Center for Computational Biology

Simons Foundation

The Center for Computational Biology develops new and innovative methods of examining data in the biological sciences whose scale and complexity have historically resisted analysis.

CCB’s mission is to develop modeling tools and theory for understanding biological processes and to create computational frameworks that will enable the analysis of the large, complex data sets being generated by new experimental technologies.

Groups

Biophysical Modeling The Biophysical Modeling group focuses on the modeling and simulation of complex systems that arise in biology and soft condensed matter physics. Read More

Genomics An immensely complex molecular network of interactions forms the foundation of human biology and disease. Genomic approaches provide a particularly illuminating window to biological systems, and when combined with advanced analysis allow us to learn and model this complexity. Read More

Neuroscience Our goal is to understand how the brain analyzes large and complex datasets streamed by sensory organs in order to aid efforts at building artificial neural systems and treating mental illness. Read More

Systems Biology At the Systems Biology group, we are developing new methods to learn the networks that run life’s program. Read More

News & Announcements

Deep Beneath Your Feet, They Live in the Octillions (New York Times)

The Author File: Olga Troyanskaya (Nature Methods)

DNA ‘Dances’ in First Explanation of How Genetic Material Flows Through a Nucleus By Thomas Sumner

Research Highlights

February 1, 2019

From cytoskeletal assemblies to living materials

P. Foster, S. Fürthauer, M. Shelley, D. Needleman

Many subcellular structures contain large numbers of cytoskeletal filaments. Such assemblies underlie much of cell division, motility, signaling, metabolism, and…

Current Opinion in Cell Biology

January 1, 2019

Dynamics of Flexible Fibers in Viscous Flows and Fluids

O. Du Roure, A. Lindner, E. Nazockdast, M. Shelley

The dynamics and deformations of immersed flexible fibers are at the heart of important industrial and biological processes, induce peculiar…

Annual Review of Fluid Mechanics

December 24, 2018

The free surface of a colloidal chiral fluid: waves and instabilities from odd stress and Hall viscosity

V. Soni, E. Bililign, S. Magkiriadou, S. Sacanna, D. Bartolo, M. Shelley, W. Irvine

In simple fluids, such as water, invariance under parity and time-reversal symmetry imposes that the rotation of constituent ‘atoms’ are…

arXiv:1812.09990

Director

Leslie Greengard, M.D., Ph.D.

Director, CCM; Interim Director, CCB

Leslie Greengard joined the Simons Foundation in 2013 as founding director of the Simons Center for Data Analysis, now called the Center for Computational Biology. Prior to that, Greengard served as director of the Courant Institute of Mathematical Sciences at New York University.

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