Computer Vision Interest Group Seminar: “Scalable and Flexible Connectomics Segmentation with PyTorch Connectomics” (Zudi Linn, Harvard University)

Date & Time

Presenter: Zudi Linn, Harvard University

Title: Scalable and Flexible Connectomics Segmentation with PyTorch

ConnectomicsWe present PyTorch Connectomics (PyTC), an open-source deep-learning framework for the semantic and instance segmentation of volumetric microscopy images, built upon PyTorch. We demonstrate the effectiveness of PyTC in the field of connectomics, which aims to segment and reconstruct neurons, synapses, and other organelles like mitochondria at nanometer resolution for understanding neuronal communication, metabolism, and development of animal brains. PyTC is a scalable and flexible toolbox that tackles datasets at different scales and supports multi-task and semi-supervised learning to better leverage valuable expert annotation and the vast amount of unlabeled data. Those functionalities can be easily realized in PyTC by changing the configuration options without coding and adapted to other 2D and 3D segmentation tasks for different tissues and imaging modalities. Our framework achieves the best performance in the CREMI challenge for synaptic cleft segmentation and competitive performance on the neuron, mitochondria, and nuclei segmentation. Code and tutorials are publicly available at

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