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Bringing people and ideas together to fund, conduct, and share transformative science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Mathematicians Unleash Multifold Speed Boost for Supercomputer Simulations of Molecules

    June 24, 2026
    By leveraging a classical mathematical function in simulations of molecular behavior, researchers at the Simons Foundation’s Flatiron Institute drastically sped up the simulations while maintaining the same …
  2. 2025 Letter From the Chair

    June 23, 2026
    Simons Foundation Chair Marilyn Simons reflects on the two-way street between math and science, the power of collaboration and how sharing ideas across fields drives unexpected discoveries.
  3. Mathematicians and String Theorists Push Each Other’s Fields Forward

    June 23, 2026
    … interesting, and it helps bring more people from one community to the other. It’s a scenario where one plus one is actually bigger than two.”
  4. The Mathematical Tools Trailblazing the Quantum Future

    June 23, 2026
    … benchmark their quantum claims. Researchers at the CCQ are continually working to improve their tensor network libraries to better handle complex systems and incorporate new techniques under …
  5. Delving Into the Mathematical Absurdities of Black Holes

    June 23, 2026
    … For Isi, the many unanswered questions about black hole observations only add to the excitement, “because it’s such a clear indication that there’s much yet …
  6. Building an AI That Understands the Universe

    June 23, 2026
    … a single DNA mutation could have ripple effects throughout the body) remains out of reach for many models. The first iteration of the Polymathic AI model can …
  7. Beyond the Cryo-EM Resolution Revolution

    June 23, 2026
    … cryo-EM data. To create the most useful tools, Flatiron researchers brought together an interdisciplinary cohort of investigators to provide input. Cossio and computational biophysicist Sonya Hanson …
  8. Pivot Fellow Natasha Blitvic Brings Math to Marine Microbiology

    June 23, 2026
    Mathematician Natasha Blitvic brought her expertise in probability to the complex world of marine microbes, using a Simons Foundation Pivot Fellowship to explore how randomness at microscopic scales …
  9. Why We Need Computation To Understand the Brain

    June 23, 2026
    … postdoctoral fellows and those transitioning to academic independence. Laura Driscoll, now a scientist at the Allen Institute for Neural Dynamics, received one of those fellowships to support …
  10. How Mathematical Modeling Identified Subclasses of Autism

    June 23, 2026
    … work.”
  11. Quanta Books Opens a New Chapter in Science Publishing

    June 23, 2026
    … physicist David Tong, on quantum field theory. Lin teases that future years’ book slates include titles on astronomy, geology and biology. “You hear a lot of people …
  12. Pi Day Festivities Highlight the Beauty in Mathematics

    June 23, 2026
    … human experience or connecting artists with scientists to create pieces centered on the theme of symmetry, there will be plenty to explore. “Math education is often focused …
  13. First Simons Postdoctoral Fellows in Plant Biology Announced

    June 23, 2026
    The program provides funding for early-career researchers who are interested in a career in plant biology.
  14. SFARI Sex Differences Collaborations Convene for Fourth Annual Meeting

    June 18, 2026
    … reported that measures of gene expression and chromatin accessibility across the genome followed patterns specific to the XX or XY status of an individual cell, regardless of …
  15. Remembering Physicist and Emeritus Trustee Peter Littlewood

    June 18, 2026
    The distinguished theoretical physicist, scientific leader and long-serving board member passed away on June 15, 2026.
  16. The Science of Team Science: Lessons Learned From the International Brain Laboratory

    June 16, 2026
    The International Brain Laboratory, a consortium of 22 labs worldwide working together to study decision-making in the brain, offers insights into how large-scale scientific collaborations can …
  17. Axel Saenz Rodriguez on How Mathematics Can Create More Sustainable Energy

    June 16, 2026
    Pivot Fellow Axel Saenz Rodriguez leverages mathematics and quantum physics to create energy efficient strategies for storing and transmitting data.
  18. SFARI Hosts 2026 Investigator Meeting

    June 15, 2026
    The Simons Foundation Autism Research Initiative held its annual investigator meeting on March 16–18, 2026, in New York City.
  19. SFARI To Fund Patient Advocacy Group Conferences and Travel Awards for Scientists

    June 15, 2026
    SFARI plans to support 17 meetings organized by patient advocacy groups within the Simons Searchlight community.
  20. Acetylcholine Helps Dopamine Reward Hard Work

    June 11, 2026
    … 6852 (2023) PubMed Liu C. et al. Science 375, 1378–1385 (2022) PubMed Krok A.C. et al. Nature 621, 543–549 (2023) PubMed Chantranupong L. et …
  21. Watch: A Short Film on the Art of Discovery and How Ideas Are Shaped

    June 10, 2026
    Filmmaker Elsa Wong and physicist Marc Ritter collaborated to create MOSS, a film exploring the similarities between scientific inquiry and artistic creation.
  22. Kelsey Martin Wins Kavli Prize in Neuroscience

    June 10, 2026
    The prize recognizes Martin’s contributions to the discovery of local protein translation in neurons.
  23. Quanta Books Releases The Proof in the Code

    June 9, 2026
    The book, written by journalist Kevin Hartnett, tells the story of the birth and rise of Lean, a proof assistant that’s ushering in the biggest modern shift …
  24. How an Autism-Associated Gene Keeps Synapses Stable

    June 9, 2026
    Epilepsy and intellectual disability often occur alongside autism spectrum disorder (ASD), and researchers have long suspected that these conditions share common biological roots.
  25. CCN Researcher SueYeon Chung Named McKnight Scholar

    June 8, 2026
    … joining the Flatiron Institute, Chung was a postdoctoral research scientist at Columbia University’s Center for Theoretical Neuroscience. Before that, she was a fellow in computation in …
  26. Travel Grants Help Hundreds of Mathematicians Attend ICM 2026

    June 8, 2026
    The Simons Foundation is helping scientists from developing countries travel to the meeting, widely regarded as the most significant gathering in mathematics.
  27. Watch: Concrete Cosmos, a Short Film on the Shared Frequencies of the Universe and the Human Experience

    June 3, 2026
    Flatiron Research Fellow Adrian Bayer and filmmaker Adonis Williams teamed up to explore the connections between cosmic structures and day-to-day life.
  28. Media Invitation: Fields Medals and Cutting-Edge Math at ICM 2026 in Philadelphia

    June 2, 2026
    … Society and the Simons Foundation, and marks the first ICM in the United States since 1986. Thousands of mathematicians will attend the event, with hundreds from developing …
  29. Coming Soon: Open Interval, an Artist-Scientist Exploration of ‘Turbulence’

    June 1, 2026
    The next Open Interval program will enable trios of artists, scientists and arts organizations to collaborate deeply for several months on the science and art of “turbulence.”
  30. Funding Available for Synthetic Plant Biology Research

    June 1, 2026
    The funding will support research aimed at advancing our understanding of how plants function.
  31. Turbulence: A Nexus of Creative Possibilities

    June 1, 2026
    “Turbulence” will be the theme of the next Open Interval program, which supports trios of artists, scientists and arts organizations ready to think outside their disciplines.
  32. A Liver Enzyme Produced During Exercise Might Reverse Memory Loss

    May 28, 2026
    In a new study by scientists with the Simons Collaboration on Plasticity and the Aging Brain, an enzyme produced in the liver during exercise helped repair brain blood …
  33. Watch: An Experiential Documentary on the Power of Translation

    May 27, 2026
    A collaboration between Flatiron Institute Research Fellow Lukas Devos and filmmaker Danya Abt explores how we shape meaning.
  34. Protein Levels, Not Just Transcripts, Hold Clues to Autism

    May 26, 2026
    … forming connections with other neurons, making it genetically vulnerable. The same research team had previously identified this window as a time of heightened autism risk using an …
  35. Black Hole Discoveries Abound in Newly Released LIGO-Virgo Catalog

    May 26, 2026
    Observations of colliding black holes from the LIGO-Virgo-KAGRA collaboration are shedding new light on the universe’s darkest inhabitants as well as on the nature of …
  36. Watch: A Short Film About a Scientist and a Microscopic Being

    May 20, 2026
    Flatiron Institute computational biologist Sonya Hanson and filmmaker Diego Murillo collaborated on a short film that examines the strange resilience of the tardigrade.
  37. Hidden Patterns: Kevin Hu Navigates the Mathematics of Disordered Systems

    May 19, 2026
    Simons Society of Fellows Junior Fellow Kevin Hu explains how coin flips and balls rolling downhill relate to complex problems in probability and mathematical physics.
  38. Alumni Spotlight: Gokberk Kabacaoglu

    May 15, 2026
    Kabacaoglu, a former research fellow at the Simons Foundation’s Flatiron Institute, is now an assistant professor in the Department of Computer Science at Durham University in England …
  39. Now Accepting Applications for Workshops on Quantitative Behavioral Phenotyping in Autism

    May 14, 2026
    The Simons Foundation Autism Research Initiative will hold three workshops aimed at developing a multiyear collaborative effort in quantitative behavioral analysis of individuals with autism.
  40. Alumni Spotlight: Christopher Lam

    May 13, 2026
    A former Flatiron Institute pre-doctoral fellow, Lam now works on the Nancy Grace Roman Space Telescope.
  41. Watch: A Short Film on the Secret Life of Electrons and the Power of a Collective

    May 13, 2026
    Flatiron Associate Research Scientist Olivier Gingras and filmmaker Yan Shao collaborated on a film exploring the transition of a single electron to the collective state of superconductivity.
  42. Seeing and Imagining Are Handled by the Same Brain Cells

    May 12, 2026
    Researchers make advances in understanding how human brains are wired by pinning down how the same neurons are used for both imagining and seeing objects.
  43. Unbiased Approaches to Quantifying Motor and Other Visible Behaviors in Humans With Autism

    May 11, 2026
    On January 22–23, 2026, SFARI held a workshop to explore advanced quantitative phenotyping methods for capturing visible behaviors, including motor phenotypes.
  44. Alumni Spotlight: Ryan Levy

    May 8, 2026
    A former Flatiron Institute research fellow, Levy now explores how fault-tolerant quantum computers can advance basic research.
  45. Watch: 5 Math-Inspired Short Films Created by Flatiron Institute Researchers and Filmmakers

    May 6, 2026
    As part of the Simons Foundation’s Infinite Sums initiative, the 2026 Symbiosis program produced five experimental short films rooted in mathematics.
  46. Alumni Spotlight: Jamie Morton

    May 6, 2026
    Collaborations during Morton’s time as an associate research scientist at the Simons Foundation’s Flatiron Institute inspired his new startup.
  47. AI Will Be Top of Mind at ICM, Math’s Biggest Conference

    May 4, 2026
    The International Congress of Mathematicians, coming to Philadelphia this summer, includes panels and talks about artificial intelligence and the humanity of the field.
  48. Applications for 2027 Simons Graduate Fellowships in Ecology and Evolution Now Open

    May 1, 2026
    The Simons Foundation’s Life Sciences division is now accepting applications for its 2027 Simons Graduate Fellowships in Ecology and Evolution. The application deadline is June 30, 2026 …
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