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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

Our grants advance knowledge and strengthen connections between science and society.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Nevanlinna Prize Video: Constantinos Daskalakis

    August 1, 2018
    Constantinos Daskalakis of M.I.T. transformed the understanding of computational complexity in markets, auctions and other economic structures. His work provides algorithms and defines limits on what …
  2. Foundation Announces Simons Collaboration on Localization of Waves

    July 24, 2018
    The Simons Foundation is pleased to announce the establishment of the Simons Collaboration on Localization of Waves, directed by Svitlana Mayboroda of University of Minnesota. Waves of all …
  3. Foundation Announces Simons Collaboration on Hidden Symmetries and Fusion Energy

    July 24, 2018
    … physics, dynamical systems and the analysis of partial differential equations. This collaboration has, therefore, assembled a multidisciplinary team of world experts in these disciplines, reflecting the breadth …
  4. SFARI RFA Reboot: Why, What and How

    July 16, 2018
    In this blog post, the SFARI science team provides insight into why SFARI’s request for applications grant programs are being revamped, which award types are being changed …
  5. Quanta Magazine Celebrates Five Years of Public Service Science Journalism

    July 16, 2018
    The award-winning magazine is illuminating fundamental math and science research for millions of readers around the world
  6. AI Accurately Predicts Effects of Genetic Mutations in Biological Dark Matter

    July 16, 2018
    The new deep learning technique could help researchers identify the genetic origin of diseases and better understand how evolution shaped our genes
  7. Workshop Highlights Online Platforms for Visualizing and Exploring SFARI Genomics Data

    July 16, 2018
    On April 10, 2018, SFARI held a workshop to discuss online platforms for visualizing and analyzing SFARI genomics data. These platforms included the Genotypes and Phenotypes in Families …
  8. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    July 12, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  9. Drosophila and Zebrafish Models Added to SFARI Gene

    July 9, 2018
    The animal models module of SFARI Gene has recently been expanded to include two new species: Drosophila melanogaster and Danio rerio. As of now, the database lists 55 …
  10. FENS Forum 2018: Presentations by SFARI Investigators

    July 6, 2018
    SFARI Investigators will be giving a number of presentations at the 11th FENS Forum of Neuroscience in Berlin, Germany (July 7-11).
  11. The Gaia Sausage: The Major Collision That Changed the Milky Way Galaxy

    July 4, 2018
    … Astronomy, University of Cambridge, U.K. ([email protected]) Sergey Koposov, Department of Physics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA ([email protected]) Alis Deason, Department …
  12. Schooling Fish May Offer Insights Into Networked Neurons

    June 19, 2018
    Iain Couzin is deciphering the rules that govern group behavior. The results might provide a fresh perspective on how networks of neurons work together.
  13. Controlling the Brain With Holograms

    June 14, 2018
    New technology allows neuroscientists to modify neural activity with unprecedented spatial and temporal precision.
  14. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    June 12, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  15. How Fruit Flies Woo a Mate

    May 30, 2018
    Male flies watch females carefully but choose their particular moves according to their mood.
  16. Flatiron Hosts First MountainSort Users Workshop

    May 24, 2018
    On May 17, 2018, nineteen users of our spike-sorting software package gathered at CCB from eight different neuroscience laboratories from across the US and UK. We discussed …
  17. NSF-Simons Centers To Search for the Rules of Life

    May 24, 2018
    The new centers bridge biology and mathematics to uncover how genetic codes spawn complex life
  18. Imitate Your Way to the Top

    May 16, 2018
    Using examples and hints, a new algorithm provides a simple and efficient method for constructing models of neural circuits.
  19. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    May 9, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  20. SFARI Investigators Elected to the National Academy of Sciences

    May 7, 2018
    Two SFARI Investigators are among the 84 newly elected members of the National Academy of Sciences.
  21. 2018 Simons Early Career Investigators in Marine Microbial Ecology and Evolution Announced

    May 7, 2018
    The Simons Foundation has named four scientists as 2018 Simons Early Career Investigators in Marine Microbial Ecology and Evolution. The three-year awards are intended to help launch …
  22. National Academy of Sciences Elects 10 Simons Investigators and Fellows in 2018

    May 4, 2018
    … Collaboration on the Many Electron Problem and a consultant for the Center for Computational Quantum Physics at the Flatiron Institute. Christopher Walsh is chief of the genetics …
  23. Finding Neural Patterns in the Din

    May 4, 2018
    A new algorithm, called seqNMF, can detect sequences in neural data generated by ‘internal behaviors,’ such as an animal thinking or sleeping.
  24. SFARI Presentations at INSAR 2018

    May 3, 2018
    SFARI Investigators and SFARI science staff will be giving a number of oral presentations at the International Society for Autism Research (INSAR) 2018 Annual Meeting in Rotterdam, Netherlands …
  25. SFARI Posters at INSAR 2018

    May 3, 2018
    SFARI science staff will be presenting a number of posters about SFARI projects and resources at the International Society for Autism Research (INSAR) 2018 Annual Meeting in Rotterdam …
  26. SFARI Survey: Request for Feedback About iPS Cell Models of Autism

    May 3, 2018
    SFARI is soliciting your feedback about the utility and priority of induced pluripotent (iPS) cells from individuals with high-confidence autism risk variants. Your comments will help us …
  27. Simple Networks Generate Complex Dynamics

    May 3, 2018
    Elegant new research predicts how minor changes in connectivity can drive major changes in how a circuit behaves.
  28. SFARI Investigators Elected to the American Academy of Arts and Sciences

    May 2, 2018
    Six current and former SFARI Investigators are among the 213 newly elected members of the American Academy of Arts & Sciences, one of the nation’s oldest and most …
  29. Upcoming Changes to SFARI’s Requests for Grant Applications

    May 2, 2018
    SFARI’s requests for grant applications will be undergoing a number of changes in the coming months. These changes include ending the Explorer Award program, updating the Pilot …
  30. SFARI Gene: New Data Release

    May 1, 2018
    New data were added to SFARI Gene in April 2018. This data release included updated gene scores for candidate autism risk genes, as well as the addition of …
  31. The Eternal Sky, Part 3: Tools for Bang or Bounce

    May 1, 2018
    Telescopes at the Simons Observatory will help decipher the origins of the universe. Third in a series.
  32. Assembly of Massive Galaxy Cluster Witnessed for the First Time

    April 25, 2018
    A dense flock of 14 galaxies from 1.4 billion years after the Big Bang is destined to become one of the most massive structures in the modern …
  33. American Academy of Arts and Sciences Elects Simons Grantees

    April 24, 2018
    Eleven researchers supported by the Simons Foundation have been elected as fellows of the American Academy of Arts and Sciences. The academy is one of the oldest and …
  34. Yuri Tschinkel Elected to German National Academy of Sciences

    April 20, 2018
    Yuri Tschinkel, director of the Simons Foundation’s Mathematics and Physical Sciences division, has been elected to the Leopoldina, the German National Academy of Sciences. The honor recognizes …
  35. New Neuronal Mapping Technique Reveals Surprising Cortical Connections

    April 18, 2018
    Single cells in the visual may cortex connect to several other regions, generating a more global network than scientists previously thought.
  36. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    April 11, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  37. Watch: Madhu Sudan Studies How Complications Affect Computers When They Communicate

    April 3, 2018
    Madhu Sudan talks about exploring reliable mechanisms for computers to interact with one another.
  38. Cross-Pollination at Cosyne 2018

    April 2, 2018
    Small, single-track conferences expose scientists to research outside their comfort zone, which can invigorate them in unexpected ways.
  39. How Prior Experience Influences Working Memory

    March 28, 2018
    The posterior parietal cortex plays a role in a process called contraction bias, which controls how our sensory history shapes perception.
  40. 2018 Simons Fellows in Mathematics and Theoretical Physics Announced

    March 23, 2018
    … Brown University Antonio Montalban University of California, Berkeley Mircea Mustata University of Michigan Alexei Oblomkov University of Massachusetts Amherst Sam Payne Yale University Olga Plamenevskaya Stony Brook …
  41. Hubble Telescope Reveals Source of Gas Streaming Into Milky Way

    March 22, 2018
    The Leading Arm of the Magellanic Stream originates primarily from a nearby dwarf galaxy called the Small Magellanic Cloud
  42. Watch: Thomas Scanlon Discusses the Importance of Mathematical Logic

    March 21, 2018
    Thomas Scanlon is a professor of mathematics at the University of California, Berkeley. His work focuses on model theory and its connections to other areas of mathematics. He …
  43. Neural ‘Recycling’ Key to Short-Term Learning

    March 19, 2018
    Rather than create new neural activity patterns, the brain repurposes old ones, suggesting that short-term learning is more constrained than previously thought.
  44. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    March 14, 2018
    Each month, SCGB scans the bioRxiv for interesting papers from the SCGB community and beyond.
  45. A Step Toward Mind Reading: Decoding Perceptual Decisions as They Unfold

    March 14, 2018
    By analyzing neural activity in real time, scientists can almost instantaneously predict the likelihood that an animal will make a certain choice or change its mind.
  46. Watch: Ashvin Vishwanath Talks About the Border of Quantum Physics and Material Properties

    March 12, 2018
    Ashvin Vishawanath’s work uses quantum mechanics to explore properties of matter such as superconductivity and magnetism.
  47. “The Serengeti Rules” To Premiere at the Tribeca Film Festival

    March 9, 2018
    The Science Sandbox-supported film is scheduled to premiere at the prestigious New York City festival in April
  48. Watch: Astrophysicist Eve Ostriker Talks About Spiral Galaxies and the Interstellar Medium

    March 5, 2018
    The astrophysicist talks about the interstellar medium, star formation, galactic winds and her favorite galaxies
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