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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Bayes Reading Group: Brian Trippe (Columbia)

    Meeting
    Discussion Lead: Brian Trippe (Columbia) Title: “For high-dimensional hierarchical models, consider exchangeability of effects across covariates instead of across datasets” Abstract: Hierarchical Bayesian methods enable information sharing …
  2. Genomics Group Meeting

    Meeting
  3. Systems Biology Group Meeting

    Meeting
  4. CCB Seminar: A computational perspective on cytoskeletal self-assembly processes across scales: from the mitotic spindle to protein-membrane interactions (Chris Edelmaier, Ph.D., University of North Carolina)

    Meeting
    Speaker: Chris Edelmaier, Ph.D. (University of North Carolina) Topic: A computational perspective on cytoskeletal self-assembly processes across scales: from the mitotic spindle to protein-membrane interactions …
  5. CCM Colloquium: Timo Betcke (University College London )

    Event
  6. Structural and Molecular Biophysics Group Meeting

    Meeting
  7. SCDG: open discussion

    Event
    Please bring a numerical question if you have one. Visitors: Timo Betcke (UCL) Anna Broms (KTH) Note we’re in the small conference room now; you’ll want …
  8. Biophysical Modeling Group Meeting

    Meeting
  9. Developmental Dynamics Group Meeting

    Meeting
  10. Hack the Hackathon

    Event
  11. Flatiron Institute Seminar Series: Shirley Ho

    Seminar
    Title: Using Deep Learning as a Last Resort?! Abstract: For the last 10 years, we have seen a rapid adoption of deep learning techniques across many disciplines, ranging …
  12. Bayes Reading Group: Charles Margossian

    Meeting
    Discussion Lead: Charles Margossian [CCM] Topic: The Revenge of nested R-hat Abstract: I’ll present a major revision of the nested Rhat preprint (https://arxiv.org/abs …
  13. CCN Seminar with Guest Speaker Amy Christensen (Washington University in St. Louis)

    Lecture
    … equations of a sparse, low-dimensional dynamical system that could generate interpretable single trial, cluster-averaged activity. Our findings reveal a dynamical system underlying a decision process …
  14. CCB Brown Bag Seminar

    Meeting
    Presenter: Julia Koehler Leman (Research Scientist, Systems Biology) Presenter: Tatyana Gavrilchenko (Flatiron Research Fellow, Developmental Dynamics)
  15. 2022 Mathematical and Scientific Foundations of Deep Learning Annual Meeting

    Conference
    … shed light on representation learning and memorization in deep learning, but might also have negative potential implications on privacy; (3) In certain settings, the implicit bias provably …
  16. CCM Colloquium: Karsten Urban (Ulm)

    Event
  17. 2022 Simons Society of Fellows Alumni Symposium

    Conference
    … the Interrogation of Complex Disease Silvana Konermann Assistant Professor at Stanford University and the founding director of Arc Institute View Slides (PowerPoint) September 28, 2022 Asher J …
  18. NeuroDataReHack: Generating new insights from existing neurophysiology data through secondary analysis

    Related
    September 28th, 2022: Virtual Data Showcase October 3-5, 2022: Allen Institute, Seattle, WA, USA The DANDI Archive now has over 90 publicly available neurophysiology datasets, standardized using …
  19. Systems Biology Group Meeting

    Meeting
  20. Structural and Molecular Biophysics Group Meeting

    Meeting
  21. Quantum Cafe: Sebastian Will

    Colloquium
    Title: Synthetic Dipolar Quantum Matter Abstract:It has been a long quest in ultracold quantum science to realize many-body systems with strong and tunable long-range interactions …
  22. CCN Seminar with Talmo Pereira (Salk Institute)

    Lecture
    Talk Title and Abstract to be announced Organizer: Center for Computational Neuroscience
  23. Biophysical Modeling Group Meeting

    Meeting
  24. Lectures on Diagrammatic Monte Carlo: Simulating Magnetic Phases with Real-Space Dynamical Mean Field Theory (Robert Peters)

    Lecture
    … Exchange-correlation effects in a warm dense electron gas (Pengcheng Hou); January 24, 2023: Study of the real frequency dependence of the optical conductivity in the 2D …
  25. Neuroscience and Artificial Intelligence

    Related
    This meeting brings some of the top global researchers at the interface of neuroscience and AI to the University of Washington. The 4-day meeting will feature sessions …
  26. Neuromatch Conference

    Related
    The Neuromatch Conference is focused on Computational Neuroscience broadly construed, following in the model of the first two NMC events. The scope includes machine learning work that has …
  27. Mechanisms of Aging

    Related
    The meeting will explore the regulation and function of genes and processes that are now known or suspected to control cellular and/or organismic aging. Abstract Deadline: July …
  28. Developmental Dynamics Group Meeting

    Meeting
  29. The Assembly and Function of Neural Circuits

    Related
    The Ascona 2022 Neuronal Circuits Meeting will present work on how specific neuronal circuits encode information and drive behavior, on how brain systems interact to produce specific functions …
  30. CCA Colloquium: Mariangela Lisanti

    Event
    CCA Colloquium: Mariangela Lisanti Title: Galactic Probes of Fundamental Dark Matter Physics Abstract: The hypothesis of Cold Dark Matter (CDM) has been spectacularly confirmed on the largest scales …
  31. Bayes Reading Group: Theo Moins [INRIA, France]

    Meeting
    Discussion Lead: Theo Moins [INRIA, France] Topic: On the use of a local R-hat to improve MCMC convergence diagnostic Abstract: Diagnosing convergence of Markov chain Monte Carlo …
  32. In search of causality: From neuropsychiatric genetics to pathophysiology

    Conference
    On September 23, 2022, SFARI will co-host a virtual workshop about the causal mechanisms underlying neuropsychiatric conditions, from genes to cells to circuits to behavior. The event …
  33. IDEAS Scholar Lecture/CCB Colloquium: "Computational challenges in a densely sequenced tree of life"

    Colloquium
    Speaker: Dr. Katherine S. Pollard (University of California, San Francisco) Title: Computational Challenges in a densely sequenced tree of life Genome sequencing and assembly have exploded since 2015 …
  34. CCN Seminar with C. Shan Xu (Yale University)

    Seminar
    Please join us for a CCN Seminar with C. Shan Xu, Harvey and Kate Cushing Professor of Physiology in the Department of Cellular and Molecular Physiology at Yale …
  35. Systems Immunology in Aging and Complex Diseases

    Related
    Disruption of immune cell functions and responses plays a significant role in the etiology of many aging-related diseases. Recent advances in genomic technologies enable precise description of …
  36. Algorithmic Fairness from a Sociotechnical Lens

    Lecture
    Books, films and television increasingly portray artificial intelligence as poised to reshape modern society. Yet many real-world AI systems deployed so far have manifested salient societal risks …
  37. CCM Colloquium: Brendan Meade (Harvard)

    Event
  38. Structural and Molecular Biophysics Group Meeting

    Meeting
  39. Structural and Molecular Biophysics Group Meeting

    Meeting
  40. CCN Seminar with Alon Rubin (Weizmann Institute)

    Seminar
    Please join us for a CCN Seminar with Alon Rubin, Staff Scientist, Weizmann Institute of Science, Israel Title: Representational Drift in Hippocampus and Cortex Abstract: Recent studies revealed …
  41. SCS:

    Event
  42. Biophysical Modeling Group Meeting

    Meeting
  43. SCS: Brendan Meade (Harvard): boundary integral for elastostatics, earthquakes.

    Event
  44. QMC in the Next Decade

    Workshop
    … Hubbard model: ground state phase diagram Paul Yang Itinerary magnetism in moiré heoterobilayer September 20, 2022 David Ceperley: Prospects for Continuum Quantum Monte Carlo September 20, 2022 …
  45. Developmental Dynamics Group Meeting

    Meeting
  46. Systems Biology Group Meeting

    Meeting
  47. Reionization on a Blackboard

    Event
    The aim of this 4-day workshop is to discuss four timely topics at the forefront of current research on the Epoch of Reionization. The meeting will move …
  48. Reporting in the Margins of Error

    In Conversation
    … into 14 languages. Angela has a master’s in engineering from the University of Oxford and was a fellow at the Massachusetts Institute of Technology.
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