Simons Foundation

Publications

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Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors

Laura Gallego-Yerga, Rodrigo Ochoa, Isaías Lans, Carlos Peña-Varas, Melissa Alegría-Arcos, P. Cossio, David Ramírez, Rafael Peláez

Decoding disease: from genomes to networks to phenotypes

A. Wong, R. Sealfon, Chandra L. Theesfeld, O. Troyanskaya

Opposing effects of selectivity and invariance in peripheral vision

Corey M. Ziemba, E. P. Simoncelli

ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements

X. Chen, Andrew F. Neuwald, Leena Hilakivi-Clarke, Robert Clarke, Jianhua Xuan

Realizing a dynamical topological phase in a trapped-ion quantum simulator

P. Dumitrescu, Justin Bohnet, John Gaebler, Aaron Hankin, David Hayes, Ajesh Kumar, Brian Neyenhuis, Romain Vasseur, Andrew C. Potter

Machine learning methods to model multicellular complexity and tissue specificity

R. Sealfon, A. Wong, O. Troyanskaya

CROTON: an automated and variant-aware deep learning framework for predicting CRISPR/Cas9 editing outcomes

Victoria R Li, O. Troyanskaya, Z. Zhang

Experiences and lessons learned from two virtual, hands-on microbiome bioinformatics workshops

Matthew R Dillon, Evan Bolyen, Anja Adamov, J. Morton, R. Bonneau, et al.

Temporal integration of inductive cues on the way to gastrulation

Sarah McFann, Sayantan Dutta, Jared E. Toettcher, S. Shvartsman

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Parisa Hosseinzadeh, Paris R. Watson, Timothy W. Craven, V. Mulligan, et al.

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