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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Black Hole Discoveries Abound in Newly Released LIGO-Virgo Catalog

    May 26, 2026
    Observations of colliding black holes from the LIGO-Virgo-KAGRA collaboration are shedding new light on the universe’s darkest inhabitants as well as on the nature of …
  2. Simons Award Manager (SAM) FAQ and Instructional Videos

    … other support records will not be saved to your SAM profile. To save these records to your profile, please navigate to “Profiles” in the gray navigation panel …
  3. Early Eukaryotes Used Oxygen at the Seafloor

    The Scientist
    Combining fossil and geochemical analysis, researchers showed that eukaryotic cells were already complex and aerobic 1.7 billion years ago, pushing back the dawn of eukaryogenesis.
  4. Watch: A Short Film About a Scientist and a Microscopic Being

    May 20, 2026
    Flatiron Institute computational biologist Sonya Hanson and filmmaker Diego Murillo collaborated on a short film that examines the strange resilience of the tardigrade.
  5. Hidden Patterns: Kevin Hu Navigates the Mathematics of Disordered Systems

    May 19, 2026
    Simons Society of Fellows Junior Fellow Kevin Hu explains how coin flips and balls rolling downhill relate to complex problems in probability and mathematical physics.
  6. Alumni Spotlight: Gokberk Kabacaoglu

    May 15, 2026
    Kabacaoglu, a former research fellow at the Simons Foundation’s Flatiron Institute, is now an assistant professor in the Department of Computer Science at Durham University in England …
  7. Now Accepting Applications for Workshops on Quantitative Behavioral Phenotyping in Autism

    May 14, 2026
    The Simons Foundation Autism Research Initiative will hold three workshops aimed at developing a multiyear collaborative effort in quantitative behavioral analysis of individuals with autism.
  8. Alumni Spotlight: Christopher Lam

    May 13, 2026
    A former Flatiron Institute pre-doctoral fellow, Lam now works on the Nancy Grace Roman Space Telescope.
  9. Watch: A Short Film on the Secret Life of Electrons and the Power of a Collective

    May 13, 2026
    Flatiron Associate Research Scientist Olivier Gingras and filmmaker Yan Shao collaborated on a film exploring the transition of a single electron to the collective state of superconductivity.
  10. Seeing and Imagining Are Handled by the Same Brain Cells

    May 12, 2026
    Researchers make advances in understanding how human brains are wired by pinning down how the same neurons are used for both imagining and seeing objects.
  11. Unbiased Approaches to Quantifying Motor and Other Visible Behaviors in Humans With Autism

    May 11, 2026
    On January 22–23, 2026, SFARI held a workshop to explore advanced quantitative phenotyping methods for capturing visible behaviors, including motor phenotypes.
  12. Alumni Spotlight: Ryan Levy

    May 8, 2026
    A former Flatiron Institute research fellow, Levy now explores how fault-tolerant quantum computers can advance basic research.
  13. Watch: 5 Math-Inspired Short Films Created by Flatiron Institute Researchers and Filmmakers

    May 6, 2026
    As part of the Simons Foundation’s Infinite Sums initiative, the 2026 Symbiosis program produced five experimental short films rooted in mathematics.
  14. Alumni Spotlight: Jamie Morton

    May 6, 2026
    Collaborations during Morton’s time as an associate research scientist at the Simons Foundation’s Flatiron Institute inspired his new startup.
  15. Black Holes

    Black Holes Understanding the universe’s most extreme objects
  16. How We Make Grants

  17. Our Impact

  18. For Every Patient Their Own Drug

    Nautilus
    Patients with exceedingly rare genetic diseases fall through the cracks of the medical system. This doctor is designing drugs for them, one at a time.
  19. AI Will Be Top of Mind at ICM, Math’s Biggest Conference

    May 4, 2026
    The International Congress of Mathematicians, coming to Philadelphia this summer, includes panels and talks about artificial intelligence and the humanity of the field.
  20. Applications for 2027 Simons Graduate Fellowships in Ecology and Evolution Now Open

    May 1, 2026
    The Simons Foundation’s Life Sciences division is now accepting applications for its 2027 Simons Graduate Fellowships in Ecology and Evolution. The application deadline is June 30, 2026 …
  21. CCN Director Eero Simoncelli Elected to National Academy of Sciences

    April 29, 2026
    Eero Simoncelli, director of the Flatiron Institute’s Center for Computational Neuroscience (CCN), has been elected to the National Academy of Sciences. He joins 119 national and 25 …
  22. New Ideas: Applications Open for Exploratory Autism Research Grants

    April 29, 2026
    To enable bold and innovative new directions in autism research, the Simons Foundation Autism Research Initiative (SFARI) welcomes applications for its recently launched New Ideas grant program. These …
  23. New Ideas RFA: Perspectives

    April 29, 2026
    … rigor, proposals are evaluated on how clearly they articulate their relevance to autism and related NDDs. We encourage applicants to familiarize themselves with the current landscape of …
  24. Pilar Cossio: Reconstructing RNA’s Shapeshifting Behavior

    April 28, 2026
    Flatiron Institute Senior Research Scientist Pilar Cossio builds tools to analyze experimental measurements and reveal how environmental changes alter the behavior of RNA molecules.
  25. American Academy of Arts and Sciences Elects CCM’s Charles Epstein

    April 23, 2026
    Mathematician Charles Epstein of the Simons Foundation’s Flatiron Institute was elected to the American Academy of Arts and Sciences on April 22. He joins leaders in the …
  26. Moduli of Varieties

    Simons Collaboration
    This collaboration advances the classification of algebraic varieties, a central problem in algebraic geometry.
  27. Extreme Wave Phenomena Based on Symmetries

    Simons Collaboration
    This collaboration, directed by Andrea Alù of the Advanced Science Research Center at The Graduate Center, CUNY, develops metamaterials with novel wave-manipulation capabilities.
  28. Celestial Holography

    Simons Collaboration
    This collaboration, directed by Andrew Strominger of Harvard University, advances the holographic principle in asymptotically flat spacetimes.
  29. Global Brain

    Simons Collaboration
    The Simons Collaboration on the Global Brain aims to expand our understanding of the role of internal brain processes in the arc from sensation to action, thereby discovering …
  30. Black Holes and Strong Gravity

    Simons Collaboration
    This collaboration, directed by Nicolás Yunes at the University of Illinois Urbana-Champaign, studies strong gravity through theory and gravitational observations.
  31. Samir Patel on Science Journalism and Curiosity

    The Chronicle
    On April 19, Humanities in Medicine, the Duke Program in Literature, the DeWitt Wallace Center, Duke English and Duke’s Program in Education hosted “Storytelling Through Science Journalism …
  32. Announcing the Recipients of the 2025 Data Analysis Awards

    April 21, 2026
    The Simons Foundation Autism Research Initiative (SFARI) is funding 16 projects through its 2025 Data Analysis awards. This award is designed to encourage the use of large, publicly …
  33. Superconductor Theory Under Cold-Atom Scrutiny

    Physics
    Snapshot measurements of cold-atom gases reveal hidden spin correlations that could force an update of some superconductivity theories.
  34. Biogeochemical cycling of ubiquitous dissolved organic matter-derived polysaccharides in marine plankton

    Funded Work
  35. Assessing mRNA translation dysregulation in Gigyf1/2 mouse models of autism

    Funded Work
    Brain development and function require adaptive control of protein synthesis (mRNA translation), which is often disrupted in autism spectrum disorder (ASD).
  36. Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

    Funded Work
    Sleep disturbances are apparent in greater than 50 percent of autistic individuals.
  37. Scialog: Quantum Matter and Information

    Funded Work
    Research Corporation for Science Advancement (RCSA) RCSA is a private foundation that advances early-stage, high-potential, basic scientific research by providing catalytic funding for innovative research and …
  38. Featured Image: Disequilibrium on Display

    AAS Nova
    The Hubble Arp Galaxy Survey turned the talents of the Hubble Space Telescope toward 216 targets in the Arp and Arp–Madore catalogs. These catalogs contain galaxies that …
  39. Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

    April 15, 2026
    By tracking galaxy clusters hundreds of millions of light-years apart, researchers found the prevailing model of gravity still holds, reinforcing evidence for the existence of dark matter.
  40. Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

    April 15, 2026
    Analysis of a first-of-its-kind experiment reveals missing pieces in the decades-old theory of superconductivity.
  41. From SPARK to insight: visual data portals and AI multimodal foundation model integration of autism sequencing datasets

    Funded Work
    Autism research in genomics is hindered by fragmented data resources that are hard to combine in statistical models: while SFARI’s SPARK and Simons Simplex Collection cohorts provide …
  42. Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

    Funded Work
    Sleep disturbances are apparent in greater than 50 percent of autistic individuals.
  43. The ICM Comes to the United States, Philadelphia, July 23–30, 2026

    April 13, 2026
    … fortuitous. At the heart of the founding of the U.S. are ideals including acceptance, tolerance and openness. “We want to make the ICM as welcoming a …
  44. 2026 Targeted Grants to Institutes Announced

    April 10, 2026
    … Astrophysics Group at ICISE (SAGI), facilitating robust collaborative research in theoretical physics and astrophysics in Vietnam. Kavli Institute for Theoretical Physics (KITP) SFI will provide funding for …
  45. 2026 Simons Fellows in Mathematics Announced

    April 10, 2026
    … Florian Pop University of Pennsylvania Anantharam Raghuram Fordham University Emily Riehl Johns Hopkins University Arnd Scheel University of Minnesota Andreas Seeger University of Wisconsin–Madison Anne Shiu …
  46. AutismAtlas: Engineering serendipity in autism research by transforming data discovery and creating opportunities for data integration

    Funded Work
    The autism research landscape faces a critical data discovery bottleneck that fundamentally limits scientific progress.
  47. SHAReD - SFARI Heterogeneity in Autism — Reanalysis of data

    Funded Work
    Heterogeneity in autism is well documented and complicates efforts to identify biological and social mechanisms underlying the condition.
  48. Systematic analysis of the complete mutational spectrum of structural variation associated with autism and a continuum of developmental disorders from short-read and long-read genome sequencing

    Funded Work
    Autism is a phenotypically complex cluster of symptoms with genetic underpinnings that are governed by many common variants of subtle effect and a small number of rare, high …
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