Our grantmaking efforts focus on mathematical and physical sciences, life sciences, neuroscience and autism research.
Pivot Fellowship Request for Applications
The fellowship will enable today’s brightest minds to apply their talent and expertise to a new field, and will consist of one training year where the fellow will be embedded in a lab of a mentor to learn the new discipline and its culture.
Mathematics and Physical Sciences
Targeted Grants in MPS
The program is intended to support high-risk theoretical mathematics, physics and computer science projects of exceptional promise and scientific importance on a case-by-case basis.
Travel Support for Mathematicians
The goal of the program is to stimulate collaboration in the mathematics field primarily through the funding of travel and related expenditures.
Simons Collaborations in Mathematics and the Physical Sciences
The aim of the Simons Collaborations in MPS program is to stimulate progress on fundamental scientific questions of major importance in mathematics, theoretical physics and theoretical computer science.
Simons Fellows in Mathematics
The Simons Fellows program in Mathematics provides funds to faculty for up to a semester-long research leave from classroom teaching and administrative obligations.
Targeted Grants to Institutes
The program is intended to support established institutes or centers in the mathematics and physical sciences through funding to help strengthen contacts within the international scientific community.
NSF-Simons Collaboration on a National Institute for Theory and Mathematics in Biology (NITMB)
The National Science Foundation Directorates for Mathematical and Physical Sciences (NSF/MPS) and for Biological Sciences (NSF/BIO) and the Simons Foundation Division of Mathematics and Physical Sciences (SF/MPS) shall jointly sponsor a new research institute to facilitate collaborations among groups of mathematicians (including statisticians and computational scientists) and biologists.
Each Simons Symposia series brings together mathematicians, theoretical physicists and/or theoretical computer scientists to interact and collaborate in a series of up to three symposia, held every second year and focusing on one topic or a tightly connected group of topics.
NSF-Simons Research Collaborations on the Mathematical and Scientific Foundations of Deep Learning
The NSF-Simons Research Collaborations on the MoDL initiative awarded two collaborations designed to support research activities focused on a particular set of topics involving some of the most challenging questions in the general area of mathematical and scientific foundations of deep learning.
Simons Postdoctoral Fellowships in Marine Microbial Ecology
The Simons Foundation invites applications for postdoctoral fellowships to support candidates who intend to pursue a career in basic research on fundamental problems in marine microbial ecology, with an emphasis on understanding the role of microorganisms in shaping ocean processes, and vice versa. The foundation is interested in applicants with training in different disciplines, including…
Simons Early Career Investigator in Aquatic Microbial Ecology and Evolution Awards
This program was titled “Early Career Investigator in Marine Microbial Ecology and Evolution Awards” from 2015-2022. The purpose of these awards is to help launch the careers of outstanding investigators in the fields of microbial ecology and evolution in marine or natural freshwater systems, who will advance our understanding through experiments, modeling or theory. Investigators…
Simons Investigator in Aquatic Microbial Ecology Awards
The purpose of these awards is to support recently tenured, outstanding investigators in the field of microbial ecology in marine or natural freshwater systems, who will advance our understanding through field studies, laboratory experiments, modeling or theory. The program will provide support for establishment of a new research direction or an innovative expansion of current…
Moore-Simons Project on the Origin of the Eukaryotic Cell
The Simons Foundation and the Gordon and Betty Moore Foundation are pleased to announce the Moore–Simons Project on the Origin of the Eukaryotic Cell. The Simons Foundation’s Life Sciences division and the Gordon and Betty Moore Foundation’s Symbiosis in Aquatic Systems Initiative are jointly soliciting proposals for research on the origin of the eukaryotic cell.
Simons Foundation Undergraduate Research Fellowship in Neuroscience (SURFiN)
The goal of the Simons Foundation Undergraduate Research Fellowship in Neuroscience (SURFiN) Program is to spark and sustain interest in neuroscience among undergraduate students from diverse backgrounds underrepresented in neuroscience research. SURFiN provides funds and programming for undergraduate research assistants (fellows) to work in-person in Simons Foundation-supported neuroscience laboratories under the mentorship of graduate students…
Neuroscience Collaborations Vision Statements Call
The Simons Foundation The Simons Foundation’s mission is to advance the frontiers of research in mathematics and the basic sciences.… Read More
SCPAB Transition to Independence Award
The Simons Collaboration on Plasticity and the Aging Brain (SCPAB) Transition to Independence Award aims to facilitate the transition of the next generation of outstanding scientists from historically underrepresented groups to research independence in the field of cognitive aging.
SCGB Transition to Independence Award
The Simons Collaboration on the Global Brain is dedicated to supporting advances in systems and computational neuroscience with the goal of expanding our understanding of the brain's internal states. The Transition to Independence (TTI) Award in Systems and Computational Neuroscience aims to facilitate the transition of outstanding systems and computational neuroscientists from historically underrepresented backgrounds…
SCGB Conference Awards
The Simons Collaboration on the Global Brain (SCGB) is accepting applications for funding of courses or conferences relevant to the SCGB mission. Courses and conferences that focus on the fields of systems and computational neuroscience are encouraged to apply. You can find more information on the SCGB program here.
2021 Pilot Awards
Mission The Simons Collaboration on the Global Brain (SCGB) aims to expand our understanding of the role of internal brain… Read More
SCGB Conference Awards (2019 Cycle)
The Simons Collaboration on the Global Brain (SCGB) is accepting applications for funding of courses, conferences, and workshops relevant to the SCGB mission.
Autism Research (SFARI)
2023 Human Cognitive and Behavioral Science – Request for Applications
The Human Cognitive and Behavioral Science RFA prioritizes research that produces foundational knowledge about the neurobehavioral differences associated with ASD. These projects are expected to inform or relate to the development and refinement of tools needed for translational efforts, such as biomarkers and outcome measures. Special emphasis is placed on objective, quantitative measures that may…
Simons Foundation Undergraduate Research Fellowship in Neuroscience (SURFiN)
The goal of the Simons Foundation Undergraduate Research Fellowship in Neuroscience (SURFiN) Program is to spark and sustain interest in neuroscience among undergraduate students from diverse backgrounds underrepresented in neuroscience research. Prior laboratory experience is not required. SURFiN fellows complete an in-person, paid undergraduate research assistantship in Simons Foundation-supported neuroscience laboratories during the 2023–2024 academic…
2023 Cross-Species Studies of ASD — Request for Applications
Grants awarded through the Cross-Species Studies of ASD request for applications (RFA) are intended to support multi-disciplinary teams of PIs with expertise in both human and animal research to perform coordinated cross-species studies to advance our understanding of ASD-relevant behaviors and their underlying neurobiological mechanisms, with the potential for developing novel biomarkers or interventions. Applicants…
Bridge to Independence Award Program
SFARI is invested in supporting the next generation of top autism researchers. The Bridge to Independence Award program engages talented early-career scientists to pursue autism research by facilitating their transition to research independence and providing grant funding at the start of their faculty positions at a U.S. or international research institution. Applications from groups that…
2023 Winter Pilot Award – Request for Applications
Grants awarded through this RFA are intended to provide early support for exploratory ideas, particularly those with novel hypotheses for autism. Appropriate projects for this mechanism include those considered higher risk with less assurance of ultimate impact, but with the potential for transformative results. Investigators new to the field of autism are encouraged to apply…
Genomics of ASD: Pathways to Biological Convergence and Genetic Therapies – Request for Applications
Grants awarded through this request for applications (RFA) are intended to improve our understanding of the molecular and cellular consequences of genetic risk for ASD, and to provide a foundation for the development of new therapies. Special emphasis is placed on the use of scalable methods, especially as applied to genes that are suitable targets…
SPARK Research Match Diversity, Equity and Inclusivity – Request for applications
The SPARK Research Match Diversity, Equity and Inclusivity RFA aims to address historic disparities in research participation by Black or African American individuals by soliciting studies on autism that recruit Black or African American participants. Funding will provide per-person participant incentive (e-gift cards) for participation in projects that utilize SPARK Research Match to recruit participants…
Analysis of postmortem brain tissue from the Autism BrainNet collection — Request for applications
Grants awarded through this request for applications are intended to advance the understanding of autism spectrum disorder through analyses of human postmortem brain tissue donated to the Autism BrainNet collection. The annual budget is between $300,000 and $1,000,000, inclusive of 20 percent indirect costs, for a period of two (2) years. We encourage…
Autism Rat Models Consortium – Request for Applications
Grants awarded through this RFA are intended to capitalize on the rat as a model system to advance our understanding of the behavioral and circuit neuroscience mechanisms driving autism. This RFA will support a consortium of investigators to collaboratively use SFARI autism rat models to examine the biological basis of complex behaviors and the underlying…
Maternal COVID-19 as a potential risk for autism: Supplemental funding for ongoing pregnancy cohorts – Request for applications
Grants awarded through this RFA will supplement funding from other agencies for ongoing pregnancy cohorts to broaden biospecimen collection and to extend post-natal family tracking. These cohorts and biospecimen collections can be leveraged in future research to understand the effects of gestational infection and inflammation on autism risk in children. The maximum budget is $250,000…
2020 SFARI Collaboration on Sex Differences in Autism — Request for Applications
SFARI Collaborations are a new funding mechanism that will provide substantive and stable funding support to multidisciplinary teams of investigators tackling critical issues in the autism research field. Collaborations will be led by a director who oversees interdisciplinary, synergistic research efforts across multiple laboratories. Investigative groups within a Collaboration will focus on the same conceptually…
2020 Research Award – Request for Applications
Grants awarded through this RFA are intended to provide support for the investigation of key unresolved research questions in autism, particularly those that connect etiology to brain function and behavior. SFARI welcomes risk and novelty in Research Award proposals, but potential impact on the autism research field will be the most important criterion. Competitive applications…
2019 Novel Outcome Measures in ASD Request for Applications
Grants awarded through this request for applications are intended to develop and validate outcome measures that are suitable for use in intervention studies that target the core symptoms of autism spectrum disorder. Such measures should provide objective data with strong psychometric properties, be scalable for use in large, multisite studies, not be unduly burdensome to…
2019 SPARK Clinical Site Network Request for Applications
SPARK is a SFARI initiative intended to recruit, engage and retain a community of 50,000 individuals with autism, and their family members, in the United States. This research cohort includes children and adults who span the full autism spectrum and individuals of all socio-demographic backgrounds. Through this RFA, SFARI will add additional clinical sites to…
Genomic Analysis for Autism Risk Variants in SPARK – Request for Applications
Grants awarded through this RFA are intended to advance our understanding of the genetic basis of autism. Investigators who are interested in analyzing genomic data in innovative ways from thousands of SPARK families are encouraged to apply. Available data will include whole-exome and genome-wide genotyping data from approximately 4,500 individuals with autism spectrum disorder (ASD)…
Explorer Awards RFA
Application type for proposals requesting support of exploratory experiments that will strengthen hypotheses and lead to the formulation of competitive applications for subsequent larger-scale funding by SFARI or other organizations. Innovative, high-risk/high-impact proposals are encouraged. We especially encourage applications from investigators who are new to the field of autism, but who have expertise that could…
Whole-Genome Analysis for Autism Risk Variants Request for Applications
Grants awarded through this RFA are intended to advance our understanding of the genetic basis of autism, and in particular, to begin to assess genetic variants conferring risk in non-coding regions and in coding regions of the genome that may be less accessible to whole-exome sequencing. Investigators who are interested in developing innovative and efficient…
Functional Screen of Autism-Associated Variants Request for Applications
Grants awarded through this RFA are intended to advance our understanding of the genetic basis of autism, and in particular the potential role of missense and in-frame deletion variants in conferring risk. Investigators who are interested in developing medium- or high-throughput screens to test the functional effects of missense and in-frame deletion variants identified in…
Innate Immune System Impact Request for Applications
Grants awarded through this RFA are intended to advance our understanding of the impact of activation of the innate immune system on behavioral, circuit, synaptic and neuronal functions in order to understand the consequences of infection and immune activation on autism-related behaviors. Experiments should include physiologically relevant activation/inhibition of the innate immune system in animal…
Circuit Dynamics Request for Applications
Grants awarded through this RFA are intended to advance our understanding of the circuit basis for behavioral and cognitive alterations relevant to autism spectrum disorders. The goal is to determine the downstream consequences of autism-associated genetic perturbations on neural circuitry, with an emphasis on how collections of neurons operate in concert during autism-relevant behaviors. Experiments…
Analysis of Simons VIP Biospecimens Request for Applications
This RFA seeks proposals that take advantage of the unique combination of biospecimens and rich phenotypic information collected by the Simons Variation in Individuals Project (Simons VIP). Although SFARI is open to many different approaches, we will likely give priority to those that aim to accomplish a comprehensive characterization of RNA expression differences and correlate…
Mouse phenotyping request for applications
This RFA seeks proposals that aim to comprehensively analyze the behavior of mouse models that have been generated with targeted genetic mutations based on strong human genetic evidence implicating them in autism spectrum disorders. We expect investigators will test at least three genetic models in the same background strain (C57BL/6). In addition, investigators should analyze…
SFARI Supplement to Enhance Equity and Diversity (SEED) — Request for Applications
The SFARI Supplement to Enhance Equity and Diversity (SEED) is a new program that provides supplements to existing grants for the recruitment of new lab members from American underrepresented minority groups at the postdoctoral level. For the purposes of this supplement, eligible groups include the following: African American/Black; Latin American/Hispanic; Native American/Alaskan Native; Native Hawaiian/other…