Despite police raids, threats of arrest and a shortage of resources, mathematician Ali Nesin has built an oasis for math education in rural Turkey. For his efforts, he …
  40. Radiolab Tackles the Epic Journey of Reproduction

    August 8, 2018
    “Gonads,” a six-part series from Radiolab and producer Molly Webster, examines the incredible processes that occur within us in order to continue our species.
  41. Chern Medal Video: Masaki Kashiwara and 50 Years of Foundational Math

    August 6, 2018
    The 2018 Chern medal is awarded to Masaki Kashiwara for his outstanding and foundational contributions to algebraic analysis and representation theory sustained over a period of almost 50 …
  42. Gauss Prize Video: David Donoho and the Unreasonable Effectiveness of Mathematics

    August 6, 2018
    David Donoho of Stanford University is award the 2018 Gauss Prize for his fundamental contributions to the mathematical, statistical and computational analysis of signal processing
  43. Systems Neuroscience Is About to Get Bonkers

    August 3, 2018
    The advent of inexpensive, high-quality recording equipment and the maturation of deep learning present an incredible opportunity for neuroscience; but the field needs to develop theoretical frameworks …
  44. Duck Versus Catch: How the Brain Rapidly Responds to Context

    August 2, 2018
    The brain represents different contexts by confining neural activity to parallel landscapes.
  45. Fields Medal Video: Peter Scholze

    August 1, 2018
    Peter Scholze of the University of Bonn receives the award for transforming arithmetic algebraic geometry over p-adic fields through his introduction of perfectoid spaces and for the …
  46. Fields Medal Video: Akshay Venkatesh

    August 1, 2018
    Akshay Venkatesh of Stanford University and the Institute for Advanced Study synthesized analytic number theory, homogeneous dynamics, topology and representation theory.
  47. Fields Medal Video: Caucher Birkar

    August 1, 2018
    Caucher Birkar of the University of Cambridge proved the boundedness of Fano varieties and contributed to the minimal model program.
  48. Fields Medal Video: Alessio Figalli

    August 1, 2018
    Alessio Figalli of ETH Zurich contributed to the theory of optimal transport, which has applications in partial differential equations, metric geometry and probability.
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