The Center for Computational Biology develops new and innovative methods of examining data in the biological sciences whose scale and complexity have historically resisted analysis.
CCB’s mission is to develop modeling tools and theory for understanding biological processes and to create computational frameworks that will enable the analysis of the large, complex data sets being generated by new experimental technologies.
Background Motion correction is a challenging pre-processing problem that arises early in the analysis pipeline of calcium imaging data sequences.…Journal of Neuroscience Methods
Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with a strong genetic basis. Yet, only a small fraction of…Nature Neuroscience
In cryo-electron microscopy, the 3D electric potentials of an ensemble of molecules are projected along arbitrary viewing directions to yield…arXiv:1710.09791