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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

Discover the latest news, research, and updates.

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We convene scientists, mathematicians, and thinkers to share ideas and explore new questions.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

Work with us on the frontier of basic science research.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Genomics Group Meeting

    Meeting
  2. LCV Lab Meeting

    Meeting
  3. CCM Colloquium: Matt Hoffman (Google)

    Event
    ML, neural nets, Hamiltonian Monte Carlo, parallelization If you would like to attend, please email [email protected] for the Zoom details.
  4. Mechanics of Life Workshop

    Workshop
    … (University of Pennsylvania) Nicolas Romeo (Massachusetts Institute of Technology) David Saintillan (University of California, San Diego) Joshua W. Shaevitz (Princeton University) Michael Shelley (Center for Computational Biology …
  5. Electron Microscopy Interest Group Meeting

    Meeting
    Are you interested in electron microscopy? Do you use or analyze cryo-electron- tomography data? Are you developing methods for single particle analysis? Have you just started studying …
  6. Developmental Dynamics Group Meeting

    Meeting
  7. Biophysical Modeling Group Meeting

    Meeting
    Presenter: Will Conway (Harvard University) Title: Biophysics of kinetochore microtubules in human mitotic spindles Abstract: During eukaryotic cell division, microtubules bind to a macromolecular complex on the surface …
  8. The Sticky Space Between Art and Science

    In Conversation
    … Ph.D. in physics from the University of Colorado Boulder. Laura Splan is a transdisciplinary artist working at the intersections of science, technology, and culture. Her research …
  9. CCN Spring Reception

    Meeting
  10. CCA Colloquium: Erika Hamden

    Event
    CCA Colloquium: Erika Hamden Title: Exploring the diffuse universe in the space ultraviolet Abstract: The ultraviolet is experiencing a boom of interest, resulting in exciting mission developments in …
  11. Vision Journal Club: Guest Speaker, Robert Geirhos

    Lecture
  12. CCB Seminar: "Stability in the Face of Change: How Hormones Regulate and Coordinate Growth Across Environmental Conditions in Drosophila" (Alexander Shingleton, Ph.D., University of Illinois-Chicago)

    Seminar
    … different environmental conditions. Ultimately, our goal is to better understand how plasticity and robustness are achieved by the same developmental system, so that developing animals phenotypically match …
  13. Genomics Group Meeting

    Meeting
  14. CCB Seminar: "Inter-organ communication: A Drosophila perspective" (Norbert Perrimon, PhD, Harvard Medical School)

    Seminar
    Speaker: Norbert Perrimon, Ph.D., Professor of Genetics, Blavatnik Institute, Harvard Medical School Topic: Inter-organ communication: A Drosophila perspective Mathematical modelling has become increasingly integrated into biological …
  15. CCB Seminar: "Motility and morphodynamics of confined cells" (Ido Lavi, University of Barcelona)

    Seminar
    Speaker: Ido Lavi, University of Barcelona Title: Motility and morphodynamics of confined cells Under physiological conditions, immune cells and cancer cells typically move through highly restricted 3D environments …
  16. LCV Lab Meeting

    Meeting
  17. CCM Colloquium: Barry Smith (CCM)

    Event
    Title and abstract TBD If you would like to attend, please email [email protected] for the Zoom details.
  18. CCB Colloquium: "Life in a Tight Spot: How Bacteria Swim, Disperse, and Grow in Crowded Spaces" (Sujit Datta, Ph.D., Princeton University)

    Colloquium
    … Harvard, where he studied fluid dynamics and instabilities in porous media and colloidal microcapsules with David Weitz. His postdoctoral training was in Chemical Engineering at Caltech, where …
  19. American Aging Association AGE

    Related
    The 2022 AGE Meeting will feature speakers and organizations representing areas of major advance in aging and age-associated disease that made recent highly impactful contributions and have …
  20. CCB Seminar: "An overview of the dragonfly and damselfly tree of life" (Jessica Ware, Ph.D., American Museum of Natural History)

    Seminar
    Speaker: Jessica Ware, American Museum of Natural History, Curator of Odonata & non-Holometabolous Minor Orders Topic: An overview of the dragonfly and damselfly tree of life Dragonflies and …
  21. Developmental Dynamics Group Meeting

    Meeting
  22. Systems Biology Group Meeting

    Meeting
  23. Astronomical Software Development

    Event
  24. Amplitudes Meet Cosmology (2022)

    Symposia
    … Jaroslave Trnka | Amplitudes Introduction 5:00 – 6:00 PM Dionysios Anninos | de Sitter Musings 6:15 – 7:15 PM Austin Joyce | An Invitation to the Cosmological Bootstrap …
  25. Flatiron Institute Seminar Series: Brato Chakrabarti

    Lecture
    Title: The waves within us Abstract: An important class of microscale fluid-structure interactions in biology involve the interactions and deformations of flexible elasticae, both passive and active …
  26. Bayes Reading Group: Manushi Welandawe & Jonathan Huggins [Boston Uni]

    Event
  27. SCGB/CCN Lecture Series & Reception

    Lecture
  28. Genomics Group Meeting

    Meeting
  29. Transgenerational Inheritance of Pathogen Avoidance or: How Getting Food Poisoning Might Save Your Species

    Lecture
    Our experiences influence our decisions, but can they influence our descendants’ decisions? Animals must distinguish pathogens from nutritious food sources; this is particularly challenging for C. elegans, which …
  30. LCV Lab Meeting

    Meeting
  31. CCM Colloquium: Adrianna Gillman (CU Boulder)

    Event
    Title: An efficient and high order accurate solution technique for variable coefficient elliptic partial differential equations For many applications in science and engineering, the ability to efficiently and …
  32. (CANCELLED) FI Computational Methods and Data Science Journal Club: Bamdad Hosseini

    Seminar
    FI Computational Methods and Data Science Journal Club Flatiron Institute, 162 5th Avenue Speaker: Bamdad Hosseini (UW) Title: Bayesian inference of functions: from theory to computations Abstract: Bayesian …
  33. CCB Colloquium: "The mechanics of bio-inspired material intelligence" (Markus J. Buehler,Ph.D.)

    Colloquium
    Speaker: Markus J. Buehler McAfee Professor of Engineering, MIT Title: The mechanics of bio-inspired material intelligence Digital biomaterials are designed through an integrated approach of large-scale …
  34. Developmental Dynamics Group Meeting

    Meeting
  35. Systems Biology Group Meeting

    Meeting
  36. Biophysical Modeling Group Meeting

    Meeting
    Presenter: Brato Chakrabarti Title: The waves within us An important class of microscale fluid-structure interactions in biology involve the interactions and deformations of flexible elasticae, both passive …
  37. 𝑝-adic Hodge Theory (2022)

    Symposia
    … elliptic curves over imaginary quadratic fields, which also builds on recent work of Allen-Khare-Thorne. Laurent Fargues Extension du domaine de la lutte I will explain …
  38. CCA Colloquium: Dan Kasen

    Event
    CCA Colloquium: Dan Kasen Title: Signals from Black Hole + Neutron Star Mergers Abstract: Gravitational wave observations from the last LIGO/VIRGO run appeared to detect mergers between a …
  39. Computer Vision Interest Group Seminar: "Neurotransmitter Classification from Electron Microscopy" (HHMI Janelia)

    Seminar
    Speaker: Jan Funke, Group Leader at HHMI Janelia Topic: Neurotransmitter Classification from Electron Microscopy In this talk, we will have a look at our ongoing work to discover …
  40. Genomics Group Meeting

    Meeting
  41. Robust and Equitable Uncertainty Estimation

    Lecture
    Machine learning provides us with an amazing set of tools to make predictions, but how much should we trust particular predictions? To answer this, we need a way …
  42. PI Monthly Meeting

    Meeting
  43. LCV Lab Meeting

    Meeting
  44. Neuronal Ensembles 2022

    Related
    The symposium, hosted by the NeuroTechnology Center at Columbia University, will feature talks from leading investigators in the fields of developmental neuroscience, sensory neuroscience, neural cognition, and computational …
  45. Systems Biology Group Meeting

    Meeting
  46. Biophysical Modeling Group Meeting

    Meeting
    Presenter: Alex Rautu Title: Active hydrodynamics of nucleoplasm We describe an active hydrodynamic model of chromatin within eukaryotic cells. Viscoelastic properties of the euchromatin and heterochromatin are both …
  47. CCQ Current and Past Quantum Cafe Schedules

    Colloquium
  48. Periods and L-values of Motives (2022)

    Symposia
    … notion of an Euler system, and the role these objects play in proving cases of the Bloch–Kato conjecture and Iwasawa main conjecture; and I will survey …
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