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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Andrew Millis to Receive Hamburg Prize for Theoretical Physics

    July 13, 2017
    … looking forward to many stimulating discussions with him,” says Klaus Sengstock, head of the jury and spokesperson of the cluster of excellence CUI at Universität Hamburg. Millis …
  2. Angel Rubio Appointed as CCQ Distinguished Research Scientist

    July 6, 2017
    The Simons Foundation is pleased to announce the appointment of Angel Rubio as distinguished research scientist at the Center for Computational Quantum Physics (CCQ) at the foundation’s …
  3. A Dopamine Dial for Controlling Neural Variability

    July 5, 2017
    The discovery of a new kind of neuron in the bird brain reveals a potential mechanism for controlling variation in zebra finch song.
  4. SFARI July 2017 announcements: Bridge to Independence Award RFA, Recruiting SPARK participants into new research studies and more

    July 1, 2017
    This issue of the SFARI newsletter includes: (1) 2017 Bridge to Independence Award request for applications, (2) Application process for recruiting SPARK participants into new research studies is …
  5. Working-Memory Research Uncovers Essential Role for Thalamus

    June 27, 2017
    Previous research suggests that the neural signals underlying working memory reside in the cortex. But the new findings suggest the thalamus is a vital contributor.
  6. A Conversation with SFARI Bridge to Independence Investigator Sung Han

    June 23, 2017
    SFARI Investigator Sung Han discusses his lab’s work and how the Bridge to Independence Award helped him launch his independent career in autism research.
  7. SPARK: Research matching program launched

    June 16, 2017
    SFARI is pleased to announce that SPARK has launched its research matching program, through which researchers can apply to recruit the SPARK cohort into new research studies. Researchers …
  8. Science Lives: Mathematician William Browder (1934–2025)

    June 14, 2017
    William Browder is a mathematician at Princeton University who has made important breakthroughs in topology and geometry. He is best known as one of the inventors of surgery …
  9. Untangling Neurons

    June 13, 2017
    Networks of neurons in the motor cortex may generate extra dimensions of information in order to create unambiguous motor plans
  10. From the bioRxiv: A Selection of Recently Posted Papers from SCGB Investigators and Others

    June 13, 2017
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  11. New Collaboration on Theory of Microbial Ecosystems Launched

    May 30, 2017
    The multi-year collaboration will investigate how communities of marine microbes form and function.
  12. The Dimension Question: How High Does It Go?

    May 24, 2017
    How many cells do neuroscientists need to monitor to get an accurate picture of what the brain is doing?
  13. The Heroes of the Billion Oyster Project

    May 22, 2017
    Photographer Ben Von Wong profiles the students at New York Harbor School who are contributing to the Billion Oyster Project.
  14. A SFARI channel on bioRxiv

    May 12, 2017
    A SFARI channel now exists on bioRxiv, one of the most used preprint servers for biology. This channel should help readers to find preprints reporting SFARI-funded research …
  15. From the bioRxiv: A Selection of Recently Posted Papers from SCGB Investigators and Others

    May 11, 2017
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  16. Watch: Kishore Hari on Science Sandbox

    May 10, 2017
    The Science Sandbox Advisory Board reacts to the team’s mission
  17. In Search of the Cogwheels of the Brain

    May 10, 2017
    Mehrdad Jazayeri says researchers need to think carefully about what it means to do causal neuroscience.
  18. SFARI May 2017 announcements: SPARK update, new SSC data, IMFAR and more

    May 9, 2017
    This issue of the SFARI newsletter includes: (1) SPARK update, (2) Simons Simplex Collection: Updated medical and educational data now available, (3) SFARI Gene: New data available, (4 …
  19. Simons Simplex Collection: Updated medical and educational data now available

    May 5, 2017
    Updated medical, developmental and educational outcomes information on a subset of families who participated in the Simons Simplex Collection (SSC) — a total of 440 families — is now available …
  20. When Less is More: Sparse Networks Can Outperform Dense Ones

    May 5, 2017
    Despite a paucity of synapses, granule-cell networks can encode rich information.
  21. New Quanta Magazine Website Launched

    May 2, 2017
    Along with a new logo, the changes reflect the growth of the magazine’s editorial offerings and brand
  22. IMFAR 2017: Presentations by SFARI Investigators

    April 28, 2017
    Presentations that will be given by SFARI Investigators at the 2017 International Meeting for Autism Research (IMFAR) in San Francisco (May 10-13) are highlighted.
  23. SFARI Gene: New data release

    April 28, 2017
    New data were added to SFARI Gene in March 2017. This data release included updated gene scores for candidate autism risk genes, new animal models, and new copy …
  24. Simons Grantees Elected to the American Academy of Arts and Sciences 2017 Class

    April 17, 2017
    … citation. Charles S. Craik, a chemist at the University of California, San Francisco and SFARI investigator. He has made pioneering contributions to understanding the structure and function …
  25. New 2018 Funding Announced for Africa Mathematics Project

    April 17, 2017
  26. Simons Foundation Launches New Postdoctoral Fellowship in Marine Microbial Ecology

    April 13, 2017
    The Simons Foundation is now accepting applications for postdoctoral fellowships to support research on fundamental problems in marine microbial ecology. The foundation is particularly interested in applicants with …
  27. Four Scientists Named 2017 Simons Early Career Investigators in Marine Microbial Ecology and Evolution

    April 13, 2017
    The Simons Foundation has named four scientists as 2017 Simons Early Career Investigators in Marine Microbial Ecology and Evolution. The three-year awards are intended to help launch …
  28. New Concepts and Computational Methods To Tackle Quantum Nature of Matter

    April 11, 2017
    How do electrons flow during photosynthesis? Why do materials superconduct? How do you design a better battery? A new Flatiron Institute center will develop the conceptual and algorithmic …
  29. Surprising Codes for Innate Behavior

    April 11, 2017
    Despite very different wiring patterns, two brain regions involved in learned and innate olfactory behavior encode information in similar ways.
  30. From the bioRxiv: A Selection of Recently Posted Papers from SCGB Investigators and Others

    April 6, 2017
    …  [Abstract] [PDF] Biases in multivariate neural population codes Sander Keemink and Mark van Rossum bioRxiv posted 4 March 2017 [Abstract] [PDF]
  31. Coming Soon: Routine Recording From Thousands of Neurons

    April 6, 2017
    New electrode technologies dramatically increase the number of cells and length of time that scientists can record from the brain.
  32. The Hippocampus Maps More Than Space

    March 29, 2017
    New research shows that the hippocampus can map sound, supporting a broader role for this brain region in organizing information.
  33. Let’s Go Tardigrading: What a Hardy Microscopic Animal Can Teach Us About Scientific Thinking

    March 27, 2017
    As part of the launch of the Science Sandbox initiative, the team made a video about tardigrades and the power of thinking like a scientist.
  34. Deciphering Scent: How We Untangle the Tapestry of Odors

    March 23, 2017
    A probabilistic approach helps to explain how the brain might identify individual odors in an environment with multiple smells.
  35. Neurons in Cerebellum Show Surprising Activity During Learning

    March 21, 2017
    The study, the first to look at the cerebellum’s granule cells in living animals while they learn a task, reveals that the cells not only relay sensory …
  36. How Supermassive Black Holes Can Form Without Collapsing Stars

    March 17, 2017
    New simulations reveal that proto-galaxies may work together to create hefty direct-collapse black holes.
  37. From the bioRxiv: A Selection of Recently Posted Papers from SCGB Investigators and Others

    March 15, 2017
    … Humphries bioRxiv posted 1 February 2017 [Abstract] [PDF] SkinnerTrax: high-throughput behavior-dependent optogenetic stimulation of Drosophila Ulrich Stern and Chung-Hui Yang bioRxiv posted 1 February …
  38. Flatiron Institute to Repurpose ‘Gordon’ Supercomputer at UC San Diego

    March 15, 2017
    The powerful resource from the San Diego Supercomputer Center will be used for astrophysics, biology and materials research.
  39. Science Lives: Mathematician Elias Stein (1931–2018)

    March 13, 2017
    Elias Stein, a professor emeritus of mathematics at Princeton University, is a leading figure in the field of harmonic analysis. He is best known for his contributions to …
  40. Noninvasive Tool Controls Neurons

    March 13, 2017
    A genetically engineered nanoparticle allows scientists to turn brain cells on and off with radio waves.
  41. Meet the Most Abundant Photosynthesizing Cell in the Ocean

    March 10, 2017
    Prochlorococcus influences climate, ocean ecosystems and perhaps even evolution.
  42. Special Holonomy in Geometry, Analysis and Physics

    March 9, 2017
    This collaboration will advance the theory and applications of spaces with special holonomy and the geometric structures—calibrated submanifolds and instantons—associated with them, particularly in the two …
  43. The Eternal Sky: A Short Film About Building the Simons Observatory (Part 1)

    March 8, 2017
    By looking for signs of cosmic inflation, the Simons Observatory will answer questions about the origin of the universe. First in a series.
  44. Major Pledge Will Boost Brain Research into Causes of Autism

    March 7, 2017
    The Simons Foundation Initiative for the Developing Brain will be launched at the University of Edinburgh.
  45. Crowdsourcing Expertise

    March 1, 2017
    By hosting a Wikipedia ‘edit-a-thon’ at a science conference, you can instantly share your research knowledge with millions while improving the science content on the most …
  46. Mind the Gaps: Improving the Science on Wikipedia

    March 1, 2017
    The Wikipedia Year of Science aims to rethink college class assignments and coordinate mass editing sessions to fill critical gaps on the site’s science coverage
  47. Epigenetic mechanisms beyond imprinting are widespread in the mammalian brain

    February 28, 2017
    Christopher Gregg and colleagues demonstrate that diverse epigenetic mechanisms affect allele-specific gene expression in the mammalian brain.
  48. Scientific Speed Dating at Cosyne 2017

    February 28, 2017
    Theorists and experimentalists searched for compatible mates.
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