Vikram K. Mulligan, Ph.D.
Research Scientist, Biomolecular Design, CCB, Flatiron Institute![Portrait photo of Vikram Mulligan](https://simonsfoundation.imgix.net/wp-content/uploads/2018/09/26152516/Mulligan_Vikram.jpg?auto=format&w=120&h=120&fit=crop&crop=faces&q=90)
Vikram Mulligan completed his Ph.D. in the Department of Biochemistry at the University of Toronto, working in the lab of Avi Chakrabartty on molecular mechanisms of protein misfolding in late-onset neurodegenerative diseases. As a postdoc at the University of Washington, he worked to generalize the Rosetta software suite to permit design of mixed-chirality peptide macrocycles, and created the first de novo designed mixed-chirality macrocycles able to bind to a target of therapeutic interest (the New Delhi metallo-β-lactamase 1, an antibiotic resistance factor). Mulligan’s ongoing research interests include harnessing quantum computers to solve the most poorly-scaling problems in protein and heteropolymer modeling, developing methods for rationally designing molecular motions, and incorporating quantum mechanical calculations into classical design pipelines. With Douglas Renfrew, Mulligan co-heads the Biomolecular Design Group.