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SFARI is pleased to announce that it intends to fund eight grants in response to the 2020 Research Award request for applications. -
Astrophysicist Brian Metzger has been named the 2020 Blavatnik National Awards Laureate in Physical Sciences & Engineering by the Blavatnik Family Foundation. The honor recognizes Metzger’s contributions to … -
Strange metals have surprising connections to high-temperature superconductors and black holes. -
Observations by the Atacama Cosmology Telescope suggest that the universe is 13.8 billion years old. -
SFARI would like to remind researchers that they can still request many SFARI resources, including genetic and phenotypic data as well as biospecimens, at this time. Researchers can … -
Neuroscientists are uncovering patterns of neuron population activity during different movements and in new places, but why these dynamics exist is still a mystery -
Machine-learning methods can predict the long-term stability of planetary configurations 100,000 times faster than previous approaches. -
… something similar about the fiery bodies racing across the sky until some bold thinkers cracked the patterns. As a reproducible and evolvable system subject to cutting-edge … -
Why do some stellar explosions produce elements like gold but others do not? Through machine-learning techniques, Ashley Villar of the Simons Society of Fellows hopes to glean … -
SFARI Investigators will be giving a number of presentations as part of the 12th FENS Forum of Neuroscience. Due to the COVID-19 pandemic, the forum will be … -
Rice University’s Michael Wolf not only explores Riemann surfaces and other math problems, but he also prepares students from underprivileged backgrounds for a future in science and … -
The International Society for Autism Research (INSAR) 2020 Annual Meeting to be held May 2020 was canceled, but virtual content is now available online. A selection of abstracts … -
This video series documents the building of the Simons Observatory, which will look for signs of cosmic inflation to answer questions about the origin of the universe. -
Neurons that regularly remodel are more prone to the dysfunctions linked to the disease’s onset, a new experimental and computational study finds. -
By studying neural activity, Marlene Cohen has found that attention alters how neurons carry information. -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
On February 6–7, 2020, SFARI convened a two-day workshop to explore the possibility of gene therapies for autism spectrum disorder. -
Model builders once had to fumble in the dark to find the parameters that made their models work. Software called SNPE and EPI now enables the full parameter … -
We can easily distinguish small quantities, but we utterly fail when numbers get big. Pooja Viswanathan of the Simons Society of Fellows has uncovered the neurons underlying this … -
This year, Juneteenth will be a day off for staff at the Simons Foundation. As we have seen from the horrific violence against black men and women in … -
… role of theory in cryptography, algorithmic economics, privacy, quantum information, computational biology, social sciences and more. The project will form and study basic frameworks that address discrimination … -
… new devices and breakthrough technology. -
Intense radio emissions produced by the fast-spinning stars are caused by newborn particles interacting with powerful electromagnetic fields, new plasma simulations suggest. -
Gina Turrigiano and colleagues showed that loss of Shank3 disrupts homeostatic plasticity and that this deficit can be rescued by the mood-stabilizing drug lithium (Li+). -
A SFARI Investigator and a past member of SFARI’s Scientific Advisory Board are among the 146 newly elected members of the National Academy of Sciences. -
Two quantum particles can be intimately connected even when they are far apart, forming patterns beyond the scope of classical physics. When vast numbers of them link up … -
The director of the Institute for Advanced Study discusses how artistic talent and synesthesia informed his approach to physics research and why progress depends on bridging the communications … -
Three current and former SFARI Investigators and one member of SFARI’s Scientific Advisory Board are among the 276 newly elected members of the American Academy of Arts … -
Leveraging personalized genomics can aid the development of effective autism therapies, promising new research suggests. -
Originally scheduled for an August 2020 premiere in Denver, the immersive installation is a journey inside the human brain. -
As we think, information is routed all over the brain, undergoing a complex series of transformations. Successful tracking of those transformations may help scientists decipher the brain’s … -
How we facilitate the formation of a cohesive community that transcends race, gender and geographic boundaries in just three weeks. -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
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Alex Kwan and colleagues used in vivo calcium imaging to show that a mutation in Shank3 associated with schizophrenia affects the activity of inhibitory neurons in the cortex … -
New data were added to SFARI Gene in April 2020. This data release included the addition of new candidate autism risk genes, new curated references of copy number … -
Physicists propose that the influence of cosmic rays on early life may explain nature’s preference for a uniform “handedness” among biology’s critical molecules. -
Phenotypic data from 230,936 participants enrolled in SPARK, including more than 90,000 individuals with ASD, are now available to approved researchers. -
AI can recognize faces, drive cars and simulate the universe, but precisely how it works remains unknown. Flatiron Institute scientists plan to solve the mystery. -
The European Academy of Sciences has elected Angel Rubio as a fellow of its materials science division in recognition of his scientific achievements. Rubio is a distinguished research … -
Artificial intelligence techniques accurately calculate the energy required to make — or break — simple molecules. -
Catharine Rankin, Kurt Haas, Paul Pavlidis and colleagues used machine vision to find that mutations linked to ASD risk genes are associated with changes in habituation of response … -
David Sulzer and colleagues used conditional knockout mice of Atg7, a protein involved in autophagy, to study the effects of loss of autophagy on the structure and function … -
BERNARD RIEMANN was not even 40 years old when he died, but in his short life, he made an indelible imprint on vast swaths of mathematics. Riemann sums … -
The 160-year-old Riemann hypothesis has deep connections to the distribution of prime numbers and remains one of the most important unsolved problems in mathematics. -
David Hilbert put forth 23 problems that helped set the research agenda for mathematics in the 20th century. Here is a status report on those challenges. -
Genetic Mutations Linked to Kleefstra Syndrome Converge on Similar Neuronal Hyperactivity Phenotypes
Nael Nadif Kasri and colleagues used micro-electrode array assays to demonstrate common neuronal network phenotypes associated with genes underlying Kleefstra spectrum syndrome. -
… Investigator, Simons Collaboration on Principles of Microbial Ecosystems. Jacob Lurie Institute for Advanced Study. 2018 Simons Fellow in Mathematics. Gregory Moore Rutgers, the State University of New … -
Genetic dark matter makes up 98 percent of our genomes, yet scientists are still figuring out how it works.