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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. These New AI Models Are Trained on Physics, Not Words, and They’re Driving Discovery

    December 9, 2025
    While popular AI models such as ChatGPT are trained on language or photographs, new models created by researchers at the Flatiron Institute and other members of the Polymathic …
  2. Fellows-to-Faculty Alum Tomasz Nowakowski Studies Human Cortical Development

    December 8, 2025
    … other Simons Investigators. For example, I collaborate with Stephan Sanders on analyses of human postmortem brain tissue profiling. I collaborate with Omer Bayraktar to further understand which …
  3. Quanta Books To Publish Popular Math and Physics Titles by Terence Tao and David Tong

    December 8, 2025
    The books will invite readers on a tour of transformational ideas that have shaped our modern understanding of the universe.
  4. Groundbreaking Simulations Show How Black Holes Glow Bright

    December 3, 2025
    New simulations created by astrophysicists at the Flatiron Institute and the Institute for Advanced Study reveal how material flowing around and into black holes creates intense light shows …
  5. Daniel Alabi: Privacy, Computation and Beating the Drum for Mentorship

    December 1, 2025
    The former Junior Fellow in the Simons Society of Fellows supports computer science education for teenagers in his home country of Nigeria and conducts research aimed at protecting …
  6. Celebrating Mathematics: ICM2026 in Philadelphia

    November 24, 2025
    … AMS has many connections to ICM2026. One example is its administration of ICM travel grants. Another is the service of two AMS officers on the ICM2026 Organizing …
  7. Performance on a Specialized Video Game Distinguishes Children With Autism From Those With ADHD and Neurotypical Development

    November 20, 2025
    … Autism Spectr. Disord. 87, 101840 (2021) PubMed
  8. Cis-Regulation Therapy Rescues SCN2A-Related Neurological Dysfunction

    November 19, 2025
    … Neurosci. 27, 1864–1879 (2024) PubMed Karczewski K.J. et al. Nature 581, 434–443 (2020) PubMed Howe K.L. et al. Ensembl 2021. Nucleic Acids Res …
  9. Scientists Pinpoint the Moment of Decision in the Rat Brain

    November 19, 2025
    A new study tracked the activity of hundreds of neurons involved in decision-making as rats performed a trained task. Using machine learning, the researchers found a synchronized …
  10. From Ring to Keyhole: Modeling How Tissues Mold the Fruit Fly’s Gut

    November 17, 2025
    Researchers at the Flatiron Institute’s Center for Computational Biology and their collaborators from Princeton University and the Max Planck Institute in Dresden, Germany, use experimental and computational …
  11. CCN’s SueYeon Chung Named a ‘Rising Star in Neuroscience’

    November 15, 2025
    The Transmitter — an editorially independent publication of the Simons Foundation — has selected Flatiron Institute neuroscientist SueYeon Chung as one of its 2025 Rising Stars in Neuroscience. The awards …
  12. Quanta and The Transmitter Writers Win AAAS Kavli Gold Awards for Science Journalism

    November 13, 2025
    The Transmitter staff reporter Calli McMurray was recognized for her coverage of data manipulation, and Quanta contributing writer Max G. Levy won for his piece on electrostatic ecology.
  13. Simons Foundation Now Accepting Applications for Workshop on Canonical Cortical Computations

    November 13, 2025
    The Center for Computational Neuroscience (CCN) at the Flatiron Institute and the Simons Foundation Neuroscience Collaborations invite applications to participate in a workshop aimed at developing a potential …
  14. Simons Foundation Announces Fourth Class of Pivot Fellows

    November 13, 2025
    The fellowships support top researchers as they pivot to making contributions to a new discipline.
  15. Exploring Ecology, Community and Connection in the Bay Area

    November 12, 2025
    Critical Ecology Lab’s immersive Field Course reimagines what it means to study the environment while staying rooted in science, community knowledge and a deep connection to place.
  16. Mysterious ‘Impossible’ Merger of Two Massive Black Holes Explained

    November 10, 2025
    A comprehensive set of simulations by Flatiron Institute astrophysicists and their colleagues revealed that magnetic fields are responsible for creating black holes with masses in a range previously …
  17. Leslie Sibener and How Our Brains Choose Which Memories To Keep

    November 7, 2025
    Sibener, a Junior Fellow with the Simons Society of Fellows, studies how our brains prioritize which memories to hold onto and which to let go.
  18. CCA Senior Research Scientist Shirley Ho Named an AI2050 Senior Fellow by Schmidt Sciences

    November 5, 2025
    The fellowships support scholars on the cutting edge of developing AI to benefit humankind.
  19. Simons Society of Fellows Junior Fellow Thomas Werkmeister Receives Richard L. Greene Dissertation Award

    November 5, 2025
    The American Physical Society (APS) has awarded the Richard L. Greene Dissertation Award in Experimental Condensed Matter or Materials Physics to Thomas Werkmeister. The prize recognizes doctoral thesis …
  20. CCA Research Fellow Elena Pinetti Awarded Henry Primakoff Award for Early-Career Particle Physics

    November 5, 2025
    The annual award recognizes outstanding elementary particle physics research performed by a physicist who recently obtained their Ph.D.
  21. Meet Denario — An AI Assistant for Every Step of the Scientific Process

    November 4, 2025
    The new tool, developed by scientists at the Flatiron Institute, Cambridge University, the Autonomous University of Barcelona and others, leverages large language models to help scientists with tasks …
  22. Two Simons Foundation Investigators Elected to the National Academy of Medicine

    November 3, 2025
    This year’s new cohort of National Academy of Medicine members includes two investigators funded by the Simons Foundation. Election to the academy “recognizes individuals who have demonstrated …
  23. Applications for Fellows-to-Faculty Awards Now Open

    October 31, 2025
    … Computational Scientist Track: The computational science track seeks senior postdoctoral fellows with strong computational or theoretical backgrounds who aim to bring their approaches to work on key …
  24. Mapping Mouse Brains Points to How Autism Can Affect Expectation Updating

    October 23, 2025
    A new study finds that mice with variants in autism-associated genes have difficulty flexibly updating their expectations. The mice relied more on frontal brain areas associated with …
  25. Chen-Ning Yang, Nobel Prize–Winning Physicist, Dies at 103

    October 21, 2025
    Yang made important contributions to numerous fields in theoretical physics and collaborated with Jim Simons during their time at Stony Brook University.
  26. International Brain Laboratory Accepting Applications for New Collaborative Projects

    October 20, 2025
    The collaboration’s central core of scientific engineers aims to support new neuroscience research projects through data processing, analysis and visualization.
  27. Applications for Simons Postdoctoral Fellowships in Plant Biology Now Open

    October 13, 2025
    The Simons Foundation’s Life Sciences division is now accepting applications for its Simons Postdoctoral Fellowships in Plant Biology awards. The deadline for receipt of fellowship applications is …
  28. Announcing the Recipients of the Autism and Neuroscience Conferences and Courses Awards

    October 1, 2025
    … linking genes and behavior. The magnitude of this problem requires communal efforts among scientists working on different organisms and systems. Creating such synergy served as a motivation …
  29. Simons Foundation Announces Latest Class of SURFiN Fellows

    September 29, 2025
    This program provides highly motivated undergraduates with opportunities to gain first-hand research experience and career development.
  30. Announcing the Newest Cohort of Sandbox Fellows

    September 29, 2025
    The Sandbox Fellowship is an immersive program designed to support Science Sandbox awardees in growing strong foundations and enhancing their resilience.
  31. CCM Distinguished Research Scientist Stéphane Mallat Awarded CNRS Gold Medal

    September 17, 2025
    The medal recognizes Mallat’s scientific contributions, including his research into wavelets and the geometry of data.
  32. Simons Foundation Announces Recipients of 2025 Fellows-to-Faculty Awards

    September 16, 2025
    The awards help senior postdoctoral researchers with fresh perspectives on autism and neuroscience transition to tenure-track faculty positions.
  33. Amanda Hallberg Greenwell To Join Simons Foundation as Senior Vice President, External Relations

    September 16, 2025
    … of science more broadly.” Greenwell holds a B.S. in marine biology from Hawaii Pacific University in Honolulu and completed Harvard University’s Senior Managers in Government …
  34. Flatiron Institute Scientists Valentin Crépel and Ore Gottlieb Named Blavatnik Regional Award Honorees

    September 16, 2025
    Valentin Crépel of the institute’s Center for Computational Quantum Physics is the winner of the 2025 Blavatnik Regional Award for Young Scientists in the physical sciences and …
  35. Quanta Series Marvels at ‘the Achievement of Climate Science’

    September 15, 2025
    … occupy a more notable presence in the magazine’s standard coverage. “The public understanding of science is in a challenging place, but this rigorous, foundational science is …
  36. Turning El Paso, Texas, Into the World’s Science Mural Capital

    September 15, 2025
    By bringing together the worlds of biology and the arts, ART+BIO Collaborative creates immersive, multidisciplinary murals and experiences that engage communities and foster collaboration.
  37. Ringing Black Hole Confirms Einstein and Hawking’s Predictions

    September 10, 2025
    New observations of a merger of two black holes confirm decades-old predictions by Albert Einstein, Stephen Hawking and Roy Kerr. The findings emerged from analyses led by …
  38. Announcing the First Scientific Software Research Faculty Fellows

    September 2, 2025
    The program will support the creation of new software-focused professorships at academic institutions.
  39. 2025 Targeted Grants to Institutes and Targeted Grants in MPS Announced

    August 27, 2025
    The award programs support individuals and institutions working to advance mathematics and the physical sciences.
  40. From Fungi to Qubits, Pivot Fellows Share Findings in Their New Fields

    August 25, 2025
    A spring gathering of Pivot Fellows highlighted the scientific opportunities that arise from pivoting.
  41. Announcing the Recipients of the Autism Rat Models Consortium 2.0 Awards

    August 18, 2025
    The Simons Foundation Autism Research Initiative (SFARI) is pleased to announce the recipients of its Autism Rat Models Consortium 2.0 grants. This grant program will expand on …
  42. Simons Foundation Launches Collaboration on the Physics of Learning and Neural Computation

    August 18, 2025
    Under the leadership of Stanford University’s Surya Ganguli, the collaboration will study the fundamental scientific principles underlying artificial intelligence.
  43. Announcing the Simons Collaboration on Probabilistic Paths to Quantum Field Theory

    August 13, 2025
    Collaboration director Scott Sheffield of the Department of Mathematics at the Massachusetts Institute of Technology and collaboration members from other universities will work toward a unified probabilistic foundation …
  44. A Stellar Revolution: How Open-Source Tool MESA Changed the Way We Study Stars

    August 12, 2025
    Since its creation by retired Silicon Valley software designer Bill Paxton, the Modules for Experiments in Stellar Astrophysics (MESA) has illuminated the lives of stars and become a …
  45. How a Tiny Brain Region Helps You Learn Complex Movements, One Neuron at a Time

    August 11, 2025
    A new study finds that as mice learn a complex movement, the pathway from a deep brain region called the motor thalamus to the motor cortex rewires itself …
  46. New Simons Collaboration Explores Black Holes and Strong Gravity

    August 11, 2025
    Nicolás Yunes of the University of Illinois Urbana-Champaign will lead the collaboration’s work to better understand the physics of strong gravity, such as that of black …
  47. Introducing Infinite Sums, A National Initiative Celebrating Mathematics

    August 8, 2025
    The initiative will connect communities across the United States with opportunities to engage with math through cultural experiences.
  48. Simons Foundation Accepting Applications for Simons Collaborations in Ecology and Evolution

    August 4, 2025
    The Simons Foundation’s Life Sciences division is now accepting applications for its Simons Collaborations in Ecology and Evolution awards. The deadline for receipt of vision statements is …
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