Understanding the human brain is one of the greatest and most challenging scientific frontiers of our time. CCN’s mission is to develop models, principles and conceptual frameworks that deepen our knowledge of brain function — both in health and in disease.
Featured News

Flatiron data scientist Billy Broderick is on a mission to make neuroscience research easier and more efficient by developing user-friendly software for analyzing and modeling data.
CCN takes a “systems" neuroscience approach, building models that are motivated by fundamental principles, that are constrained by properties of neural circuits and responses, and that provide insights into perception, cognition and behavior. This cross-disciplinary approach not only leads to the design of new model-driven scientific experiments, but also encapsulates current functional descriptions of the brain that can spur the development of new engineered computational systems, especially in the realm of machine learning. CCN currently has research groups in Computational Vision and Neural Circuits and Algorithms, and will launch research groups in NeuroAI and Geometry and Statistical Analysis of Neural Data in January 2022.
Research




Collaborative Work
News & Announcements
August 07, 2023
April 26, 2023
Upcoming Events
-
27 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
04 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
11 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
18 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
19 Thu -
Event 2:30 - 3:30 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 3:30 p.m.
-
25 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
01 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
08 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
15 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
-
22 Wed -
Event 2:30 - 5:00 p.m.
Online Community Meeting for Calcium and Voltage Imaging Analysis
-
Event 2:30 - 5:00 p.m.
Research Highlights
Coordinated drift of receptive fields in Hebbian/anti-Hebbian network models during noisy representation learning
Recent experiments have revealed that neural population codes in many brain areas continuously change even when animals have fully learned…
Nature NeuroscienceComputational mechanisms of distributed value representations and mixed learning strategies
Learning appropriate representations of the reward environment is challenging in the real world where there are many options, each with…
Nature CommunicationsNeural optimal feedback control with local learning rules
A major problem in motor control is understanding how the brain plans and executes proper movements in the face of…
NeurIPSLeadership
Software

CaImAn Python
Computational toolbox for large scale Calcium Imaging Analysis, including movie handling, motion correction, source extraction, spike deconvolution and result visualization.

CaImAn-MATLAB
Complete Matlab pipeline for large scale calcium imaging data analysis.

Chunkflow
Modern imaging methods, such as Light, Electron, and synchrotron X-ray, have enabled 3D imaging for large samples with high resolution.

p l e n o p t i c
`plenoptic` is a python library for model-based stimulus synthesis.

RealNeuralNetworks.jl
Due to the string-like nature of neurons and blood vessels, they could be abstracted as curved tubes with center lines and radii.