Simons Foundation

advancing research in basic sciences and mathematics

News

Latest News

  • Special skill: Colleagues say Cathy Lord has an instant rapport with children on the autism spectrum.
    spotlight

    In the late 1960s, as an undergraduate student in psychology at the University of California, Los Angeles, Cathy Lord spent a couple of hours a day teaching two young boys with autism.

    She was working for clinical psychologist Ole Ivar Lovaas, one of a few doctors who believed in behavioral therapy for...

    30 Jun 2008 .:. 0 comments
  • In oxytocin we trust: Prompted by reports of the hormone's effects on social bonding, parents are giving it to children with autism.
    news

    The so-called trust hormone oxytocin could prove to be an effective treatment for autism, but it’s premature for parents to be dosing their kids with the hormone, researchers warn.

    Giving people oxytocin has shown that the hormone boosts the willingness to trust others. Animal studies and small clinical trials have also linked...

    25 Jun 2008 .:. 0 comments
  • A film studio logo, also designed by a child on the spectrum using Google SketchUp.
    news

    In February 2006, psychology researcher Gary Mesibov introduced an electronic diary to a few teens with autism at his clinic in Chapel Hill, North Carolina.

    The diary, a personal digital assistant (PDA), was programmed to help the teens track their performance in school and interact with their peers. Mesibov and his collaborators...

    20 Jun 2008 .:. 0 comments
  • There is a striking difference in the magnitude of excitatory post-synaptic current evoked from hippocampal neurons of the Rett syndrome mouse model (red) and the MeCP2 duplication mouse model (blue). The averaged current from normal mice is in black. (DIV=days in vitro)
    news

    The gene underlying Rett syndrome has a surprisingly large role in controlling the activity of other genes, according to two recent papers.

    The findings have dismayed some researchers, who say the condition may be more difficult to treat than previously thought.

    Rett syndrome is a rare neurological condition that shares some symptoms, such...

    16 Jun 2008 .:. 0 comments
  • Picture imperfect:  Individuals with autism (right) have lower activity in some brain regions  compared with controls (left).
    news

    Repetitive behaviors seen in adults with autism are associated with abnormal activity in the ‘executive’ brain system, which is responsible for attention, planning and for inhibiting inappropriate behaviors, according to an imaging study published in May1.

    About 80 percent of adults with autism exhibit restricted or repetitive behavior such as hand...

    11 Jun 2008 .:. 1 comment
  • Unlucky breaks: De novo mutations can account for schizophrenia in families with no prior history of the disease.
    news

    Rare, spontaneous mutations could account for at least 10 percent of cases of schizophrenia, according a study published online last week1.

    These mutations are deletions or duplications of DNA segments, dubbed copy number variations (CNVs).

    Although submicroscopic in stature, CNVs have for the past two years been implicated in neurological disorders such...

    05 Jun 2008 .:. 0 comments
  • All for one: Scientists are divided over whether autism's features
are caused by a single defect or by three separate pathways.
    news

    Every day, Tamarack O’Donnell works with children who span the range of disorders on the autism spectrum. Some children flap their hands and cannot engage even in basic social interactions; others are visibly intelligent and have only mild eccentricities, such as eating only out of a green bowl.

    After working with 100...

    02 Jun 2008 .:. 0 comments
  • Split the difference: New evidence suggests
autism and schizophrenia may be closely related.
    news

    For much of the twentieth century, autism was considered childhood schizophrenia.

    Shared problems with language and social interaction lumped them together. Doctors thought as the children grew older, they simply became more psychotic and delusional.

    But, in 1943, Leo Kanner, a psychiatrist at Johns Hopkins University, suggested that children who have an “innate...

    27 May 2008 .:. 1 comment

More News

From the blog: On SFARI

  • blog

    Let me first apologize for not having updated the blog in a few days. I was away getting married last weekend, while news in the world of autism piled up...

    Last month, while I was distracted, researchers reported in the journal Developmental Cell that the protein that’s missing in those with fragile...

    02 Jul 2008 .:. 0 comments
  • blog

    In the past few days, the New York Times has run a couple of articles featuring people with autism.

    This isn’t unusual in of itself, except that neither article ran in the health section. And both take a compassionate look at individuals who struggle with autism in profound ways.

    The first, which ran...

    19 Jun 2008 .:. 0 comments
  • blog

    Try this on for size: the human brain has about 100 billion neurons, connected by 100 trillion synapses.

    We already knew that the human brain has many more neurons than the brain of any other animal, and is three times as large as even its closest relative, the chimpanzee.

    In a paper in...

    13 Jun 2008 .:. 0 comments
  • blog

    Autism is sometime called the result of an ‘extreme male brain’.

    And the classic traits associated with the disorder — social awkwardness and obsessive interests, for example — are associated with, and better tolerated in, men than in women.

    Add to this the statistics — that autism affects four times as many boys...

    10 Jun 2008 .:. 0 comments
  • blog

    Between Thursday and Sunday last week, New York played host to the first annual World Science Festival, a fantastic lineup of events featuring more than 125 of the world’s most brilliant and original thinkers.

    Full disclosure: The Simons Foundation is one of the festival's sponsors. But that doesn't take away from the...

    04 Jun 2008 .:. 0 comments
  • blog

    Everyone in the scientific community is talking about Francis Collins’ unexpected decision to step down on 1 August as director of the US National Human Genome Research Institute.

    Collins is a giant among geneticists, and championed many pivotal projects including, most notably, the Human Genome Project. Among his newer ventures are the...

    29 May 2008 .:. 2 comments
  • blog

    When we write news articles for this website, we sometimes struggle with the most respectful and appropriate language to use in talking about autism.

    We would never call people who have a disease “patients”, for example, because it is dehumanizing, but the lines get blurrier.

    Is it better to refer to “children with...

    28 May 2008 .:. 1 comment
  • blog

    I try not to spend too much time on the vaccine theories because as far as I’m concerned, they’re well-trod territory: all evidence suggests that neither thimerosal, nor the triple jab for mumps-measles-rubella (MMR) causes autism.

    But occasionally, events in the world force me to address the issue. Last week, a special...

    19 May 2008 .:. 0 comments

More from On SFARI