Exploring Cancer Drivers and Dependencies

  • Speaker
  • The Scott Lowe Lab, Cancer Biology & Genetics Program; Sloan Kettering Institute (SKI)Scott W. Lowe, Ph.D.Chair, Geoffrey Beene Cancer Research Center, Memorial Sloan-Kettering Cancer Center
Date & Time


About Simons Foundation Lectures

Simons Foundation Lectures are free public colloquia related to basic science and mathematics. These high-level talks are intended for professors, students, postdocs and business professionals, but interested people from the metropolitan area are welcome as well.

The human body contains gene networks that naturally inhibit tumor development. This defensive arsenal includes repairing damaged DNA, suppressing inflammation and triggering the self-destruction of cells.

In this lecture, Scott W. Lowe will discuss his lab’s work exploring how the genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response and create vulnerabilities that may be targeted therapeutically. He will outline how his team combines genetic, genomic and animal model approaches to comprehensively study cancer biology. He will also discuss tumor-suppressor gene networks and strategies to restore their function in advanced cancers.

About the Speaker

The Scott Lowe Lab, Cancer Biology & Genetics Program; Sloan Kettering Institute (SKI)

Lowe is the chair of the Cancer Biology and Genetics Program at Memorial Sloan Kettering Cancer Center (MSKCC) and investigator in the Howard Hughes Medical Institute. He received his B.S. from the University of Wisconsin-Madison, and his Ph.D. from the Massachusetts Institute of Technology. Before joining MSKCC, Lowe was a faculty member at Cold Spring Harbor Laboratory in New York. He is a member of the American Academy of Arts and Sciences and the National Academy of Sciences.

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