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During early postnatal development, many neocortical brain areas exhibit “sensitive periods” where circuit refinement is driven by experience, by engaging both Hebbian (correlation-based) and homeostatic forms of … -
Challenges in social communication are one of the core symptoms of autism spectrum disorder (ASD).
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This project takes advantage of the rat as a model system to parse the role of striatal dopamine in social behaviors, specifically probing whether and how dysfunction in …
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Studies by two different research teams — one led by Ethan Greenblatt and the other by Emily Osterweil — both suggest that FXS cells under-synthesize large proteins, findings that … -
Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond. -
Funding student fellowships and programming at the Initiative for the Theoretical Sciences. The Initiative for the Theoretical Sciences at the CUNY Graduate Center endeavors to develop concise and … -
A new Astrophysics master’s program designed to prepare students from all backgrounds to excel in astronomy and physics doctoral programs as well as STEM careers. With the … -
To further our goal of funding the best and most transformative research on autism, SFARI strives to strike a balance between open requests for grant applications (RFAs) on … -
An annual, three-day meeting that encourages students to pursue advanced degrees in mathematics and mathematics education. The conference is geared toward undergraduates from Historically Black Colleges and … -
A program to help train the next generation of science, technology, engineering and mathematics leaders. With the Simons Foundation’s $56.6 million gift, the Stony Brook Simons … -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
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The National Institutes of Health (NIH) has recognized three outstanding current and former members of the Simons Collaboration on the Global Brain (SCGB) with the NIH Director’s … -
Alain Aspect, a Principal Investigator for the Simons Collaboration on Localization of Waves, received the 2022 Nobel Prize in physics along with John F. Clauser and Anton Zeilinger … -
Developmental biologist Jasmin Imran Alsous knows that it takes a village to raise an egg cell. At the Flatiron Institute, she and her collaborators are working together to … -
To advance our understanding of autism spectrum disorder (ASD) and to develop novel therapeutics, it is critical to understand how genetic and cellular changes lead to changes in …
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Guided by a long-held interest in brain function and behavior, Simons Junior Fellow Carla Golden is exploring the role that estrogen plays in the brain’s ability … -
Researchers at the Flatiron Institute and their colleagues trained a machine learning tool to capture the physics of electrons moving on a lattice using far fewer equations than … -
By examining the neuroinflammation and cognitive issues that can follow COVID infection in human studies and animal models, scientists are highlighting parallels to aging and neurodegenerative disease. -
Through the sequencing efforts of the Simons Simplex Collection (SSC), Simons Foundation Powering Autism Research (SPARK) and Autism Sequencing Consortium (ASC), thousands of de novo coding mutations have … -
… angle. Further data collected in the following months confirmed that the hypothesis supported in this work is indeed correct. Cantiello joined the foundation in 2017 as associate … -
Los Angeles-based organization combining innovation, transformation, and democratization to reimagine education and create systemic change. -
Organization amplifying youth and community power by inspiring, guiding and advocating for youth to determine their college, career and leadership futures. -
Education design company creating high-quality summer learning and out-of-school time opportunities for highly motivated yet historically excluded BIPOC students. -
Organization that aims to inspire and deepen the public’s ability to critically think about the social origins of global warming and environmental change. -
Recent advances in functional connectomics are shedding new light on circuit motifs in the worm, fly and mouse brains. -
Flatiron Institute’s Jennifer Cano is part of an international team that demonstrates a design principle for predicting whether metallic compounds are likely to host topological states caused … -
Novel tools for studying cnidarians’ distributed neural nets enable researchers to explore how neural ensembles form and interact. -
Flatiron applied mathematician Jason Kaye is bringing powerful new approaches to quantum physicists to help them answer big questions about small particles. -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
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The International Conference on Recent Progress in Many-Body Theories has awarded the Hermann Kümmel Early Achievement Award in Many-Body Physics to quantum physicist Aavishkar Patel. The … -
Antoine Georges, the director of the Flatiron Institute’s Center for Computational Quantum Physics (CCQ), received the Feenberg Memorial Medal on September 14 at the International Conference Series … -
… Zhang Columbia University -
Our new Science Sandbox Spotlight series aims to highlight the people behind the organizations in our grantee portfolio. In the series’ first installment, we speak with Ran Yan … -
… approaches on a problem of high agricultural significance. -
SFARI is pleased to announce that it intends to fund 16 grants in response to the 2022 Pilot Award request for applications. -
Is there another Earth out there? Flatiron Institute astronomer Megan Bedell is on the hunt for Earth 2.0. And she’s making new discoveries about sunlike stars … -
Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.
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… cognitive function even late in life — a phenomenon known as cognitive resilience. While the causes of age-related cognitive degeneration are largely unknown, heritability estimates indicate a … -
The Simons Foundation, the Alfred P. Sloan Foundation, the Gordon and Betty Moore Foundation and the John Templeton Foundation are inviting applications to a one-time call aimed … -
How does sleep sustain synaptic lipid function across life? -
SFARI hosted a virtual workshop on March 14 and 18, 2022, to discuss the best practices for the development and use of induced pluripotent stem (iPS) cell models … -
New zebrafish lines with mutations in the high-confidence autism risk genes DYRK1A and GRIN2B have been added to SFARI resources. -
Simons Junior Fellow Tim Large studies the mathematics underlying the spaces that control planetary orbits and the physical laws of motion. -
The world’s population is rapidly aging. -
Phenotypic data from 296,307 participants enrolled in SPARK, including 117,203 individuals with ASD, are now available to approved researchers. Genomic data (whole-exome sequencing and genome … -
Clinical Research Associates, L.L.C., an affiliate of the Simons Foundation, has recently launched a randomized controlled trial to test the safety, tolerability and efficacy of arbaclofen …