Department of Biochemistry and Biophysics,
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco
This talk discusses progress in developing devices that can restore lost functions of the nervous system following disease or injury, in particular the development of a brain computer interface (BCI) that is designed to restore independence and control for people with paralysis.
Analyzing the collective behavior and social interactions of hundreds of millions of people with powerful computational techniques offers a radically new perspective on fundamental questions in the social sciences.
Fundamental gaps remain in our understanding of animal brains, especially human brains, in comparison with other organ systems in the body. One of these gaps is our very partial knowledge of the circuit architecture of brains, even in the best studied model organisms.
Can efficient algorithms find approximately optimal solutions? The classical theory of NP-completeness didn't address or preclude this possibility.
This talk presents a strategy based on systematic gene perturbation and innovative multiplex detection to derive regulatory networks in mammalian cells.