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Autism BrainNet is working to digitize the Autism Celloidin Library, a unique collection of 28 celloidin-embedded, Nissl-stained brains from donors with and without autism spectrum disorder …

… points. First, they needed to generate such data—and advances in automated systems, such as liquid handling and DNA sequencing, brought forth the desired deluge of information …

A new tool aligns research efforts in the aging brain in six different species.

Three SFARI Investigators (current and past) have recently received prestigious prizes in the natural sciences.

SFARI is pleased to announce that it intends to fund 17 grants in response to the 2021 Genomics of ASD: Pathways to Genetic Therapies request for applications.

Lilia Iakoucheva and colleagues found that mice lacking a copy of the high-confidence ASD risk gene Cul3 have reduced brain volumes, potentially due to defects in Rho …

Melissa Gymrek and colleagues developed a framework for the identification and prioritization of de novo mutations at tandem repeats on a genome-wide scale and assessed their contribution …

How a retrofitted old transit bus turned into a fleet of science vehicles engaging students

‘Geometric frustration’ can cause the electrons in materials with atoms arranged in a triangular pattern to organize in three competing ways simultaneously, reveals a new computational study …

Check out these presentations from SCGB PIs and trainees at the virtual SFN conference November 8-11.

… best wishes via prerecorded video message, lauding Spergel’s work in encouraging — and guiding — government funding of science. The celebrations focused not only on Spergel but also …

A number of presentations will be given by SFARI Investigators at Neuroscience 2021 (November 8–11).

… celebrate his inauguration. Simons Foundation president David Spergel and guests celebrate his inauguration. Simons Foundation president David Spergel and guests celebrate his inauguration. Simons Foundation president David …

Our gut is tasked with a unique challenge: to maintain tolerance of food and healthy microbes, while protecting the body from invading pathogens. A delicate balance between neurons …

Three SFARI Investigators (current and past) are among this year’s 100 newly elected members of the National Academy of Medicine.

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.

The AbacusSummit simulations will help scientists extract information about the universe from upcoming cosmological surveys.

The American Physical Society has named Blakesley Burkhart the winner of the 2022 Maria Goeppert Mayer Award, which recognizes and enhances outstanding achievement by a woman physicist in …

The National Institutes of Health (NIH) has recognized four outstanding neuroscientists supported by the Simons Foundation. Coleen Murphy, director of the Simons Collaboration on Plasticity and the Aging …

The grants bring to the collaboration new investigators studying how populations of neurons in different parts of the brain communicate.

By stitching together an unprecedented diversity of data, a new software platform has enabled scientists to robustly predict what proteins do.

Bilal Haider and colleagues found that Cntnap2 knockout mice exhibited deficits in visual perception and that these were associated with diminished excitation and elevated inhibition in the visual …

Jun Huh and colleagues found that maternal immune responses to infection may at least partially explain sex-specific differences in autism risk.

… people show symptoms of COVID-19. ‍ Investing in the future If sequencing technology prepared us for the COVID-19 pandemic, that’s only because of the decades …

SFARI is pleased to announce that it intends to award 11 grants in response to the 2021 Human Cognitive and Behavioral Science request for applications.

Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.

Researchers are pivoting in clever ways, but they worry that the lack of spontaneous interactions is harming the next generation.

A recent study has uncovered new ASD inherited genetic risk variants. Over of the 50 percent of the genetic data used in the study came from SPARK.

Michael Platt and colleagues found that monkeys create complex internal representations of social situations and uncovered neural circuitry supporting social cooperation.

SFARI consultant-in-residence Gaspar Taroncher-Oldenburg discusses his work and collaboration with the Simons Foundation Flatiron Institute to study the microbiome and its potential implications for ASD …

A number of SFARI Investigators, collaborators and Simons Foundation scientists will present their latest research findings at the American Society of Human Genetics (ASHG) 2021 Virtual Meeting, which …

For more than 2,000 years, number theorists have been trying to understand the properties of solutions to polynomial equations. In his research, Simons Junior Fellow Michele Fornea …

SFARI held a virtual version of its spring science meeting in a series of four webinars in April and May 2021. The webinars were organized around themes of …

The Blavatnik Family Foundation and the New York Academy of Sciences have named computational chemist Erik Thiede as a finalist for the 2021 Blavatnik Regional Award for Young …

Zebrafish lines for autism risk genes DYNC1H1 and MEF2C have been recently added to SFARI resources to study autism spectrum disorder.

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

Longitudinal studies of the oldest old could reveal how some people’s brains resist the ravages of time.

In an effort to enhance diversity in neuroscience, a new program from the Simons Collaboration on the Global Brain (SCGB) pairs undergrads with research mentors.

Simons Junior Fellow and computational neuroscientist Kathryn Bonnen uses advanced modeling and experimental techniques to help us understand what happens inside our minds as we perceive the world …

On June 25 and 28, 2021, SFARI hosted a workshop to discuss sleep challenges in autism and learn more about ways to improve sleep quality in individuals with …

J. Elliott Robinson talks about his lab’s work on the neural circuits involved in neurofibromatosis type 1 and developing gene therapy treatments for the condition, and how …

Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.

Stelios Smirnakis and Huda Zoghbi observed an increase in the formation and stabilization of dendritic spine clusters in the cortex of MECP2 duplication syndrome mice.

Evan Eichler and colleagues used targeted sequencing in large neurodevelopmental cohorts, including SPARK, to identify new risk genes and relate genotype to phenotypic presentation.

Pawan Sinha and colleagues found that sensory habituation is reduced in autism, and furthermore, that this reduction correlates with behavioral assessments of social communication and sensory difficulties.

SFARI is pleased to announce that it intends to fund four grants in response to the Maternal COVID-19 as a Potential Risk for Autism: Supplemental Funding for …

With standardized datasets, community-building challenges and simplified software bundles, research initiatives strive to bring uniformity to analysis in neuroscience.