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    Biological Transport and Networks Integrating computation, theory and experimental data to decipher the inner workings of living processes.

    Biomolecular Design Using exotic building blocks to design novel heteropolymers that fold into well-defined 3D structures.

    Biophysical Modeling Modeling and simulating the complex systems that arise in biology and soft condensed matter physics.

    CCBScope Observatory The Flatiron Institute's in-house, state-of-the-art imaging facility for live-cell confocal microscopy.

    CCBx Uniting theorists and experimentalists to develop and test theories of biological systems.

    COMPASS Connecting researchers working on molecular sampling, simulation and design.

    Developmental Dynamics Combining experiment, theory and computing to elucidate the inner workings of embryonic development.

    Genomics Working to unravel the complexity of the genome, its regulation and its phenotypic consequences.

    Statistical Biophysics Developing a nonequilibrium physics of living systems and learning machines.

    Structural and Molecular Biophysics Developing novel mathematical approaches to decipher the molecular mechanisms involved in key biological processes.

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Flatiron Institute Computational Biology

Computational Biology: News

Stay up to date on the latest discoveries and announcements in computational biology.

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Results

  1. Mysteries of Fruit Fly Sperm Untangled by Mathematical Models

    July 22, 2026
  2. Beyond the Cryo-EM Resolution Revolution

    Watch
    June 23, 2026
  3. How Mathematical Modeling Identified Subclasses of Autism

    June 23, 2026
  4. Alumni Spotlight: Gokberk Kabacaoglu

    May 15, 2026
  5. Alumni Spotlight: Jamie Morton

    May 6, 2026
  6. Pilar Cossio: Reconstructing RNA’s Shapeshifting Behavior

    April 28, 2026
  7. The Machinery That Helps Divide Your Cells Self-Organizes Like an Active Liquid Crystal

    Watch
    February 12, 2026
  8. A Tug-of-War Explains a Decades-Old Question About How Bacteria Swim

    January 8, 2026
  9. From Ring to Keyhole: Modeling How Tissues Mold the Fruit Fly’s Gut

    Watch
    November 17, 2025
  10. New Study Reveals Subclasses of Autism by Linking Traits to Genetics

    July 9, 2025
  11. New Model Predicts How Bacteria Navigate Obstacles To Spread

    March 21, 2025
  12. Claustrophobic Cells Slow Their Own Growth, Forming Beautiful Patterns of Concentric Circles

    Watch
    October 10, 2024
  13. Physics-Informed AI Method Could Help Make CRISPR Safer

    May 20, 2024
  14. Researchers Crack Mystery of Swirling Vortexes in Egg Cells

    Watch
    April 17, 2024
  15. CCB Flatiron Research Fellow Miro Astore Awarded Young Biophysicist Award

    January 26, 2024
  16. All Five Flatiron Centers Represented at the Conference on Neural Information Processing Systems (NeurIPS)

    December 8, 2023
  17. Experiments and Mathematical Model Uncover the Mechanisms Behind Wrinkles in Cell Nuclei

    November 3, 2023
  18. Moving in Harmony

    June 21, 2023
  19. Cutting-Edge Computational Study Provides ‘Gut Check’ to How We Thought Proteins Function

    April 28, 2023
  20. Going With the Flow: Mapping Vascular Systems in Fruit Flies

    April 3, 2023
  21. Why Don’t Disease-Linked Genetic Mutations Always Result in Disease? A Study in Fruit Flies Offers New Clues

    March 13, 2023
  22. New Testing Approach Diagnoses COVID-19 With Near-Perfect Accuracy

    February 27, 2023
  23. Simons Foundation Scientists Named as Sloan Research Fellows

    February 16, 2023
  24. Computational Biology Goes Under the Microscope

    February 14, 2023
  25. Small Cell, Big Picture: Fundamental Biology Through the Lens of Simplified Models

    January 26, 2023
  26. Big Data and Powerful Computing Join Forces To Link DNA Sequence and Function

    January 24, 2023
  27. The Fruit Fly Photographer

    October 3, 2022
  28. The RNA Detective

    August 9, 2022
  29. CCB Director Michael Shelley and Simons-Supported Researchers Elected to National Academy of Sciences

    May 6, 2022
  30. New Model Shows How Cilia Make Waves

    March 17, 2022
  31. A Machine-Learning Framework for Prioritizing Disease-Associated Enhancers

    January 25, 2022
  32. A ‘Forest Fire’ Model of Cell Division Can Explain Clonal Dominance in Developing Tissue

    December 14, 2021
  33. NetQuilt: A Powerful Computational Approach for Predicting Protein Function

    October 5, 2021
  34. Fruit Fly Egg Takes an Active Hand in Its Own Growth, Highlighting Parallels to Mammals

    March 22, 2021
  35. CCB and CCM Collaborate To Create the New Structural and Molecular Biophysics Team

    February 4, 2021
  36. Mathematics Explains How Giant Whirlpools Form in Developing Egg Cells

    January 13, 2021
  37. Unveiling the Forces Behind Millions of Years of Cell Division

    December 1, 2020
  38. Finding Signals in the Noise With HumanBase

    November 10, 2020
  39. Molecular Processes in Kidney Cells May ‘Prime’ Diabetics for COVID-19 Infection

    October 23, 2020
  40. A Software, a Community and a Different Way to Do Science

    July 30, 2020
  41. Computing the Egg: The Effort To Calculate Biological Development

    July 10, 2020
  42. Plasticity May Make Neurons Vulnerable to Alzheimer’s Disease

    June 29, 2020
  43. Mutations in Uncharted Territory

    April 29, 2020
  44. Deciphering the Brain’s Algorithms

    April 9, 2020
  45. The Flatiron Institute: A Home for Computational Sciences

    March 9, 2020
  46. Beauty and the Brain

    February 5, 2020
  47. You’re Not All Human: The Wonder of Gut Microbes

    January 30, 2020
  48. Unexpected Forces Cause Rotor Proteins to Self-Organize

    December 3, 2019
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