The Geometry of Multicellular Life
- Speaker
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Raymond E. Goldstein, Ph.D.Alan Turing Professor of Complex Physical Systems, Department of Applied Mathematics and Theoretical Physics, University of Cambridge
Scientific Advisory Board, Flatiron Institute
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One of the most fundamental issues in evolutionary biology is how unicellular life transitioned to multicellular life. How — and why — was it that the simplest single-celled organisms that emerged from the primordial soup evolved into organisms with many cells and cell types dividing up life’s processes?
In this Presidential Lecture, Ray Goldstein will describe recent experimental and theoretical advances in understanding the architecture of organisms that serve as models of this evolutionary transition. He will discuss the shape-shifting properties of certain choanoflagellates (the closest living relatives of animals) and the recent discovery of common probability distributions of cellular neighborhood volumes in yeast and alga. He will also discuss embryonic ‘inversion’ and the spontaneous curling of the extracellular matrix of green algae. These studies together shed light on the fundamental question, “How do cells produce structures external to themselves in an accurate and robust manner?”