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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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Featured

Dissecting mechanisms of hyperarousal in autism and related disorders using the Simons Sleep Project

Funded Work

Gravity Follows Newton’s and Einstein’s Rules, Even at Cosmic Scales

April 15, 2026

Scientists Capture Superconductivity’s ‘Dancing Pairs’ for First Time, Filling Gap in Decades-Old Theory

April 15, 2026

How SURFiN Fellowships Jump-Started These 3 Neuroscience Students’ STEM Careers

March 18, 2026

Results

  1. Caught in the Act: Astronomers Watch a Vanishing Star Turn Into a Black Hole

    February 12, 2026
    A team of astronomers led by the Flatiron Institute’s Kishalay De discovered that a star in the Andromeda Galaxy disappeared without going supernova, and instead collapsed directly …
  2. The Machinery That Helps Divide Your Cells Self-Organizes Like an Active Liquid Crystal

    February 12, 2026
    Flatiron Institute scientists and experimental collaborators tested a theory that treats chromosome-separating cellular structures called spindles as active liquid crystals. They found that the theory largely succeeds …
  3. Multimodal Approach Reveals How Autism-Linked Genes Shape Primate Prefrontal Cortex Development

    February 12, 2026
    SFARI-funded research finds that RAPGEF4 is a key molecular regulator orchestrating prefrontal cortical maturation in primates.
  4. Beetles Steal the Scent of Ants to Secretly Live Among Them

    National Geographic
    New research examines a newly characterized beetle species, Sceptobius, that lives in a symbiotic relationship with ant colonies, and finds that Sceptobius infiltrates ant colonies by developing an …
  5. Simons Searchlight February 2026 Update: New Phenotypic Data Available

    February 5, 2026
    The Simons Foundation Autism Research Initiative (SFARI) is pleased to announce a new data release from Simons Searchlight aimed at improving the scientific understanding of autism.
  6. Human Assembloid Model Reveals Region-Specific Effects of an Epilepsy-Linked Mutation

    February 5, 2026
    SFARI-funded research demonstrates that SCN8A mutations underlying DEE-13 disrupt both cortical and hippocampal networks, but in distinct ways.
  7. NYU Launches Simons Center for Computational Geophysical Flows

    February 3, 2026
    The interdisciplinary research and training hub will work to unlock the mysteries of planetary climates.
  8. One of Earth’s Most Abundant Organisms Is Surprisingly Fragile

    The Microbiologist
    A group of ocean bacteria long considered perfectly adapted to life in nutrient-poor waters may be more vulnerable to environmental change than scientists realized.
  9. Biological Brains Inspire a New Building Block for Artificial Neural Networks

    January 26, 2026
    While artificial intelligence systems have advanced tremendously in recent years, they still lag behind the performance of real brains in reliability and efficiency. A new type of computational …
  10. Math Meets Couture: Infinite Sums and Iris van Herpen at the Brooklyn Museum

    January 23, 2026
    The Simons Foundation is partnering with the Brooklyn Museum to highlight the math behind fashion designer Iris van Herpen’s Sculpting the Senses exhibition.
  11. Adrian Bayer: Unveiling the Universe’s Origins and Current State by Modeling Its Many Faces

    January 21, 2026
    Inspired by a desire to understand how things work, Flatiron Research Fellow Adrian Bayer studies the structure of galaxies and the remnant heat from the universe’s creation …
  12. Hidden Order in Quantum Confusion: The Pseudogap

    January 19, 2026
    Quantum simulator using ultracold atoms reveals how subtle magnetic patterns shape one of the most puzzling states of matter.
  13. 2025 Autism Rat Consortium Meeting Held in New York City

    January 13, 2026
    On September 29, 2025, the SFARI Autism Rat Consortium (ARC) held its annual meeting in the Usher Institute of the University of Edinburgh. This year’s event brought …
  14. Announcing the 2026 Simons Foundation Presidential Lecture Series

    January 12, 2026
    The public lecture series highlights the latest research in mathematics and the basic sciences.
  15. A Tug-of-War Explains a Decades-Old Question About How Bacteria Swim

    January 8, 2026
    Bacteria tails rotate counterclockwise to propel the bacteria through liquid environments and clockwise to change direction. Previous research has suggested that the direction of the spin depends on …
  16. Most Planets in Our Galaxy Are Born ‘Bloated’, New Study Suggests, BBC Science Focus

    In the News
    Astronomers may have uncovered how the most common types of planets in our galaxy grow. The discovery confirms astronomers’ theories that these planets start as 'bloated' babies but …
  17. Fellows-to-Faculty Awardee Sama Ahmed Studies the Neuroscience of Multitasking

    January 6, 2026
    … who studies power, and they talked about how important hierarchies are if you need something to happen quickly. But if you want things to be done in …
  18. There Are Two Possible Futures for American Science

    Issues in Science and Technology
    Simons Foundation president David Spergel talks about the evolving landscape for science philanthropy, his outlook for the research enterprise, and remaining hopeful in an uncertain time.
  19. Neural tracking of acoustic-prosodic content in speech in adults with high-functioning ASD

    Funded Work
    A key manifestation of social communication deficits in autism spectrum disorder (ASD) is impaired perception of speech prosody.
  20. SCOPE Synthesis: Impacts of viruses and grazers on marine picophytoplankton

    Funded Work
  21. SCOPE Synthesis: Molecular perspectives on microbial chemical energy fluxes in the upper ocean

    Funded Work
  22. SCOPE Synthesis: How nutrient supply rate and ratio shape diazotroph and non-diazotroph activity

    Funded Work
  23. SCOPE Synthesis: Multimodal data integration

    Funded Work
  24. SCOPE Synthesis: Effects of nutrient availability on heterotrophic bacterial metabolism and remineralization processes in the oligotrophic North Pacific Ocean

    Funded Work
  25. SCOPE Synthesis: Advancing our understanding of ocean productivity from cells to biomes

    Funded Work
  26. SCOPE Synthesis: Integrating zooplankton into our understanding of microbial community structure and stoichiometry along gradients in the Pacific Ocean

    Funded Work
  27. SCOPE Synthesis: Linking microbial physiological ecology to ecosystem functions in the NPSG

    Funded Work
  28. SCOPE Synthesis: Statistical Learning Along Oceanographic Transects

    Funded Work
  29. Directly Learning Global Biogeochemical Microbe Distributions and Ecology from Flow Cytometry

    Funded Work
  30. Biogeochemical cycling of ubiquitous dissolved organic matter-derived polysaccharides in marine plankton

    Funded Work
  31. Simons Foundation Announces 3 New Scientific Software Research Faculty Fellows

    January 5, 2026
    The program provides institutions with financial support to create new software-focused positions.
  32. From Ringing Black Holes to Restoring Gut Health: Science at Simons in 2025

    December 22, 2025
    A look back at the year’s biggest discoveries and defining stories.
  33. Simons Searchlight at 15: A Researcher’s Guide

    December 18, 2025
    Simons Searchlight offers open-source data and tools to researchers worldwide who study autism and related neurodevelopmental conditions.
  34. A Quantum Trick Helps Trim Bloated AI Models

    Science News
    Tensor networks grapple with the complexities of both quantum particles and machine learning.
  35. Fellows-to-Faculty Awardee Abhilasha Joshi Maps Cognitive-Motor Flexibility Across the Aging Brain

    December 17, 2025
    … that was linked to me, rather than an institution, supported me to act on my thoughts of applying to faculty positions in India and elsewhere. What else …
  36. Autism and Neuroscience Innovators: Awardees Share Their Research at the Annual Retreat

    December 15, 2025
    … has shown that this inhibitory synchronicity is indeed a driver of seizure vulnerability. Mapping the Senses of Internal Organs Fellows-to-Faculty member Chen Ran, an assistant …
  37. Fellows-to-Faculty Alum Gabriela Rosenblau Dives Deep Into Social Learning in Autism

    December 11, 2025
    … fellowship encouraged you to collaborate with people in different fields? Absolutely. Once a year or twice a year, for as long as you’re a grantee, you …
  38. These New AI Models Are Trained on Physics, Not Words, and They’re Driving Discovery

    December 9, 2025
    While popular AI models such as ChatGPT are trained on language or photographs, new models created by researchers at the Flatiron Institute and other members of the Polymathic …
  39. Fellows-to-Faculty Alum Tomasz Nowakowski Studies Human Cortical Development

    December 8, 2025
    … other Simons Investigators. For example, I collaborate with Stephan Sanders on analyses of human postmortem brain tissue profiling. I collaborate with Omer Bayraktar to further understand which …
  40. Quanta Books To Publish Popular Math and Physics Titles by Terence Tao and David Tong

    December 8, 2025
    The books will invite readers on a tour of transformational ideas that have shaped our modern understanding of the universe.
  41. To Boost Research, States Are Building Their Own AI-Ready Supercomputers

    Science
    New York aims to democratize access to hardware often limited to federal labs and Big Tech.
  42. Groundbreaking Simulations Show How Black Holes Glow Bright

    December 3, 2025
    New simulations created by astrophysicists at the Flatiron Institute and the Institute for Advanced Study reveal how material flowing around and into black holes creates intense light shows …
  43. Daniel Alabi: Privacy, Computation and Beating the Drum for Mentorship

    December 1, 2025
    The former Junior Fellow in the Simons Society of Fellows supports computer science education for teenagers in his home country of Nigeria and conducts research aimed at protecting …
  44. Celebrating Mathematics: ICM2026 in Philadelphia

    November 24, 2025
    … AMS has many connections to ICM2026. One example is its administration of ICM travel grants. Another is the service of two AMS officers on the ICM2026 Organizing …
  45. Performance on a Specialized Video Game Distinguishes Children With Autism From Those With ADHD and Neurotypical Development

    November 20, 2025
    … Autism Spectr. Disord. 87, 101840 (2021) PubMed
  46. Cis-Regulation Therapy Rescues SCN2A-Related Neurological Dysfunction

    November 19, 2025
    … Neurosci. 27, 1864–1879 (2024) PubMed Karczewski K.J. et al. Nature 581, 434–443 (2020) PubMed Howe K.L. et al. Ensembl 2021. Nucleic Acids Res …
  47. Scientists Pinpoint the Moment of Decision in the Rat Brain

    November 19, 2025
    A new study tracked the activity of hundreds of neurons involved in decision-making as rats performed a trained task. Using machine learning, the researchers found a synchronized …
  48. How Sensory Processing Works: Neurons May Predict the Future and Remember the Past, Daily Neuron

    In the News
    A new paper, researchers at the Flatiron Institute, NYU Langone, and Rutgers University propose that sensory neurons are not just passive filters but active, “self-supervised learners“. Their …
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