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A study from Matthew Anderson and colleagues identified an excess of T-lymphocytes in the postmortem ASD brain, which are prominently associated with astrocytes. -
Perhaps the best-known connection between physics and symmetry is Einstein’s theory of special relativity. Superseding classical mechanics, it proposed laws about how space and time are … -
With its aesthetic appeal, symmetry has been a beacon for mathematicians and physicists. -
Cerebral fascinations: We asked our neuroscientists why they find the brain beautiful. -
… microbial communities captured in satellite imagery. The models are as beautiful as the microbes themselves, says Stephanie Dutkiewicz, a CBIOMES investigator and a principal research scientist at … -
SFARI announces that it has selected five fellows in response to the 2019 Bridge to Independence Award request for applications. -
On May 21, 2019, the recipients of the SFARI Bridge to Independence Award gathered at the Simons Foundation to discuss their scientific findings and plans in autism research. -
The finely tuned collection of bacteria, archaea and fungi collectively known as the microbiome hold an exquisite power that we are only beginning to recognize. -
As the technology to control groups of neurons matures, researchers are trying to figure out how to use it to answer neuroscience’s big questions. -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond. -
Lethal aggression is one response of male betta fish on simply seeing another male. Amy Norovich of the Simons Society of Fellows wants to identify the neurons behind … -
The Albert Einstein Society in Bern, Switzerland, will award its 2020 Einstein Medal to the international collaboration of scientists behind the Event Horizon Telescope. The prize recognizes the … -
Jennifer Raymond of Stanford University has found that the cerebellum, characterized by a simple circuit architecture, is more flexible than previously thought. -
Funds donated by SFARI to Gordon Research Conferences will now be allocated to support attendance of eligible early-career (pre-tenure) women, early-career trainees from historically underrepresented … -
The president of the Simons Foundation describes the growth of the organization and the evolution of its culture. -
The chair of the Simons Foundation describes his five principles for building a successful organization. -
Commemorating 25 years of advancing the frontiers of research in mathematics and the basic sciences -
Even the most abstract mathematics or science is surprisingly useful. But should we be surprised by that? -
Roger Bacon’s ‘three dignities’ illustrate not only how experimentation verifies and disproves theories but also how it produces new knowledge, even in mathematics. -
How can we make science a more important part of our culture? -
The new series features intimate conversations with scientists about their research and their lives. The series will launch January 22. -
SFARI is now curating a set of zebrafish lines to study autism spectrum disorder. This includes mutant lines for 12 ASD risk genes, four of which are currently … -
Newborn stars on the outskirts of our galaxy probably formed from material from two dwarf galaxies called the Magellanic Clouds. -
… together later in life within dense, busy environments. The LIGO data for the April 25 event do not indicate which of these scenarios is more likely, but … -
SFARI director Louis Reichardt will leave SFARI this coming October. -
SFARI held its 15th science meeting April 7–9, 2019. Over 100 SFARI investigators, collaborators and foundation staff convened to discuss recent findings on the genetics, molecular- and … -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
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In this blog post, Paul Wang discusses the importance of supporting the development and validation of objective clinical outcome measures for autism. He also provides an overview of … -
SFARI has awarded four grants in response to the 2019 Novel Outcome Measures in Autism Spectrum Disorder (ASD) request for applications. These grants will support the development and … -
Karel Svoboda aims to understand how neural circuits give rise to sustained activity, the neural correlate of short-term memory. -
Caroline Robertson and colleagues developed a novel paradigm that provided direct neural evidence for slower binocular rivalry in autism. They also demonstrated a causal link between GABAergic inhibition … -
A uniform call-set of joint variant calls, including single-nucleotide variants and indels, for 9,209 samples with whole-genome sequencing data from the Simons Simplex Collection … -
In amblyopia, one eye fails to provide normal input, yet the neurons in both pathways respond similarly. Mariana Cardoso of the Simons Society of Fellows thinks this discrepancy … -
Physicist Dorri Halbertal of the Simons Society of Fellows is developing new techniques to visualize physical processes at the quantum level. -
A model system exploring ATP synthase reveals that rotation, repulsion and flow can crystallize proteins. It may explain a biophysical mystery in mitochondrial membranes. -
Seemingly meaningless movements — even a quick twitch of a limb — produce abundant, widespread and high-dimensional activity in the cortex. How might the brain use this information? -
Three recent studies – two by Kristopher Kahle and Igor Medina, and the third by Xin Tang, Mriganka Sur and Rudolf Jaenisch – explored regulatory mechanisms that modulate KCC2 function … -
Daniel Geschwind, Michael Gandal and colleagues reported that allelic imbalance in gene expression in ASD shows a surprising preference for the minor allele and implicates a family of … -
… center is a research collaboration among teams that will transcend institutional and geographic boundaries. It will leverage the theoretical and computational expertise of scientists at the Flatiron … -
Each month, SCGB scans the bioRxiv and arXiv for interesting papers from the SCGB community and beyond.
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New nonlinear methods for analyzing high-dimensional neural activity can better characterize the most important patterns in the data. -
Through dance, a New York City educator is reinventing what it means for girls of color to engage with science -
Six current and past SFARI Investigators were among the 100 newly elected members of the National Academy of Medicine. -
In this blog post, Wendy Chung and John Spiro outline some of the important ways in which the Simons Searchlight program has been recently expanded, including increasing the … -
On November 3, the emperor of Japan conferred the nation’s medal of honor to physicist Hirosi Ooguri. The medal includes a purple ribbon, recognizing Ooguri’s contributions … -
The ovaries of female fruit flies contain ovarioles that serve as egg-making assembly lines. This image shows the cross-sections of 10 ovarioles from different fruit flies … -
… non-governmental support for the mathematical and physical sciences.” Eisenbud’s mathematical interests include commutative and noncommutative algebra, algebraic geometry, topology, and computer methods. Outside of mathematics … -
Last month, we gathered 24 members of the International Brain Lab (IBL), a collaboration of 21 labs across several countries, to develop shared tools for analyzing neural data …