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Genetic variants in chromatin remodeling complexes are one of the most frequently attributed genetic causes of autism spectrum disorder (ASD) and intellectual disability (ID).

Atypical sensory perception is highly prevalent in individuals with autism spectrum disorder (ASD).

The exoplanet’s backward and weirdly elliptical orbit suggests that giant planets can migrate blisteringly close to their host stars long after forming in the cooler outskirts of …

In Erie, Pennsylvania, a total solar eclipse became the catalyst for something bigger—bringing people together while helping spark a new home for media art in the city.

More than 50 Science Sandbox grantees convened at the Simons Foundation for the two-day event.

The new initiative will investigate substances called catalysts that accelerate chemical reactions. The development of new catalysts could help generate clean energy and reduce the environmental impact of …

… chair Shirley M. Tilghman; and co-founder and chair Marilyn H. Simons.

Spencer Pride, located in Spencer, Indiana, put LGBTQIA+ identity at the center of their celebrations of the April 8 total solar eclipse.

The Simons Associate Program has enabled dozens of up-and-coming physicists from developing countries to expand their research networks and scope.

Virola trees in Panama are defying a well-known hypothesis from the 1970s regarding tropical biodiversity, revealing how genetics and the environment shape pathogen communities and seedling survival …

The new model developed by researchers at the Flatiron Institute proposes that biological neurons have more control over their surroundings than previously thought, something that could be replicated …

The Simons Foundation has announced the new Simons Dissertation Fellowship in Mathematics to provide research support to excellent graduate students in mathematics in the final years of their …

Neuroscientists at the Flatiron Institute and New York University developed a new theoretical framework that describes our ability to both absolutely and relatively gauge the properties of sensory …

Tech-savvy creators are flocking to New Inc. The focus is less on making art than on making it in a way that provides a living.

The funding will support researchers in answering basic scientific questions about proposed solar radiation management techniques — including identifying potentially hazardous side effects — to help policymakers make informed decisions.

On April 8, 2024, Americans witnessed a total solar eclipse that darkened the sky from Texas to Maine. We documented some of their stories as part of our …

SFARI is pleased to announce that it intends to fund 14 grants in response to the 2023 Summer Pilot Award request for applications.

The observatory’s four telescopes will make the most precise measurements ever taken of the cosmic microwave background and reveal information about what happened just after the universe …

The Simons Foundation is pleased to announce the 2024 class of Junior Fellows in the Simons Society of Fellows. These grants will be funded by the Simons Foundation …

… program is an initiative of the Leon Levy Foundation, which supports the preservation, understanding and expansion of knowledge, with a focus on the ancient world, arts and …

Stony Brook University’s Simons STEM Scholars Program celebrated the signing of its second cohort of students on May 11 at the Simons Foundation’s Flatiron Institute in …

Autism spectrum disorder (ASD) is a highly heterogeneous condition with a complex genetic basis.

Among the highly penetrant risk genes for autism spectrum disorder (ASD), many of them encode synaptic proteins and chromatin regulators.

Relative to the whole body, the brain uses 10 times more energy by weight.

For social animals and humans to thrive, they must exhibit social competence, a key component of which is adjusting behavior based on social history.

Many individuals with autism spectrum disorder (ASD) experience persistent agitation or aggression, which has an enormous impact on their and their families’ quality of life.

Several transcriptional regulator genes are strongly associated with an increased risk of autism spectrum disorder (ASD).

Functional genomic studies have identified a convergence of autism risk factors during mid-fetal cerebral cortical development1-2, a crucial period for the assembly for cortical circuits.

CRISPR promises to be a game changer in the development of treatments for genetic diseases, but sometimes the technology slices DNA where it’s not supposed to. A …

On January 8–9, 2024, SFARI welcomed researchers to its second annual meeting of the SFARI Sex Differences Collaboration (SSDC).

… Documentary Craft at Sundance and the World Wildlife Fund (WWF) Hellas Award at Thessaloniki, and went on to play at CPHDOX, HotDocs, and more. The film is …

During a 2012 interview, Simons Foundation co-founder Jim Simons discussed his life and mathematical career.

The concept behind stratospheric aerosol injection (SAI) is to inject aerosols or their precursors into the stratosphere, likely using aircraft, to increase the reflection of incoming sunlight back …

A major discussion and ongoing concern in the climate science community is to what extent the post-2020 acceleration in global mean surface temperatures reflects simple internal climate …

The team will explore the extent to which greenhouse gas-induced global warming and associated regional climate impacts could be offset by a novel solar radiation management (SRM …

Stratospheric aerosol intervention (SAI) has been proposed in addition to ambitious mitigation to increase the planet’s reflectivity to counter some of the impacts of climate change until …

This project aims at investigating the chemical and climatic impacts of alternative materials for potential solar radiation management schemes through stratospheric aerosol injections (SAI).

Stratospheric aerosol injection (SAI) involves delivering particles into the stratosphere to reflect solar radiation, thereby cooling the planet.

Despite the increasing climate risks associated with human-induced warming of the Earth’s surface, there are growing concerns about whether planned greenhouse gas (GHG) emission reductions will …

Understanding and quantifying the stratospheric heterogeneous chemistry of aerosols proposed for use in stratospheric aerosol injection (SAI) is essential for predicting the impact of SAI on stratospheric ozone …

In a world with steadily increasing atmospheric CO2 concentrations, we will soon have to drastically reduce our emissions to avoid dangerous climate change.

This project will use a climate model in different configurations to simulate mixed-phase cloud thinning, a new climate intervention proposal based on seeding supercooled liquid clouds in …

Worldwide efforts to cut greenhouse gases emissions will likely be insufficient to meet the Paris agreement goal of limiting global warming to 1.5 degrees Celsius.

By far the most researched form of stratospheric aerosol injection (SAI) is using sulfuric acid/water aerosol or its gas-phase precursors.

Cirrus cloud thinning is a potential framework to mitigate climate warming via short-lived climate forcers.

Stratospheric aerosol injection (SAI) involves the stratospheric injection of sunlight-reflecting aerosols or aerosol precursor gases that ideally possess the following material properties: (i) they do not absorb …

… report. In 2004, Simons founded a nonprofit organization committed to attracting and supporting outstanding math teachers in New York City schools. Named Math for America, the organization …

… quantitative trading and became one of the most profitable investment firms in history. He then turned his focus to making a difference in the world through the …