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August 18, 2022In a series of articles published in the journal Nature Genetics, researchers used data from the SPARK research cohort, which was created to advance our understanding of the … -
August 16, 2022Gina Turrigiano and colleagues showed that the phosphorylation state of the autism-associated synaptic scaffold protein Shank3 can bias synapses toward upward or downward homeostatic plasticity.
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August 16, 2022Vinod Menon and colleagues showed that a subregion of the auditory cortex decodes emotional cues in a communication partner’s voice and that this predicts social communication abilities …
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Funded WorkSleep problems occur at a higher rate in people with autism spectrum disorder (ASD), affecting up to 93 percent of people with ASD. -
Funded WorkIt is unknown how the COVID-19 pandemic affects pregnant women and their offspring. -
August 9, 2022At the Flatiron Institute, Christopher Park studies how mutations in RNA might play a role in neuropsychiatric conditions like autism, schizophrenia and ADHD. -
August 8, 2022Suzanne Staggs, a physicist at Princeton University and founding member of the Simons Observatory, describes what cosmic microwave background (CMB) radiation can reveal about the early universe. -
August 4, 2022… galaxies’ evolution and create predictions for future observations. “One thing we still don’t really understand is how they formed so quickly,” says Yung. “They’re only … -
Funded WorkReciprocal cooperation is a hallmark of social groups and is central to successful social interaction, playing a major role in evolutionarily shaping brain functions and enabling rich social … -
Funded WorkAltered sensory processing is a core and predictive feature of autism spectrum disorder (ASD). -
Funded WorkIndividuals with autism spectrum disorder (ASD) perceive and experience the world differently than neurotypical individuals. -
Funded WorkLike many complexly inherited conditions, autism shows high heritability, yet the inventory of identified genomic variants appears to explain only a modest portion of the risk. -
August 3, 2022Physicists at the Flatiron Institute’s Center for Computational Quantum Physics and their collaborators have created a new way to simulate quantum entanglement between interacting particles. Their approach … -
August 2, 2022Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond. -
Funded WorkAutism spectrum disorder (ASD) results from alterations in the development of neural circuits in the brain and leads to a variety of clinical conditions, including insistence on sameness … -
Funded WorkGRIN disorders are rare genetic conditions that affect one of the seven GRIN genes that encode NMDA receptor subunits, which mediate excitatory synaptic transmission in the brain. -
Funded WorkLanguage difficulties and intellectual disability affect approximately one-third of individuals with autism spectrum disorder (ASD) and predict quality of life for adults with ASD. -
Funded WorkDetermining genotype-phenotype relationships for gene variants that increase susceptibility to autism spectrum disorder (ASD) is critical for understanding underlying mechanisms and identifying therapeutic targets. -
Funded WorkFood and Drug Administration (FDA) approval and clinical use of antisense oligonucleotide (ASO) therapies have demonstrated their potential for treating monogenic disorders. -
Funded WorkAutism spectrum disorder (ASD) represents a group of hundreds of individually rare conditions which are in large measure due to mutations in genes produced in the brain. -
August 1, 2022Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
July 28, 2022Joshua K. Hartshorne, Stefano Anzellotti and colleagues used machine learning to disentangle variations in neuroanatomy that are specific to autism from variations common to the general population.
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July 27, 2022SFARI is pleased to announce that it has selected seven fellows in response to the 2022 Bridge to Independence Award request for applications. -
July 27, 2022Catherine Dulac and her collaborators identified a population of cells in the hypothalamus that generate fever and influence the activity of brain areas associated with behavior during sickness … -
July 27, 2022New phenotypic data from Simons Searchlight participants were recently added to SFARI Base. This release includes data from individuals with 59 gene changes and nine copy number variants … -
July 26, 2022Center for Computational Quantum Physics research fellow John Bonini is developing tools to elucidate quantum systems. -
July 25, 2022Theater of the Mind, an immersive experience that journeys “inside the human brain,” will soon premiere in Denver. -
July 25, 2022After uncovering new insights into how HIV hijacks the body’s innate immune system, Simons Junior Fellow Benem-Orom Davids is now exploring a possible viral component of … -
July 20, 2022By subjecting a quantum computer’s qubits to quasi-rhythmic laser pulses based on the Fibonacci sequence, physicists demonstrated a way of storing quantum information that is less … -
July 19, 2022Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond. -
July 18, 2022As we age, our brains and bodies accumulate cells that have stopped dividing. Early studies in mice suggest that eliminating those cells might improve age-related memory loss … -
July 18, 2022Dr. Whitney Gaskins grew up in predominantly Black churches. Now she’s connecting these communities with STEM engagement opportunities. -
July 15, 2022Three talented early-career scientists in systems and computational neuroscience have been selected as the first Simons Collaboration on Plasticity and the Aging Brain Transition to Independence fellows … -
July 15, 2022… behaviors. Ran is a postdoctoral fellow at Harvard Medical School. His research will further investigate how visceral organs are represented throughout the brain, and how viscerosensory codes … -
July 11, 2022Data visualization engineer Elizabeth Lovero combines her passions for art and computer programing to help scientists make new discoveries.
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July 8, 2022Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
July 8, 2022A recent wave of research is using pharmacology to test new hypotheses of neural coding and cognition. -
SeriesThe International Congress of Mathematicians 2022 (ICM 2022) took place virtually from July 6–14, 2022. These award videos premiered at the 2022 International Congress of Mathematicians in … -
July 5, 2022Through mathematically accurate animation and model-building — freely available for others around the world to use — Nikolai Andreev of the Steklov Mathematical Institute of the Russian Academy of … -
July 5, 2022For seven decades, Elliott H. Lieb of Princeton University has made deep mathematical contributions that have shaped the fields of quantum mechanics, statistical mechanics, computational chemistry and quantum … -
July 5, 2022Barry Mazur of Harvard University made profound discoveries in topology, arithmetic geometry and number theory and is also known for his leadership and generosity in developing the next … -
July 5, 2022Mark Braverman of Princeton University made breakthroughs in the theory of information complexity, enabling the development of ingenious compression methods and noise-resilient communication protocols. -
July 5, 2022… Russian mathematician and recognizes revolutionary results in or with applications to mathematical physics. Jitomirskaya received the prize for her “groundbreaking work in mathematical physics, especially on the … -
July 5, 2022Maryna Viazovska of the École Polytechnique Fédérale de Lausanne (EPFL) proved that the E8 lattice provides the densest packing of identical spheres in eight dimensions while also solving … -
July 5, 2022James Maynard of the University of Oxford made major advances in number theory — in particular, the location of prime numbers and the approximation of real numbers with fractions. -
July 5, 2022June Huh of Princeton University studied abstract spaces built from combinatorial objects, enabling him to make many breakthroughs, including the proof of the Dowling–Wilson conjecture for geometric … -
July 5, 2022Hugo Duminil-Copin of the University of Geneva and the Institut des Hautes Études Scientifiques (IHES) solved longstanding problems in the probabilistic theory of phase transitions in statistical … -
July 5, 2022The first ever OAL Prize, celebrating the life of the noted Russian mathematician, honors outstanding contributions to the mathematics underlying previously unsolved problems in quantum physics.