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  • Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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Bringing people and ideas together to fund, conduct, and share transformative science.

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Founded by Jim and Marilyn Simons, we’re a private philanthropy advancing mathematics and basic science.

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The Flatiron Institute is a research center that uses computational science to advance fields like physics, biology, and astronomy.

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  1. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    October 25, 2019
  2. SFARI Summer 2019 Pilot Awardees Announced

    September 30, 2019
  3. Targeting Somatosensory Over-Reactivity in Mouse Models of ASD

    September 30, 2019
  4. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    September 30, 2019
  5. Predicting Aggression With Wearable Biosensors

    September 30, 2019
  6. Aberrant Neocortical Connectivity in Shank3 Mutant Mice

    September 27, 2019
  7. ‘Ringing’ Black Hole Validates Einstein’s General Relativity 10 Years Ahead of Schedule

    September 12, 2019
  8. SPARK Pilot Study Identifies Novel Candidate Autism Risk Genes

    September 3, 2019
  9. Mystery Solved About the Machines That Move Your Genes

    September 2, 2019
  10. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    August 26, 2019
  11. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    August 19, 2019
  12. A Stellar Stream in the Milky Way Provides Evidence of Dark Substructure

    July 29, 2019
  13. Frustrated Fish Reveal Glia’s Computational Role in Motivated Behavior

    July 29, 2019
  14. Unexpected Synaptic Role for the Autism Risk Gene Scn2a

    July 26, 2019
  15. A Pipeline for Functional Assessment of Autism-Associated Missense Mutations in C. Elegans

    July 24, 2019
  16. Distinct Patterns of Connectivity Underlie Differences in Sensory Responsiveness in Autism

    July 24, 2019
  17. A Mouse Model of 22q11.2 Deletion Syndrome Shows Reduced Long-Range Connectivity and Dysfunctional Mitochondria

    July 12, 2019
  18. Two Studies Using SPARK’s Research Matching Program Attest to Its Effectiveness for Rapid and Large-Scale Testing of Research Questions

    July 12, 2019
  19. Brief Treatment With Statin Yields Long-Term Benefit in Rat Model of Fragile X Syndrome

    July 12, 2019
  20. Single-Nucleus RNA Sequencing Identifies Brain Cell Types With Significant Changes in Gene Expression in Autism

    July 10, 2019
  21. Pair of Supermassive Black Holes Discovered on a Collision Course

    July 10, 2019
  22. Substantial Role for Biallelic Mutations in Autism Risk, Particularly in Females

    July 3, 2019
  23. How Important Is Spike Sorting?

    July 1, 2019
  24. Power Law Discovery May Explain Why You Can See the Forest and the Trees

    June 26, 2019
  25. The First AI Simulation of the Universe Is Fast and Accurate — and Even Its Creators Don’t Know How It Works

    June 26, 2019
  26. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    June 21, 2019
  27. A Genome-Wide Assessment of Noncoding Risk Variants in Autism

    June 11, 2019
  28. Laser-Controlled Novel Superconductors Could Help Pave the Way to Quantum Computers

    June 4, 2019
  29. Neurons From Individuals With SHANK2-Associated Autism Exhibit Increased Neuronal Connectivity

    May 31, 2019
  30. Development of a Single-Cell Mouse Cortical Gene Expression Pattern Resource That Identifies Putative Brain Disorder Subtypes

    May 31, 2019
  31. New Causes of Autism Found in ‘Junk’ DNA

    May 27, 2019
  32. Recurrent Connections Improve Neural Network Models of Vision

    May 23, 2019
  33. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    May 22, 2019
  34. Grid Cells Encode Both Meaning and Position

    April 24, 2019
  35. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    April 23, 2019
  36. How ALS Progresses on Genetic and Cellular Level Revealed by High-Res Spinal Cord Study

    April 4, 2019
  37. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    March 22, 2019
  38. Cryptic Splice Mutations: A Major New Source of Risk Variants for Neurodevelopmental Disorders

    March 20, 2019
  39. Impaired Reward Circuitry During Voice Processing Predicts Social Communication Abilities in Autism

    March 20, 2019
  40. Largest Genome-Wide Association Study Yields Common Variants Associated With Risk of Autism

    March 19, 2019
  41. Multitasking Neural Networks Balance Specialization With Flexibility

    March 19, 2019
  42. Open-Source Software Tracks Neural Activity in Real Time

    February 28, 2019
  43. Scientists Provide New Insight on How the Nose Adapts to Smells

    February 26, 2019
  44. Meta–Analysis of De Novo Mutations Yields Longer List of Risk Genes for Neurodevelopmental Disorders

    February 25, 2019
  45. Large-Scale SSC Whole-Genome Sequencing Data Key to Identifying Statistically Significant De Novo Noncoding Variation in Autism

    February 25, 2019
  46. Alterations in Neuronal Excitability Are Compensatory Changes, Not Causal Effects, in Autism

    February 25, 2019
  47. Gravitational Waves Will Settle Cosmic Conundrum

    February 14, 2019
  48. From the bioRxiv: A Selection of Recently Posted Papers From SCGB Investigators and Others

    February 13, 2019
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